Cellular immunity to the G1 domain of cartilage proteoglycan aggrecan is enhanced in patients with rheumatoid arthritis but only after removal of keratan sulfate.
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Proteoglycan aggrecan conducting T cell activation and apoptosis in a murine model of rheumatoid arthritisDeglycosylation of glycoproteins with trifluoromethanesulphonic acid: elucidation of molecular structure and function.Induction of arthritis in HLA-DR4-humanized and HLA-DQ8-humanized mice by human cartilage proteoglycan aggrecan but only in the presence of an appropriate (non-MHC) genetic background.Transgenic mouse models of rheumatoid arthritis.Impaired activation-induced cell death promotes spontaneous arthritis in antigen (cartilage proteoglycan)-specific T cell receptor-transgenic miceA longitudinal study on an autoimmune murine model of ankylosing spondylitis.Novel self-epitopes derived from aggrecan, fibrillin, and matrix metalloproteinase-3 drive distinct autoreactive T-cell responses in juvenile idiopathic arthritis and in health.Arthritogenic T cells drive the recovery of autoantibody-producing B cell homeostasis and the adoptive transfer of arthritis in SCID miceNon-MHC risk alleles in rheumatoid arthritis and in the syntenic chromosome regions of corresponding animal models.An epitope-specific DerG-PG70 LEAPS vaccine modulates T cell responses and suppresses arthritis progression in two related murine models of rheumatoid arthritisInduction of arthritis in SCID mice by T cells specific for the "shared epitope" sequence in the G3 domain of human cartilage proteoglycan.Specific presence of intracellular citrullinated proteins in rheumatoid arthritis synovium: relevance to antifilaggrin autoantibodies.Experimental immunity to the G1 domain of the proteoglycan versican induces spondylitis and sacroiliitis, of a kind seen in human spondylarthropathies.Keratan Sulphate, a complex Glycosaminoglycan with Unique Functional Capability.Induction of proliferation and pro-inflammatory cytokine production in rheumatoid arthritis peripheral blood mononuclear cells by a 65 KDa chondrocyte membrane-specific, constitutive target autoantigen (CH65).Unconventional T-cell recognition of an arthritogenic epitope of proteoglycan aggrecan released from degrading cartilage.
P2860
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P2860
Cellular immunity to the G1 domain of cartilage proteoglycan aggrecan is enhanced in patients with rheumatoid arthritis but only after removal of keratan sulfate.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
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1998年學術文章
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name
Cellular immunity to the G1 do ...... er removal of keratan sulfate.
@en
Cellular immunity to the G1 do ...... er removal of keratan sulfate.
@nl
type
label
Cellular immunity to the G1 do ...... er removal of keratan sulfate.
@en
Cellular immunity to the G1 do ...... er removal of keratan sulfate.
@nl
prefLabel
Cellular immunity to the G1 do ...... er removal of keratan sulfate.
@en
Cellular immunity to the G1 do ...... er removal of keratan sulfate.
@nl
P2093
P2860
P1476
Cellular immunity to the G1 do ...... er removal of keratan sulfate.
@en
P2093
Banerjee S
Fitzcharles MA
Guerassimov A
Rosenberg LC
P2860
P304
P356
10.1002/1529-0131(199806)41:6<1019::AID-ART8>3.0.CO;2-X
P577
1998-06-01T00:00:00Z