Jumping the Barrier: Modeling Drug Penetration across the Blood-Brain Barrier.

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Jumping the Barrier: Modeling Drug Penetration across the Blood-Brain Barrier.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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Jumping the Barrier: Modeling Drug Penetration across the Blood-Brain Barrier.

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Jumping the Barrier: Modeling Drug Penetration across the Blood-Brain Barrier.

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Item

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Jumping the Barrier: Modeling Drug Penetration across the Blood-Brain Barrier.

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Jumping the Barrier: Modeling Drug Penetration across the Blood-Brain Barrier.

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Jumping the Barrier: Modeling Drug Penetration across the Blood-Brain Barrier.

@en

Jumping the Barrier: Modeling Drug Penetration across the Blood-Brain Barrier.

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P1476

Jumping the Barrier: Modeling Drug Penetration across the Blood-Brain Barrier.

@en

P2093

Cindy H Chau

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Cody J Peer

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William D Figg

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P2860

Development of a permeability-limited model of the human brain and cerebrospinal fluid (CSF) to integrate known physiological and biological knowledge: Estimating time varying CSF drug concentrations and their variability using in vitro data.

The Efficacy of the Wee1 Inhibitor MK-1775 Combined with Temozolomide Is Limited by Heterogeneous Distribution across the Blood-Brain Barrier in Glioblastoma

Physiologically based pharmacokinetic modelling of drug penetration across the blood-brain barrier--towards a mechanistic IVIVE-based approach

Acid pH in tumors and its potential for therapeutic exploitation.

Quantitative and Mechanistic Understanding of AZD1775 Penetration across Human Blood-Brain Barrier in Glioblastoma Patients Using an IVIVE-PBPK Modeling Approach.

Cellular pH gradient in tumor versus normal tissue: potential exploitation for the treatment of cancer.

P304

7437-7439

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scholarly article

P356

10.1158/1078-0432.CCR-17-2741

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P407

English

P433

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P478

http://www.w3.org/2001/XMLSchema#string

P577

2017-10-10T00:00:00Z

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P698

29018050

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P921

blood–brain barrier

P932

5732885

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