Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway.
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Knockdown of glutamate-cysteine ligase by small hairpin RNA reveals that both catalytic and modulatory subunits are essential for the survival of primary neurons6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysisAMPK in the brain: its roles in energy balance and neuroprotectionRegulation of glucose metabolism by p53: emerging new roles for the tumor suppressorMitochondrial defects in acute multiple sclerosis lesionsAMPK as a potential anticancer target - friend or foe?Cell Biology Symposium: feed efficiency: mitochondrial function to global gene expressionLeptin, a mediator of cardiac damage associated with obesityThe emerging role of AMPK in the regulation of breathing and oxygen supplyEfavirenz and the CNS: what we already know and questions that need to be answeredReduced methylation of PFKFB3 in cancer cells shunts glucose towards the pentose phosphate pathway6-Phosphofructo-2-kinase (pfkfb3) gene promoter contains hypoxia-inducible factor-1 binding sites necessary for transactivation in response to hypoxiaA multi-targeted approach to suppress tumor-promoting inflammationUnbiased gene expression analysis implicates the huntingtin polyglutamine tract in extra-mitochondrial energy metabolismInhibition of mitochondrial respiration by nitric oxide rapidly stimulates cytoprotective GLUT3-mediated glucose uptake through 5'-AMP-activated protein kinaseNitrite activates AMP kinase to stimulate mitochondrial biogenesis independent of soluble guanylate cyclaseCdk5 phosphorylates Cdh1 and modulates cyclin B1 stability in excitotoxicityLoss of VPS13C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent MitophagyThe LKB1-AMPK pathway: metabolism and growth control in tumour suppressionMitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and ParkinBrain lactate metabolism: the discoveries and the controversies.Astrocyte NMDA receptors' activity sustains neuronal survival through a Cdk5-Nrf2 pathway.The micro-architecture of the cerebral cortex: functional neuroimaging models and metabolism.E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferationAltered Metabolic Profiles Associate with Toxicity in SOD1G93A Astrocyte-Neuron Co-Cultures.How Energy Metabolism Supports Cerebral Function: Insights from 13C Magnetic Resonance Studies In vivoNanomolar nitric oxide concentrations quickly and reversibly modulate astrocytic energy metabolismiNOS-derived nitric oxide promotes glycolysis by inducing pyruvate kinase M2 nuclear translocation in ovarian cancerGlycolysis-dependent histone deacetylase 4 degradation regulates inflammatory cytokine production.Hypothalamic nitric oxide in hypoglycemia detection and counterregulation: a two-edged sword.Adventures in vascular biology: a tale of two mediators.Senescence-associated phenotypes in Akita diabetic mice are enhanced by absence of bradykinin B2 receptors.Cyclin D1 Restrains Oncogene-Induced Autophagy by Regulating the AMPK-LKB1 Signaling Axis.Impact of nutrient excess and endothelial nitric oxide synthase on the plasma metabolite profile in mice.Mitochondria as signaling organelles in the vascular endotheliumMethylglyoxal, the dark side of glycolysis5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments.NAD+ depletion or PAR polymer formation: which plays the role of executioner in ischaemic cell death?Chronic NOS inhibition accelerates NAFLD progression in an obese rat model.DJ1 represses glycolysis and cell proliferation by transcriptionally up-regulating Pink1.
P2860
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P2860
Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Nitric oxide switches on glyco ...... hosphofructo-2-kinase pathway.
@en
Nitric oxide switches on glyco ...... hosphofructo-2-kinase pathway.
@nl
type
label
Nitric oxide switches on glyco ...... hosphofructo-2-kinase pathway.
@en
Nitric oxide switches on glyco ...... hosphofructo-2-kinase pathway.
@nl
prefLabel
Nitric oxide switches on glyco ...... hosphofructo-2-kinase pathway.
@en
Nitric oxide switches on glyco ...... hosphofructo-2-kinase pathway.
@nl
P2860
P356
P1433
P1476
Nitric oxide switches on glyco ...... phosphofructo-2-kinase pathway
@en
P2093
Salvador Moncada
P2860
P2888
P356
10.1038/NCB1080
P577
2003-12-14T00:00:00Z