Elevation of intracellular glucosylceramide levels results in an increase in endoplasmic reticulum density and in functional calcium stores in cultured neurons. - Wikidata - wikimedia - TriplyDB

Elevation of intracellular glucosylceramide levels results in an increase in endoplasmic reticulum density and in functional calcium stores in cultured neurons.

Elevation of intracellular glucosylceramide levels results in an increase in endoplasmic reticulum density and in functional calcium stores in cultured neurons.

http://www.wikidata.org/entity/Q48153561

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Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1 Klotho-related protein is a novel cytosolic neutral beta-glycosylceramidase Chemical and biological approaches for adapting proteostasis to ameliorate protein misfolding and aggregation diseases: progress and prognosis The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiology Lysosome and calcium dysregulation in Alzheimer's disease: partners in crime Inhibition of calcium uptake via the sarco/endoplasmic reticulum Ca2+-ATPase in a mouse model of Sandhoff disease and prevention by treatment with N-butyldeoxynojirimycin Aberrant Ca2+ handling in lysosomal storage disorders Common and uncommon pathogenic cascades in lysosomal storage diseases Gaucher disease ascertained through a Parkinson's center: imaging and clinical characterization.Age-dependent therapeutic effect of memantine in a mouse model of juvenile Batten disease Type 2 Gaucher disease: phenotypic variation and genotypic heterogeneity.Gaucher disease: pathological mechanisms and modern management.Regulating survival and development in the retina: key roles for simple sphingolipids.Remodeling the proteostasis network to rescue glucocerebrosidase variants by inhibiting ER-associated degradation and enhancing ER folding.Endoplasmic reticulum Ca(2+) handling in excitable cells in health and disease Unbiased Cell-based Screening in a Neuronal Cell Model of Batten Disease Highlights an Interaction between Ca2+ Homeostasis, Autophagy, and CLN3 Protein Function.Role of endolysosomes in HIV-1 Tat-induced neurotoxicity Gaucher disease gene GBA functions in immune regulation.Progression of Behavioral and CNS Deficits in a Viable Murine Model of Chronic Neuronopathic Gaucher Disease.Storage solutions: treating lysosomal disorders of the brain.Neuroinflammatory paradigms in lysosomal storage diseases.Neuronopathic Gaucher disease: dysregulated mRNAs and miRNAs in brain pathogenesis and effects of pharmacologic chaperone treatment in a mouse model Targeted Plasma Membrane Delivery of a Hydrophobic Cargo Encapsulated in a Liquid Crystal Nanoparticle Carrier.The cognitive profile of type 1 Gaucher disease patients.Acidic Ca2+ stores in neurodegeneration.A new glucocerebrosidase-deficient neuronal cell model provides a tool to probe pathophysiology and therapeutics for Gaucher disease.β-Glucosidase 2 (GBA2) activity and imino sugar pharmacology.Covalent inhibitors of glycosidases and their applications in biochemistry and biology.Upregulation of proinflammatory cytokines in the fetal brain of the Gaucher mouse.Accumulation of ordered ceramide-cholesterol domains in farber disease fibroblasts.Strategies for delivery of therapeutics into the central nervous system for treatment of lysosomal storage disorders.Endoplasmic-reticulum calcium depletion and disease.Lysosomal storage disorders and Parkinson's disease: Gaucher disease and beyond.The cellular pathology of lysosomal diseases.Gaucher disease paradigm: from ERAD to comorbidity.Lysosomal storage diseases--the horizon expands.Endoplasmic reticulum and lysosomal Ca²⁺ stores are remodelled in GBA1-linked Parkinson disease patient fibroblasts.Chronic pain in Gaucher disease: skeletal or neuropathic origin?Current and Novel Aspects on the Non-lysosomal β-Glucosylceramidase GBA2.Pharmaceutical Chaperones and Proteostasis Regulators in the Therapy of Lysosomal Storage Disorders: Current Perspective and Future Promises.

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P2860

Elevation of intracellular glucosylceramide levels results in an increase in endoplasmic reticulum density and in functional calcium stores in cultured neurons.

http://www.wikidata.org/entity/Q48153561

description

1999 nî lūn-bûn

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1999年の論文

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1999年学术文章

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1999年学术文章

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1999年学术文章

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1999年学术文章

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1999年学术文章

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1999年學術文章

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1999年學術文章

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name

Elevation of intracellular glu ...... um stores in cultured neurons.

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Elevation of intracellular glu ...... um stores in cultured neurons.

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type

label

Elevation of intracellular glu ...... um stores in cultured neurons.

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Elevation of intracellular glu ...... um stores in cultured neurons.

@nl

prefLabel

Elevation of intracellular glu ...... um stores in cultured neurons.

@en

Elevation of intracellular glu ...... um stores in cultured neurons.

@nl

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Elevation of intracellular glu ...... um stores in cultured neurons.

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P2860

Differential effects of glycolipid biosynthesis inhibitors on ceramide-induced cell death in neuroblastoma cells

Prevention of lysosomal storage in Tay-Sachs mice treated with N-butyldeoxynojirimycin

A novel fluorescent ceramide analogue for studying membrane traffic in animal cells: accumulation at the Golgi apparatus results in altered spectral properties of the sphingolipid precursor

Demonstration of direct glycosylation of nondegradable glucosylceramide analogs in cultured cells.

Multiple effects of opiates on intracellular calcium level and on calcium uptake in three neuronal cell lines.

Internalization and sorting of a fluorescent analogue of glucosylceramide to the Golgi apparatus of human skin fibroblasts: utilization of endocytic and nonendocytic transport mechanisms.

Decreased formation of inositol trisphosphate in Madin-Darby canine kidney cells under conditions of beta-glucosidase inhibition.

Intracellular calcium release mediated by sphingosine derivatives generated in cells.

Type 2 and type 3 Gaucher disease: a morphological and biochemical study.

Accumulation of glucosylceramide and glucosylsphingosine (psychosine) in cerebrum and cerebellum in infantile and juvenile Gaucher disease.

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endoplasmic reticulum