Joint immobilization prevents murine osteoarthritis and reveals the highly mechanosensitive nature of protease expression in vivo.
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Cellular ageing mechanisms in osteoarthritisGenetically Engineered Mouse Models Reveal the Importance of Proteases as Osteoarthritis Drug TargetsOsteoarthritis joint pain: the cytokine connectionOsteoblast-chondrocyte interactions in osteoarthritisNight-time immobilization of the distal interphalangeal joint reduces pain and extension deformity in hand osteoarthritis.The mechanobiology of articular cartilage: bearing the burden of osteoarthritis.Transcriptional analysis of micro-dissected articular cartilage in post-traumatic murine osteoarthritis.Type VI Collagen Regulates Pericellular Matrix Properties, Chondrocyte Swelling, and Mechanotransduction in Mouse Articular CartilageTemporal gene expression profiling of the rat knee joint capsule during immobilization-induced joint contractures.Do mouse models reflect the diversity of osteoarthritis in humans?Exercise-driven metabolic pathways in healthy cartilage.Nociceptive Sensitizers Are Regulated in Damaged Joint Tissues, Including Articular Cartilage, When Osteoarthritic Mice Display Pain Behavior.Acute Molecular Changes in Synovial Fluid Following Human Knee Injury: Association With Early Clinical Outcomes.TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading.Loss of extracellular matrix from articular cartilage is mediated by the synovium and ligament after anterior cruciate ligament injury.A gene expression study of normal and damaged cartilage in anteromedial gonarthrosis, a phenotype of osteoarthritis.CCL2 and CCR2 regulate pain-related behaviour and early gene expression in post-traumatic murine osteoarthritis but contribute little to chondropathy.Mouse models of osteoarthritis: modelling risk factors and assessing outcomes.Cartilage regeneration for treatment of osteoarthritis: a paradigm for nonsurgical intervention.Mechanical instability and titanium particles induce similar transcriptomic changes in a rat model for periprosthetic osteolysis and aseptic loosening.Fibroblast growth factor 2 drives changes in gene expression following injury to murine cartilage in vitro and in vivoUsing mouse models to investigate the pathophysiology, treatment, and prevention of post-traumatic osteoarthritis.Protection against murine osteoarthritis by inhibition of the 26S proteasome and lysine-48 linked ubiquitination.Models to define the stages of articular cartilage degradation in osteoarthritis development.Induced superficial chondrocyte death reduces catabolic cartilage damage in murine posttraumatic osteoarthritis.Synchrotron- and laboratory-based X-ray phase-contrast imaging for imaging mouse articular cartilage in the absence of radiopaque contrast agents.Matriptase Induction of Metalloproteinase-Dependent Aggrecanolysis In Vitro and In Vivo: Promotion of Osteoarthritic Cartilage Damage by Multiple MechanismsArticular chondrocyte alignment in the rat after surgically induced osteoarthritis.Insulin-Like Growth Factor II (IGF-II) Inhibits IL-1β-Induced Cartilage Matrix Loss and Promotes Cartilage Integrity in Experimental Osteoarthritis.ADAMTS-4 activity in synovial fluid as a biomarker of inflammation and effusion.Supramolecular synergy in the boundary lubrication of synovial joints.Transcriptomics of wild-type mice and mice lacking ADAMTS-5 activity identifies genes involved in osteoarthritis initiation and cartilage destruction.CCL2/CCR2, but not CCL5/CCR5, mediates monocyte recruitment, inflammation and cartilage destruction in osteoarthritis.Peroxisome proliferator-activated receptor δ promotes the progression of posttraumatic osteoarthritis in a mouse model.TSG-6 - a double-edged sword for osteoarthritis (OA).Healing of Osteochondral Defects via Endochondral Ossification in an Ovine Model.Reduction in disease progression by inhibition of transforming growth factor α-CCL2 signaling in experimental posttraumatic osteoarthritis.Early Changes of Articular Cartilage and Subchondral Bone in The DMM Mouse Model of Osteoarthritis.Early, focal changes in cartilage cellularity and structure following surgically induced meniscal destabilization in the mouse.Evidence of cartilage repair by joint distraction in a canine model of osteoarthritis.
P2860
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P2860
Joint immobilization prevents murine osteoarthritis and reveals the highly mechanosensitive nature of protease expression in vivo.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Joint immobilization prevents ...... f protease expression in vivo.
@en
Joint immobilization prevents ...... f protease expression in vivo.
@nl
type
label
Joint immobilization prevents ...... f protease expression in vivo.
@en
Joint immobilization prevents ...... f protease expression in vivo.
@nl
prefLabel
Joint immobilization prevents ...... f protease expression in vivo.
@en
Joint immobilization prevents ...... f protease expression in vivo.
@nl
P2093
P2860
P356
P1476
Joint immobilization prevents ...... f protease expression in vivo.
@en
P2093
Annika Burleigh
Clare Driscoll
Jeremy Saklatvala
Matthew D Gardiner
Olga Boruc
P2860
P304
P356
10.1002/ART.34420
P577
2012-07-01T00:00:00Z