Glycine modulates [3H]MK-801 binding to the NMDA receptor in rat brain.
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Enantiomers of HA-966 (3-amino-1-hydroxypyrrolid-2-one) exhibit distinct central nervous system effects: (+)-HA-966 is a selective glycine/N-methyl-D-aspartate receptor antagonist, but (-)-HA-966 is a potent gamma-butyrolactone-like sedative7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complexModulation of seizure susceptibility in the mouse by the strychnine-insensitive glycine recognition site of the NMDA receptor/ion channel complex.Cycloleucine blocks NMDA responses in cultured hippocampal neurones under voltage clamp: antagonism at the strychnine-insensitive glycine receptorPostnatal changes in N-methyl-D-aspartate receptor binding and stimulation by glutamate and glycine of [3H]-MK-801 binding in human temporal cortexChallenges and opportunities for drug discovery in psychiatric disorders: the drug hunters' perspective.MK-801 is a potent nematocidal agent. Characterization of MK-801 binding sites in Caenorhabditis elegans.The mechanism of action and pharmacological specificity of the anticonvulsant NMDA antagonist MK-801: a voltage clamp study on neuronal cells in cultureAlteration of [3H]MK-801 binding associated with the N-methyl-D-Aspartate receptor complex by acute ethanol in rat cortex and hippocampus in vitro.1-Aminocyclopropane carboxylic acid: a potent and selective ligand for the glycine modulatory site of the N-methyl-D-aspartate receptor complex.Inhibition by calmodulin antagonists of [3H]MK-801 binding in brain synaptic membranes.Glycine binding to rat cortex and spinal cord: binding characteristics and pharmacology reveal distinct populations of sites.Characterization of a [3H]glycine recognition site as a modulatory site of the N-methyl-D-aspartate receptor complex.[3H]thienylcyclohexylpiperidine binding activity in brain synaptic membranes treated with Triton X-100.beta-Amyloid (25-35) or substance P stimulates [3H]MK-801 binding to rat cortical membranes in the presence of glutamate and glycine.Regionally distinct N-methyl-D-aspartate receptors distinguished by quantitative autoradiography of [3H]MK-801 binding in rat brain.Endogenous D-serine in rat brain: N-methyl-D-aspartate receptor-related distribution and aging.Support for radiolabeling of a glycine recognition domain on the N-methyl-D-aspartate receptor ionophore complex by 5,7-[3H]dichlorokynurenate in rat brain.Differential modulation by divalent cations of [3H]MK-801 binding in brain synaptic membranes.Examination of parameters influencing [3H]MK-801 binding in postmortem human cortex.Characterisation of the glycine modulatory site of the N-methyl-D-aspartate receptor-ionophore complex in human brain.Glutamate receptors in the frontal cortex of alcoholics.Characterisation of [3H]MK-801 binding and its cooperative modulation by pig brain membranes.Interaction of strychnine-insensitive glycine binding with MK-801 binding in brain synaptic membranes.Polyamine binding sites in the rat brain hippocampus plasma membranes: MK 801 does not influence the binding process.Reduced glycine stimulation of [3H]MK-801 binding in Alzheimer's disease.
P2860
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P2860
Glycine modulates [3H]MK-801 binding to the NMDA receptor in rat brain.
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年学术文章
@wuu
1987年学术文章
@zh-cn
1987年学术文章
@zh-hans
1987年学术文章
@zh-my
1987年学术文章
@zh-sg
1987年學術文章
@yue
1987年學術文章
@zh
1987年學術文章
@zh-hant
name
Glycine modulates [3H]MK-801 binding to the NMDA receptor in rat brain.
@en
Glycine modulates [3H]MK-801 binding to the NMDA receptor in rat brain.
@nl
type
label
Glycine modulates [3H]MK-801 binding to the NMDA receptor in rat brain.
@en
Glycine modulates [3H]MK-801 binding to the NMDA receptor in rat brain.
@nl
prefLabel
Glycine modulates [3H]MK-801 binding to the NMDA receptor in rat brain.
@en
Glycine modulates [3H]MK-801 binding to the NMDA receptor in rat brain.
@nl
P2093
P1476
Glycine modulates [3H]MK-801 binding to the NMDA receptor in rat brain.
@en
P2093
P304
P356
10.1016/0014-2999(87)90095-1
P407
P577
1987-10-01T00:00:00Z