Truncation of the MSH2 C-terminal 60 amino acids disrupts effective DNA mismatch repair and is causative for Lynch syndrome.

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Truncation of the MSH2 C-terminal 60 amino acids disrupts effective DNA mismatch repair and is causative for Lynch syndrome.

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2016 nî lūn-bûn

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2016年の論文

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年學術文章

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2016年學術文章

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2016年學術文章

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Truncation of the MSH2 C-termi ...... causative for Lynch syndrome.

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Truncation of the MSH2 C-termi ...... causative for Lynch syndrome.

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Truncation of the MSH2 C-termi ...... causative for Lynch syndrome.

@en

Truncation of the MSH2 C-termi ...... causative for Lynch syndrome.

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Truncation of the MSH2 C-termi ...... causative for Lynch syndrome.

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Truncation of the MSH2 C-termi ...... causative for Lynch syndrome.

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P1476

Truncation of the MSH2 C-termi ...... s causative for Lynch syndrome

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P2093

Elly Delzenne-Goette

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Eva Wielders

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Martin van der Valk

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Rob Dekker

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P2860

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

Mechanism of mismatch recognition revealed by human MutSβ bound to unpaired DNA loops

The crystal structure of DNA mismatch repair protein MutS binding to a G x T mismatch

Escherichia coli MutS tetramerization domain structure reveals that stable dimers but not tetramers are essential for DNA mismatch repair in vivo

Structure of the human MutSalpha DNA lesion recognition complex

hMSH2-hMSH6 forms a hydrolysis-independent sliding clamp on mismatched DNA

Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer

HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions

Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase.

Molecular analysis of hereditary nonpolyposis colorectal cancer in the United States: high mutation detection rate among clinically selected families and characterization of an American founder genomic deletion of the MSH2 gene.

P2888

s10689-016-9945-x

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221-229

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scholarly article

P356

10.1007/S10689-016-9945-X

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P433

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P478

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P50

Hein Te Riele

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2017-04-01T00:00:00Z

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P698

27873144

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