Merlin links to the cAMP neuronal signaling pathway by anchoring the RIbeta subunit of protein kinase A. - Wikidata - wikimedia - TriplyDB

Merlin links to the cAMP neuronal signaling pathway by anchoring the RIbeta subunit of protein kinase A.

Merlin links to the cAMP neuronal signaling pathway by anchoring the RIbeta subunit of protein kinase A.

http://www.wikidata.org/entity/Q48236413

about

Magicin, a novel cytoskeletal protein associates with the NF2 tumor suppressor merlin and Grb2 Splicing factor arginine/serine-rich 17A (SFRS17A) is an A-kinase anchoring protein that targets protein kinase A to splicing factor compartments A neuronal function of the tumor suppressor protein merlin Structure of D-AKAP2:PKA RI Complex: Insights into AKAP Specificity and Selectivity Localization and quaternary structure of the PKA RI holoenzyme Cyclic AMP-dependent protein kinase phosphorylates merlin at serine 518 independently of p21-activated kinase and promotes merlin-ezrin heterodimerization Merlin, a "magic" linker between extracellular cues and intracellular signaling pathways that regulate cell motility, proliferation, and survival A functional association between merlin and HEI10, a cell cycle regulator.Neuronal microtubule-associated protein 2D is a dual a-kinase anchoring protein expressed in rat ovarian granulosa cells.Anchoring of protein kinase A by ERM (ezrin-radixin-moesin) proteins is required for proper netrin signaling through DCC (deleted in colorectal cancer)Self-masking in an intact ERM-merlin protein: an active role for the central alpha-helical domain.Merlin and the ERM proteins in Schwann cells, neurons and growth cones.cAMP/PKA signalling reinforces the LATS-YAP pathway to fully suppress YAP in response to actin cytoskeletal changes.Tissue-specific ablation of Prkar1a causes schwannomas by suppressing neurofibromatosis protein production.Isoform-specific subcellular localization and function of protein kinase A identified by mosaic imaging of mouse brain.Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics.Scaffolding during the cell cycle by A-kinase anchoring proteins.Delineation of type I protein kinase A-selective signaling events using an RI anchoring disruptor.Dual specificity A-kinase anchoring proteins (AKAPs) contain an additional binding region that enhances targeting of protein kinase A type I.Protein kinase A-mediated phosphorylation of the NF2 tumor suppressor protein merlin at serine 10 affects the actin cytoskeleton.

P2860

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P2860

Merlin links to the cAMP neuronal signaling pathway by anchoring the RIbeta subunit of protein kinase A.

http://www.wikidata.org/entity/Q48236413

description

2003 nî lūn-bûn

@nan

2003年の論文

@ja

2003年学术文章

@wuu

2003年学术文章

@zh

2003年学术文章

@zh-cn

2003年学术文章

@zh-hans

2003年学术文章

@zh-my

2003年学术文章

@zh-sg

2003年學術文章

@yue

2003年學術文章

@zh-hant

name

Merlin links to the cAMP neuro ...... a subunit of protein kinase A.

@en

Merlin links to the cAMP neuro ...... a subunit of protein kinase A.

@nl

type

label

Merlin links to the cAMP neuro ...... a subunit of protein kinase A.

@en

Merlin links to the cAMP neuro ...... a subunit of protein kinase A.

@nl

prefLabel

Merlin links to the cAMP neuro ...... a subunit of protein kinase A.

@en

Merlin links to the cAMP neuro ...... a subunit of protein kinase A.

@nl

P1433

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P1433

Journal of Biological Chemistry

P1476

Merlin links to the cAMP neuro ...... a subunit of protein kinase A.

@en

P2093

Cathrine R Carlson

http://www.w3.org/2001/XMLSchema#string

Juha Kuja-Panula

http://www.w3.org/2001/XMLSchema#string

Kaija Alfthan

http://www.w3.org/2001/XMLSchema#string

Lutz Vossebein

http://www.w3.org/2001/XMLSchema#string

Olli Carpén

http://www.w3.org/2001/XMLSchema#string

Tambet Teesalu

http://www.w3.org/2001/XMLSchema#string

P2860

Molecular cloning, cDNA structure and tissue-specific expression of the human regulatory subunit RI beta of cAMP-dependent protein kinases

Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2

Ezrin is a cyclic AMP-dependent protein kinase anchoring protein

A novel mechanism of PKA anchoring revealed by solution structures of anchoring complexes

Hippocampal long-term depression and depotentiation are defective in mice carrying a targeted disruption of the gene encoding the RI beta subunit of cAMP-dependent protein kinase

Heterotypic and homotypic associations between ezrin and moesin, two putative membrane-cytoskeletal linking proteins

Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site

The molecular basis for protein kinase A anchoring revealed by solution NMR

Protein kinase A associates with cystic fibrosis transmembrane conductance regulator via an interaction with ezrin

Expression of the neurofibromatosis type 2 gene in human tissues

P304

41167-41172

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scholarly article

P356

10.1074/JBC.M306149200

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P433

42

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P478

278

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P50

Friedrich W. Herberg

Mikaela Grönholm

P577

2003-08-01T00:00:00Z

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P698

12896975

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