P-glycoprotein gene (MDR1) cDNA from human adrenal: normal P-glycoprotein carries Gly185 with an altered pattern of multidrug resistance.
about
The remarkable transport mechanism of P-glycoprotein: a multidrug transporter.Optimized approaches for quantification of drug transporters in tissues and cells by MRM proteomicsPharmacogenomics of Drug Metabolizing Enzymes and Transporters: Relevance to Precision MedicineATP-binding cassette B1 gene polymorphisms, mRNA expression and chemosensitivity to paclitaxel in non-small cell lung cancer cells.The yeast a-factor transporter Ste6p, a member of the ABC superfamily, couples ATP hydrolysis to pheromone export.Cross-talk between signalling pathways and the multidrug resistant protein MDR-1A synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function.A novel ATP-binding cassette transporter involved in multidrug resistance in the phytopathogenic fungus Penicillium digitatumPharmacogenomics of MDR1/ABCB1 gene: the influence on risk and clinical outcome of haematological malignancies.Multidrug resistance 1 gene in inflammatory bowel disease: a meta-analysis.ABC multidrug transporters: structure, function and role in chemoresistance.Pharmacogenetics of antidepressantsPharmacogenetics of MDR1 and its impact on the pharmacokinetics and pharmacodynamics of drugs.A striking quality control subcompartment in Saccharomyces cerevisiae: the endoplasmic reticulum-associated compartment.Establishment of a P-glycoprotein substrate screening model and its preliminary applicationSingle nucleotide polymorphisms in human P-glycoprotein: its impact on drug delivery and disposition.Overexpression of the multidrug resistance gene mdr3 in spontaneous and chemically induced mouse hepatocellular carcinomas.Pharmacology, pharmacokinetics and pharmacogenomics of paclitaxel.Molecular analysis of the multidrug transporter, P-glycoprotein.Functional characterization of a glycine 185-to-valine substitution in human P-glycoprotein by using a vaccinia-based transient expression system.Genetic polymorphisms in placental transporters: implications for fetal drug exposure to oral antidiabetic agents.ABC proteins protect the human body and maintain optimal health.Role of microRNAs in the regulation of drug metabolizing and transporting genes and the response to environmental toxicants.P-glycoprotein-mediated transcellular transport of MDR-reversing agents.Altered drug-stimulated ATPase activity in mutants of the human multidrug resistance protein.Association of MDR1 gene polymorphism (G2677T) with imatinib response in Egyptian chronic myeloid leukemia patients.Construction of a model cell line for the assay of MDR1 (multi drug resistance gene-1) substrates/inhibitors using HeLa cellsRole of multidrug resistance P-glycoprotein in the secretion of aldosterone by human adrenal NCI-H295 cells.Gene transfer of drug resistance genes. Implications for cancer therapy.Modulation of drug-stimulated ATPase activity of human MDR1/P-glycoprotein by cholesterolReporter dyes demonstrate functional expression of multidrug resistance proteins in the marine flatworm Macrostomum lignano: the sponge-derived dye Ageladine A is not a substrate of these transporters.A common P-glycoprotein polymorphism is associated with nortriptyline-induced postural hypotension in patients treated for major depression.Detection of multidrug resistance (MDR1) gene RNA expression in human tumors by a sensitive ribonuclease protection assay.Pilot study of MDR1 gene transfer into hematopoietic stem cells and chemoprotection in metastatic breast cancer patients.Genetic determinants of selective serotonin reuptake inhibitor related sexual dysfunction.ATP-binding cassette subfamily B member 1 1236C/T polymorphism significantly affects the therapeutic outcome of tacrolimus in patients with refractory ulcerative colitis.Functional expression of human P-glycoprotein in Schizosaccharomyces pombe.Identification of Residues in the Drug-binding Domain of Human P-glycoproteinMultidrug ResistanceAmino acid substitutions in the first transmembrane domain (TM1) of P-glycoprotein that alter substrate specificity
P2860
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P2860
P-glycoprotein gene (MDR1) cDNA from human adrenal: normal P-glycoprotein carries Gly185 with an altered pattern of multidrug resistance.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年学术文章
@wuu
1989年学术文章
@zh-cn
1989年学术文章
@zh-hans
1989年学术文章
@zh-my
1989年学术文章
@zh-sg
1989年學術文章
@yue
1989年學術文章
@zh
1989年學術文章
@zh-hant
name
P-glycoprotein gene (MDR1) cDN ...... ttern of multidrug resistance.
@en
P-glycoprotein gene
@nl
type
label
P-glycoprotein gene (MDR1) cDN ...... ttern of multidrug resistance.
@en
P-glycoprotein gene
@nl
prefLabel
P-glycoprotein gene (MDR1) cDN ...... ttern of multidrug resistance.
@en
P-glycoprotein gene
@nl
P2093
P1476
P-glycoprotein gene (MDR1) cDN ...... ttern of multidrug resistance.
@en
P2093
P304
P356
10.1016/0006-291X(89)91985-2
P407
P577
1989-07-01T00:00:00Z