CPP, a new potent and selective NMDA antagonist. Depression of central neuron responses, affinity for [3H]D-AP5 binding sites on brain membranes and anticonvulsant activity.
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Revisiting AMPA receptors as an antiepileptic drug target7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complexD-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptorGlutamate receptor ion channels: structure, regulation, and functionAgonist analysis of 2-(carboxycyclopropyl)glycine isomers for cloned metabotropic glutamate receptor subtypes expressed in Chinese hamster ovary cellsModulation of seizure susceptibility in the mouse by the strychnine-insensitive glycine recognition site of the NMDA receptor/ion channel complex.Effects of pharmacological manipulations of NMDA-receptors on deliberation in the Multiple-T task.Two classes of N-methyl-D-aspartate recognition sites: differential distribution and differential regulation by glycine.3H-labeled MK-801 binding to the excitatory amino acid receptor complex from rat brain is enhanced by glycineAn examination of NMDA receptor contribution to conditioned responding evoked by the conditional stimulus effects of nicotineCGP 37849 and CGP 39551: novel and potent competitive N-methyl-D-aspartate receptor antagonists with oral activityMeasurement of NMDA Receptor Antagonist, CPP, in Mouse Plasma and Brain Tissue Following Systematic Administration Using Ion-Pair LCMS/MSNew advances in NMDA receptor pharmacology.Evaluation of the sedative and anticonvulsant properties of three Cameroonian plants.A local circuit neocortical synapse that operates via both NMDA and non-NMDA receptors.Frequency-dependent associative long-term potentiation at the hippocampal mossy fiber-CA3 synapse.Functional NMDA receptors are expressed by both AII and A17 amacrine cells in the rod pathway of the mammalian retina.Dual regulation of NR2B and NR2C expression by NMDA receptor activation in mouse cerebellar granule cell culturesGlutamate Clearance Is Locally Modulated by Presynaptic Neuronal Activity in the Cerebral CortexCould the underestimation of bipolarity obstruct the search for novel antidepressant drugs?Autoreceptor regulation of glutamate and aspartate release from slices of the hippocampal CA1 area.Novel kainate derivatives: potent depolarizing actions on spinal motoneurones and dorsal root fibres in newborn ratsPotent NMDA-like actions and potentiation of glutamate responses by conformational variants of a glutamate analogue in the rat spinal cord.The pharmacological specificity of N-methyl-D-aspartate receptors in rat cerebral cortex: correspondence between radioligand binding and electrophysiological measurements.The expression of N-methyl-D-aspartate-receptor-mediated component during epileptiform synaptic activity in hippocampus.Participation of NMDA and non-NMDA excitatory amino acid receptors in the mediation of spinal reflex potentials in rats: an in vivo study.The anticonvulsant and behavioural profile of L-687,414, a partial agonist acting at the glycine modulatory site on the N-methyl-D-aspartate (NMDA) receptor complex.Excitatory amino acids in neonatal brain: contributions to pathology and therapeutic strategies.Stimulation of gamma-[3H]aminobutyric acid release from cultured mouse cerebral cortex neurons by sulphur-containing excitatory amino acid transmitter candidates: receptor activation mediates two distinct mechanisms of release.Inhibition of N-methyl-D-aspartate- and kainic acid-induced neurotransmitter release by omega-conotoxin GVIA.A comparison between the in vivo and in vitro activity of five potent and competitive NMDA antagonists.L-proline depolarizes rat spinal motoneurones by an excitatory amino acid antagonist-sensitive mechanism.The effects of cholinoceptor agonists and antagonists on C-fibre evoked responses in the substantia gelatinosa of neonatal rat spinal cord slices.Discrimination reversal conditioning of an eyeblink response is impaired by NMDA receptor blockade.Neuroactive sulphur amino acids evoke a calcium-dependent transmitter release from cultured neurones that is sensitive to excitatory amino acid receptor antagonists.Inactivation of amino acid receptors in medullary reticular formation modulates and suppresses ingestion and rejection responses in the awake rat.Selective excitotoxic pathology in the rat hippocampus.Localization of N-methyl-D-aspartate receptors in the rat striatum: effects of specific lesions on the [3H]3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid binding.Presynaptic glutamate receptors modulate dopamine release from striatal synaptosomes.Comparison of the pharmacological properties of GK11 and MK801, two NMDA receptor antagonists: towards an explanation for the lack of intrinsic neurotoxicity of GK11.
P2860
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P2860
CPP, a new potent and selective NMDA antagonist. Depression of central neuron responses, affinity for [3H]D-AP5 binding sites on brain membranes and anticonvulsant activity.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年学术文章
@wuu
1986年学术文章
@zh-cn
1986年学术文章
@zh-hans
1986年学术文章
@zh-my
1986年学术文章
@zh-sg
1986年學術文章
@yue
1986年學術文章
@zh
1986年學術文章
@zh-hant
name
CPP, a new potent and selectiv ...... s and anticonvulsant activity.
@en
CPP, a new potent and selectiv ...... s and anticonvulsant activity.
@nl
type
label
CPP, a new potent and selectiv ...... s and anticonvulsant activity.
@en
CPP, a new potent and selectiv ...... s and anticonvulsant activity.
@nl
prefLabel
CPP, a new potent and selectiv ...... s and anticonvulsant activity.
@en
CPP, a new potent and selectiv ...... s and anticonvulsant activity.
@nl
P2093
P1433
P1476
CPP, a new potent and selectiv ...... s and anticonvulsant activity.
@en
P2093
H J Olverman
J C Watkins
P L Herrling
P304
P356
10.1016/0006-8993(86)90127-7
P407
P577
1986-09-01T00:00:00Z