Role of ERAB/L-3-hydroxyacyl-coenzyme A dehydrogenase type II activity in Abeta-induced cytotoxicity.
about
Expanded substrate screenings of human and Drosophila type 10 17beta-hydroxysteroid dehydrogenases (HSDs) reveal multiple specificities in bile acid and steroid hormone metabolism: characterization of multifunctional 3alpha/7alpha/7beta/17beta/20betIntrinsic alcohol dehydrogenase and hydroxysteroid dehydrogenase activities of human mitochondrial short-chain L-3-hydroxyacyl-CoA dehydrogenase2-Methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency is caused by mutations in the HADH2 gene.Binding of amyloid beta-peptide to mitochondrial hydroxyacyl-CoA dehydrogenase (ERAB): regulation of an SDR enzyme activity with implications for apoptosis in Alzheimer's diseaseCharacterization and localization of human type10 17beta-hydroxysteroid dehydrogenaseEndophilin I expression is increased in the brains of Alzheimer disease patientsInhibition of the mitochondrial enzyme ABAD restores the amyloid-β-mediated deregulation of estradiolAlzPlatform: an Alzheimer's disease domain-specific chemogenomics knowledgebase for polypharmacology and target identification research.Amyloid and lipids in the pathology of Alzheimer disease.Cellular cofactors for amyloid beta-peptide-induced cell stress. Moving from cell culture to in vivo.Identification of human ABAD inhibitors for rescuing Aβ-mediated mitochondrial dysfunction.Physicochemical characteristics of soluble oligomeric Abeta and their pathologic role in Alzheimer's disease.Amyloid-Beta interaction with mitochondriaThe amyloid-β-SDR5C1(ABAD) interaction does not mediate a specific inhibition of mitochondrial RNase P.Overexpression of 17β-hydroxysteroid dehydrogenase type 10 increases pheochromocytoma cell growth and resistance to cell death.Determination of small molecule ABAD inhibitors crossing blood-brain barrier and pharmacokineticsInhibition of amyloid-beta (Abeta) peptide-binding alcohol dehydrogenase-Abeta interaction reduces Abeta accumulation and improves mitochondrial function in a mouse model of Alzheimer's diseaseMitochondrial dysfunction and Alzheimer's disease: role of amyloid-beta peptide alcohol dehydrogenase (ABAD).Expression of the oxygen-regulated protein ORP150 accelerates wound healing by modulating intracellular VEGF transport.Selective cytotoxicity of intracellular amyloid beta peptide1-42 through p53 and Bax in cultured primary human neurons.Is amyloid binding alcohol dehydrogenase a drug target for treating Alzheimer's disease?Amyloid-beta-induced mitochondrial dysfunction.RAGE is a key cellular target for Abeta-induced perturbation in Alzheimer's disease.The consequences of mitochondrial amyloid beta-peptide in Alzheimer's disease.HSD10 disease: clinical consequences of mutations in the HSD17B10 gene.Beta-amyloid oligomers: recent developments.Oligo(ethylene glycol) derivatives of thioflavin T as inhibitors of protein-amyloid interactions.Mitochondrial β-amyloid in Alzheimer's disease.Morphology-Specific Inhibition of β-Amyloid Aggregates by 17β-Hydroxysteroid Dehydrogenase Type 10.
P2860
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P2860
Role of ERAB/L-3-hydroxyacyl-coenzyme A dehydrogenase type II activity in Abeta-induced cytotoxicity.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Role of ERAB/L-3-hydroxyacyl-c ...... in Abeta-induced cytotoxicity.
@en
Role of ERAB/L-3-hydroxyacyl-c ...... in Abeta-induced cytotoxicity.
@nl
type
label
Role of ERAB/L-3-hydroxyacyl-c ...... in Abeta-induced cytotoxicity.
@en
Role of ERAB/L-3-hydroxyacyl-c ...... in Abeta-induced cytotoxicity.
@nl
prefLabel
Role of ERAB/L-3-hydroxyacyl-c ...... in Abeta-induced cytotoxicity.
@en
Role of ERAB/L-3-hydroxyacyl-c ...... in Abeta-induced cytotoxicity.
@nl
P2093
P2860
P356
P1476
Role of ERAB/L-3-hydroxyacyl-c ...... in Abeta-induced cytotoxicity.
@en
P2093
Al-Mohanna F
Collison K
P2860
P304
P356
10.1074/JBC.274.4.2145
P407
P577
1999-01-01T00:00:00Z