A null mutation in inositol polyphosphate 4-phosphatase type I causes selective neuronal loss in weeble mutant mice.
about
The type Ialpha inositol polyphosphate 4-phosphatase generates and terminates phosphoinositide 3-kinase signals on endosomes and the plasma membraneLoss of Vac14, a regulator of the signaling lipid phosphatidylinositol 3,5-bisphosphate, results in neurodegeneration in mice.Phosphoinositides: tiny lipids with giant impact on cell regulationThe inositol polyphosphate 5-phosphatase, PIPP, Is a novel regulator of phosphoinositide 3-kinase-dependent neurite elongation.Inositol polyphosphate 4-phosphatase B as a regulator of bone mass in mice and humansPatterned neuroprotection in the Inpp4a(wbl) mutant mouse cerebellum correlates with the expression of Eaat4Phosphoinositide phosphatases in cell biology and disease.The core FOXG1 syndrome phenotype consists of postnatal microcephaly, severe mental retardation, absent language, dyskinesia, and corpus callosum hypogenesis.Regulation of P-Rex1 by phosphatidylinositol (3,4,5)-trisphosphate and Gbetagamma subunits.Identification of inositol polyphosphate 4-phosphatase type II as a novel tumor resistance biomarker in human laryngeal cancer HEp-2 cellsA screen for novel phosphoinositide 3-kinase effector proteins.Modifier genes for mouse phosphatidylinositol transfer protein α (vibrator) that bypass juvenile lethality.Phosphoinositide phosphatases and disease.Phosphoinositide signaling disorders in human diseases.The structure of phosphoinositide phosphatases: Insights into substrate specificity and catalysis.An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway.Mutations in phosphoinositide metabolizing enzymes and human disease.Depletion of Inositol Polyphosphate 4-Phosphatase II Suppresses Callosal Axon Formation in the Developing Mice.The role of inositol polyphosphate 4-phosphatase 1 in platelet function using a weeble mouse model.Phosphoinositide 3-kinase and INPP4B in human breast cancer.The role of phosphoinositides in synapse function.Inositol lipid phosphatases in membrane trafficking and human disease.The extended human PTPome: a growing tyrosine phosphatase family.The control of phosphatidylinositol 3,4-bisphosphate concentrations by activation of the Src homology 2 domain containing inositol polyphosphate 5-phosphatase 2, SHIP2.Identification of Phosphorylation Consensus Sequences and Endogenous Neuronal Substrates of the Psychiatric Risk Kinase TNIK.The inositol metabolism pathway as a target for neuroprotective strategies.Hindbrain malformation and myoclonic seizures associated with a deleterious mutation in the INPP4A gene.The PtdIns(3,4)P(2) phosphatase INPP4A is a suppressor of excitotoxic neuronal death.Regulation of PI(3)K/Akt signalling and cellular transformation by inositol polyphosphate 4-phosphatase-1.Microarray analysis of gene expression in adult retinal ganglion cells.Deletion of Inpp5a causes ataxia and cerebellar degeneration in mice.A new trick of INPP4A: decreased expression of INPP4A in patients with temporal lobe epilepsy and pilocarpine-induced rat model.The Extended Family of Protein Tyrosine Phosphatases.Phosphatidylinositol 4-phosphatase type II is an erythropoietin-responsive gene.
P2860
Q24523405-E033527B-8ECE-4720-8EB0-7F395B4460ACQ24678783-7F9EE952-AC0E-420C-9B50-4346BCEA1084Q27012953-D963CDAA-2C98-4352-974C-4DCA9DAD67DDQ28583817-413BFCCC-605D-4E3C-8D56-EB643974365DQ28586887-0A6FD5EE-2773-493F-B131-9E955228DF38Q33518517-FD01AB3D-01F0-40F5-B2F0-24C354CDF201Q33862413-D73F5A1B-28F4-4B21-8B4C-21F15D8F4EFCQ33924011-226BDD4E-1936-4936-AD74-DFC285714C32Q34367882-CAC32F69-F0B4-435F-90A5-BA34ED31C738Q34380914-25D5CD1A-4AAE-42B0-A9D0-F9F1F27BF6CAQ34751632-59EB7FCD-C61F-4900-ADFC-6A0AE7023F77Q34760506-84586A99-D1C2-4361-9EF0-58EBBCC3158AQ34877679-84908625-ABF3-44EE-8299-DA1DCEBE0C99Q35163916-FBE14275-6322-4689-8554-CF76E8E74CA0Q35225936-A5951887-4D17-4BA6-8150-5CA86DAF1572Q36320962-3A07A83B-B15D-466E-826A-F85D700F71BAQ36402106-35CA787C-1BAE-4A77-BB64-D43B8AF0E1FBQ37027372-C8921039-4E5A-4634-AC51-EB3E29BF8F70Q37812674-A09414B6-40B6-4F17-9596-B15AE2768C68Q38095569-9757538C-6B12-43C5-BD2B-825671062561Q38220785-732C3FA8-CF76-421E-AC85-35CEAA545321Q38223317-1FCF17AC-C456-4306-A948-8109C6CF22F8Q38634867-2EE28C37-3ECD-449F-8F10-F13514771D28Q39252524-E133ECE1-4462-4507-8646-C172FF61971BQ40234126-D5E01881-171C-4703-B9F4-EB5A53BF3633Q41779887-B7875332-3D98-423D-A171-5DD4858EB443Q41929184-7DE5F3CE-7777-4F42-998E-85BDDEC0702DQ42171703-EDDD76B5-5F79-4A0B-A284-5D498BD74A7AQ43129377-7F686729-D06D-47ED-B6FA-417A45BD0C02Q46867326-BBE09223-EE12-4E74-A31E-4213D9D30C86Q48139971-7C3DE5DB-50EF-4FA5-BFF9-A0520A1D0C32Q48612850-FD4D7460-8674-4196-9263-AFC4BC95E9C6Q51577116-1C01DF54-30D7-4DAB-813D-361DAA367D76Q53353134-79C52664-27EF-4741-8FB4-14D57BF3B44F
P2860
A null mutation in inositol polyphosphate 4-phosphatase type I causes selective neuronal loss in weeble mutant mice.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
A null mutation in inositol po ...... al loss in weeble mutant mice.
@en
A null mutation in inositol po ...... al loss in weeble mutant mice.
@nl
type
label
A null mutation in inositol po ...... al loss in weeble mutant mice.
@en
A null mutation in inositol po ...... al loss in weeble mutant mice.
@nl
prefLabel
A null mutation in inositol po ...... al loss in weeble mutant mice.
@en
A null mutation in inositol po ...... al loss in weeble mutant mice.
@nl
P2093
P1433
P1476
A null mutation in inositol po ...... al loss in weeble mutant mice.
@en
P2093
L D Shultz
M E Legare
W N Frankel
P304
P356
10.1016/S0896-6273(01)00468-8
P407
P577
2001-10-01T00:00:00Z