Studies on the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: inhibition of NAD-linked substrate oxidation by its metabolite, 1-methyl-4-phenylpyridinium.
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Inhibition by dizocilpine (MK-801) of striatal dopamine release induced by MPTP and MPP+: possible action at the dopamine transporterRole for dopamine in malonate-induced damage in vivo in striatum and in vitro in mesencephalic culturesMitochondria: in sickness and in healthComplex I deficiency in Parkinson's disease frontal cortex.Mitochondrial dysfunction in idiopathic Parkinson disease.Role of mitochondrial dysfunction and dopamine-dependent oxidative stress in amphetamine-induced toxicity.Enhancement of L-3-hydroxybutyryl-CoA dehydrogenase activity and circulating ketone body levels by pantethine. Relevance to dopaminergic injury.Oxidative stress in skin fibroblasts cultures from patients with Parkinson's diseaseNeuromelanin in the human brain: a review and atlas of pigmented cells in the substantia nigra.Cytotoxic effects of repin, a principal sesquiterpene lactone of Russian knapweed.Distinct effects of rotenone, 1-methyl-4-phenylpyridinium and 6-hydroxydopamine on cellular bioenergetics and cell death.MPTP: an industrial chemical and contaminant of illicit narcotics stimulates a new era in research on Parkinson's disease.Traumatic brain injury and trichloroethylene exposure interact and produce functional, histological, and mitochondrial deficitsDelayed caffeine treatment prevents nigral dopamine neuron loss in a progressive rat model of Parkinson's diseaseD-beta-hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease.Striatal dysfunctions associated with mitochondrial DNA damage in dopaminergic neurons in a mouse model of Parkinson's diseaseThe DNA polymerase gamma Y955C disease variant associated with PEO and parkinsonism mediates the incorporation and translesion synthesis opposite 7,8-dihydro-8-oxo-2'-deoxyguanosine.Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism.The angiotensin converting enzyme inhibitor captopril protects nigrostriatal dopamine neurons in animal models of parkinsonismRole of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity.The MPTP story: MAO activates tetrahydropyridine derivatives to toxins causing parkinsonism.Is complex II involved in the inhibition of mitochondrial respiration by N-methyl-4-phenylpyridinium cation (MMP+) and N-methyl-beta-carbolines?Clues to the mechanism underlying dopamine cell death in Parkinson's diseaseUpregulation of sestrin-2 expression via P53 protects against 1-methyl-4-phenylpyridinium (MPP+) neurotoxicity.Pegylated granulocyte colony-stimulating factor conveys long-term neuroprotection and improves functional outcome in a model of Parkinson's disease.Membrane-permeable Bcl-xL prevents MPTP-induced dopaminergic neuronal loss in the substantia nigra.Cytochrome oxidase inhibition: a novel animal model of Alzheimer's disease.Ablation of serum response factor in dopaminergic neurons exacerbates susceptibility towards MPTP-induced oxidative stress.Dementia in Parkinson's disease is associated with enhanced mitochondrial complex I deficiency.Cytochrome oxidase deficiency in Alzheimer's disease.Parkinsonism in Inherited Metabolic Disorders: Key Considerations and Major FeaturesCooperative action of JNK and AKT/mTOR in 1-methyl-4-phenylpyridinium-induced autophagy of neuronal PC12 cells
P2860
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P2860
Studies on the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: inhibition of NAD-linked substrate oxidation by its metabolite, 1-methyl-4-phenylpyridinium.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年学术文章
@wuu
1986年学术文章
@zh
1986年学术文章
@zh-cn
1986年学术文章
@zh-hans
1986年学术文章
@zh-my
1986年学术文章
@zh-sg
1986年學術文章
@yue
1986年學術文章
@zh-hant
name
Studies on the neurotoxicity o ...... , 1-methyl-4-phenylpyridinium.
@en
Studies on the neurotoxicity o ...... , 1-methyl-4-phenylpyridinium.
@nl
type
label
Studies on the neurotoxicity o ...... , 1-methyl-4-phenylpyridinium.
@en
Studies on the neurotoxicity o ...... , 1-methyl-4-phenylpyridinium.
@nl
prefLabel
Studies on the neurotoxicity o ...... , 1-methyl-4-phenylpyridinium.
@en
Studies on the neurotoxicity o ...... , 1-methyl-4-phenylpyridinium.
@nl
P2093
P2860
P1476
Studies on the neurotoxicity o ...... , 1-methyl-4-phenylpyridinium.
@en
P2093
P2860
P304
P356
10.1111/J.1471-4159.1986.TB01768.X
P407
P577
1986-05-01T00:00:00Z