Pharmacophore-based virtual screening, molecular docking, molecular dynamics simulation, and biological evaluation for the discovery of novel BRD4 inhibitors.

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Pharmacophore-based virtual screening, molecular docking, molecular dynamics simulation, and biological evaluation for the discovery of novel BRD4 inhibitors.

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http://www.wikidata.org/entity/Q48355483

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2017 nî lūn-bûn

@nan

2017年の論文

@ja

2017年学术文章

@wuu

2017年学术文章

@zh

2017年学术文章

@zh-cn

2017年学术文章

@zh-hans

2017年学术文章

@zh-my

2017年学术文章

@zh-sg

2017年學術文章

@yue

2017年學術文章

@zh-hant

name

Pharmacophore-based virtual sc ...... very of novel BRD4 inhibitors.

@en

Pharmacophore-based virtual sc ...... very of novel BRD4 inhibitors.

@nl

type

Item

label

Pharmacophore-based virtual sc ...... very of novel BRD4 inhibitors.

@en

Pharmacophore-based virtual sc ...... very of novel BRD4 inhibitors.

@nl

prefLabel

Pharmacophore-based virtual sc ...... very of novel BRD4 inhibitors.

@en

Pharmacophore-based virtual sc ...... very of novel BRD4 inhibitors.

@nl

P1476

Pharmacophore-based virtual sc ...... overy of novel BRD4 inhibitors

@en

P2093

Chunlan Pu

http://www.w3.org/2001/XMLSchema#string

Jiang Luo

http://www.w3.org/2001/XMLSchema#string

Manzhou Hou

http://www.w3.org/2001/XMLSchema#string

Suke Lan

http://www.w3.org/2001/XMLSchema#string

Xueyan Hou

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P2860

Histone recognition and large-scale structural analysis of the human bromodomain family

Down-regulation of NF-κB transcriptional activity in HIV-associated kidney disease by BRD4 inhibition

Lysine acetylation: codified crosstalk with other posttranslational modifications

Suppression of inflammation by a synthetic histone mimic

Discovery and characterization of small molecule inhibitors of the BET family bromodomains

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

Identification of a Chemical Probe for Bromo and Extra C-Terminal Bromodomain Inhibition through Optimization of a Fragment-Derived Hit

Fragment-based discovery of bromodomain inhibitors part 1: inhibitor binding modes and implications for lead discovery

Optimization of 3,5-Dimethylisoxazole Derivatives as Potent Bromodomain Ligands

BET Inhibition Silences Expression of MYCN and BCL2 and Induces Cytotoxicity in Neuroblastoma Tumor Models

P304

478-490

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P31

scholarly article

P356

10.1111/CBDD.13109

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Guoyi Yan

Rui Li

P577

2017-10-09T00:00:00Z

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P698

28901664

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