about
Delirium is a strong risk factor for dementia in the oldest-old: a population-based cohort studyNon-steroidal anti-inflammatory drugs and cognitive function: are prostaglandins at the heart of cognitive impairment in dementia and delirium?Influence of enriched environment on viral encephalitis outcomes: behavioral and neuropathological changes in albino Swiss mice.In vivo modification of tRNA with an artificial nucleobase leads to full disease remission in an animal model of multiple sclerosis.Malaise in the water maze: untangling the effects of LPS and IL-1beta on learning and memory.Neuroinflammation in delirium: a postmortem case-control study.Atypical inflammation in the central nervous system in prion disease.Cerebrospinal fluid markers of neuroinflammation in delirium: a role for interleukin-1β in delirium after hip fractureWorsening cognitive impairment and neurodegenerative pathology progressively increase risk for deliriumEarly Hippocampal Synaptic Loss Precedes Neuronal Loss and Associates with Early Behavioural Deficits in Three Distinct Strains of Prion Disease.Cerebrospinal fluid interleukin-8 levels are higher in people with hip fracture with perioperative delirium than in controlsEndogenous IL-1 in cognitive function and anxiety: a study in IL-1RI-/- miceThe impact of systemic infection on the progression of neurodegenerative disease.Systemic inflammation induces acute working memory deficits in the primed brain: relevance for delirium.Systemic infection, interleukin 1beta, and cognitive decline in Alzheimer's disease.Astrocytes Are Primed by Chronic Neurodegeneration to Produce Exaggerated Chemokine and Cell Infiltration Responses to Acute Stimulation with the Cytokines IL-1β and TNF-α.Interdependent and independent roles of type I interferons and IL-6 in innate immune, neuroinflammatory and sickness behaviour responses to systemic poly I:C.Systemic challenge with the TLR3 agonist poly I:C induces amplified IFNalpha/beta and IL-1beta responses in the diseased brain and exacerbates chronic neurodegenerationDNA sensors are expressed in astrocytes and microglia in vitro and are upregulated during gliosis in neurodegenerative diseaseMicroglia in the degenerating brain are capable of phagocytosis of beads and of apoptotic cells, but do not efficiently remove PrPSc, even upon LPS stimulation.Hippocampal lesions can enhance discrimination learning despite normal sensitivity to interference from incidental information.At the centre of neuronal, synaptic and axonal pathology in murine prion disease: degeneration of neuroanatomically linked thalamic and brainstem nuclei.The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I InterferonsSystemic inflammation induces acute behavioral and cognitive changes and accelerates neurodegenerative disease.Cyclooxygenase-1-dependent prostaglandins mediate susceptibility to systemic inflammation-induced acute cognitive dysfunction.Unravelling the pathophysiology of delirium: a focus on the role of aberrant stress responsesNew horizons in the pathogenesis, assessment and management of delirium.Systemic TNF-α produces acute cognitive dysfunction and exaggerated sickness behavior when superimposed upon progressive neurodegeneration.Systemic inflammation and delirium: important co-factors in the progression of dementia.Microglia and neurodegeneration: the role of systemic inflammation.Co-morbidity and systemic inflammation as drivers of cognitive decline: new experimental models adopting a broader paradigm in dementia research.Association of Delirium With Cognitive Decline in Late Life: A Neuropathologic Study of 3 Population-Based Cohort Studies.Environmental influences on antibody-enhanced dengue disease outcomes.Sub-pyrogenic systemic inflammation impacts on brain and behavior, independent of cytokines.Low protein diet fed exclusively during mouse oocyte maturation leads to behavioural and cardiovascular abnormalities in offspring.Comparison of inflammatory and acute-phase responses in the brain and peripheral organs of the ME7 model of prion diseaseSynaptic changes characterize early behavioural signs in the ME7 model of murine prion disease.Neuropil and neuronal changes in hippocampal NADPH-diaphorase histochemistry in the ME7 model of murine prion disease.Correction: A Systematic Analysis of the Peripheral and CNS Effects of Systemic LPS, IL-1β, TNF-α and IL-6 Challenges in C57BL/6 Mice.TGFbeta1 regulates the inflammatory response during chronic neurodegeneration.
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Colm Cunningham
@ast
Colm Cunningham
@en
Colm Cunningham
@es
Colm Cunningham
@nl
Colm Cunningham
@sl
type
label
Colm Cunningham
@ast
Colm Cunningham
@en
Colm Cunningham
@es
Colm Cunningham
@nl
Colm Cunningham
@sl
prefLabel
Colm Cunningham
@ast
Colm Cunningham
@en
Colm Cunningham
@es
Colm Cunningham
@nl
Colm Cunningham
@sl
P1053
A-1743-2010
P106
P1153
7201736265
P21
P31
P3829
P496
0000-0003-1423-5209
P569
2000-01-01T00:00:00Z