Synaptic changes characterize early behavioural signs in the ME7 model of murine prion disease.
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Sustained translational repression by eIF2α-P mediates prion neurodegenerationInsights into Mechanisms of Chronic NeurodegenerationNon-steroidal anti-inflammatory drugs and cognitive function: are prostaglandins at the heart of cognitive impairment in dementia and delirium?Early mechanisms of pathobiology are revealed by transcriptional temporal dynamics in hippocampal CA1 neurons of prion infected miceAnti-prion activity of Brilliant Blue GMutant PrP suppresses glutamatergic neurotransmission in cerebellar granule neurons by impairing membrane delivery of VGCC α(2)δ-1 SubunitAmyloid oligomer neurotoxicity, calcium dysregulation, and lipid raftsEarly behavioral changes and quantitative analysis of neuropathological features in murine prion disease: stereological analysis in the albino Swiss mice model.Single treatment with RNAi against prion protein rescues early neuronal dysfunction and prolongs survival in mice with prion disease.A Drosophila model of GSS syndrome suggests defects in active zones are responsible for pathogenesis of GSS syndrome.RBM3 mediates structural plasticity and protective effects of cooling in neurodegeneration.Age and Environment Influences on Mouse Prion Disease Progression: Behavioral Changes and Morphometry and Stereology of Hippocampal Astrocytes.Sequestration of free cholesterol in cell membranes by prions correlates with cytoplasmic phospholipase A2 activationApolipoprotein E-mimetics inhibit neurodegeneration and restore cognitive functions in a transgenic Drosophila model of Alzheimer's diseaseMicroglia and the urokinase plasminogen activator receptor/uPA system in innate brain inflammation.Bax deletion prevents neuronal loss but not neurological symptoms in a transgenic model of inherited prion disease.Molecular structure of amyloid fibrils controls the relationship between fibrillar size and toxicity.Temporal dynamics of hippocampal neurogenesis in chronic neurodegeneration.Prion protein facilitates synaptic vesicle release by enhancing release probability.Subtype and regional-specific neuroinflammation in sporadic creutzfeldt-jakob disease.Deficiency of prion protein induces impaired autophagic flux in neurons.Morphological and functional abnormalities in mitochondria associated with synaptic degeneration in prion disease.A searchable cross-platform gene expression database reveals connections between drug treatments and disease.At the extreme end of the psychoneuroimmunological spectrum: delirium as a maladaptive sickness behaviour response.The role of activity in synaptic degeneration in a protein misfolding disease, prion diseaseCombining comparative proteomics and molecular genetics uncovers regulators of synaptic and axonal stability and degeneration in vivoThe intricate mechanisms of neurodegeneration in prion diseases.Worsening cognitive impairment and neurodegenerative pathology progressively increase risk for deliriumEarly Hippocampal Synaptic Loss Precedes Neuronal Loss and Associates with Early Behavioural Deficits in Three Distinct Strains of Prion Disease.Prion replication alters the distribution of synaptophysin and caveolin 1 in neuronal lipid rafts.Reduced expression of the presynaptic co-chaperone cysteine string protein alpha (CSPα) does not exacerbate experimentally-induced ME7 prion diseaseSystemic inflammation induces acute working memory deficits in the primed brain: relevance for delirium.T-Tau and P-Tau in Brain and Blood from Natural and Experimental Prion Diseases.Minocycline attenuates microglia activation and blocks the long-term epileptogenic effects of early-life seizures.Staying connected: synapses in Alzheimer disease.Assessing burrowing, nest construction, and hoarding in miceA Neuronal Culture System to Detect Prion Synaptotoxicity.Early Generation of New PrPSc on Blood Vessels after Brain Microinjection of Scrapie in MiceDistribution of Misfolded Prion Protein Seeding Activity Alone Does Not Predict Regions of Neurodegeneration.Sickness behavior induced by cisplatin chemotherapy and radiotherapy in a murine head and neck cancer model is associated with altered mitochondrial gene expression
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Synaptic changes characterize early behavioural signs in the ME7 model of murine prion disease.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Synaptic changes characterize ...... model of murine prion disease.
@en
Synaptic changes characterize ...... model of murine prion disease.
@nl
type
label
Synaptic changes characterize ...... model of murine prion disease.
@en
Synaptic changes characterize ...... model of murine prion disease.
@nl
prefLabel
Synaptic changes characterize ...... model of murine prion disease.
@en
Synaptic changes characterize ...... model of murine prion disease.
@nl
P2093
P2860
P50
P1476
Synaptic changes characterize ...... model of murine prion disease.
@en
P2093
P2860
P304
P356
10.1046/J.1460-9568.2003.02662.X
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P577
2003-05-01T00:00:00Z