NCX1 and NCX3: two new effectors of delayed preconditioning in brain ischemia.
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Ionic homeostasis in brain conditioningThe antiepileptic drug levetiracetam suppresses non-convulsive seizure activity and reduces ischemic brain damage in rats subjected to permanent middle cerebral artery occlusionKB-R7943 reduces 4-aminopyridine-induced epileptiform activity in adult rats after neuronal damage induced by neonatal monosodium glutamate treatment.Endoplasmic reticulum refilling and mitochondrial calcium extrusion promoted in neurons by NCX1 and NCX3 in ischemic preconditioning are determinant for neuroprotection.Involvement of the sodium-calcium exchanger 3 (NCX3) in ziram-induced calcium dysregulation and toxicity.Elevated mRNA-levels of distinct mitochondrial and plasma membrane Ca(2+) transporters in individual hypoglossal motor neurons of endstage SOD1 transgenic mice.MicroRNA-103-1 selectively downregulates brain NCX1 and its inhibition by anti-miRNA ameliorates stroke damage and neurological deficits.Na(+)/Ca(2+) exchanger 1 (NCX-1) mediates the anti-apoptotic effect of Akt1 in neonatal rat cardiomyocytes during ischemia/reperfusion.Development of a high-affinity peptide that prevents phospholemman (PLM) inhibition of the sodium/calcium exchanger 1 (NCX1).Neuroprotection in stroke: past, present, and future.Does Na⁺/Ca²⁺ exchanger, NCX, represent a new druggable target in stroke intervention?Recent structural and functional insights into the family of sodium calcium exchangers.The role of Na+/Ca2+ exchanger subtypes in neuronal ischemic injury.Novel Cellular Mechanisms for Neuroprotection in Ischemic Preconditioning: A View from Inside Organelles.Cerebral Ischemic Preconditioning: the Road So Far….NCX1 Exchanger Cooperates with Calretinin to Confer Preconditioning-Induced Tolerance Against Cerebral Ischemia in the Striatum.Neuronal NCX1 overexpression induces stroke resistance while knockout induces vulnerability via AktIschemic tolerance modulates TRAIL expression and its receptors and generates a neuroprotected phenotype.Ncx3 gene ablation impairs oligodendrocyte precursor response and increases susceptibility to experimental autoimmune encephalomyelitis.Transient reversal of the sodium/calcium exchanger boosts presynaptic calcium and synaptic transmission at a cerebellar synapse.Preconditioning, induced by sub-toxic dose of the neurotoxin L-BMAA, delays ALS progression in mice and prevents Na+/Ca2+ exchanger 3 downregulation.
P2860
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P2860
NCX1 and NCX3: two new effectors of delayed preconditioning in brain ischemia.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
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2011年學術文章
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2011年學術文章
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name
NCX1 and NCX3: two new effectors of delayed preconditioning in brain ischemia.
@en
NCX1 and NCX3: two new effectors of delayed preconditioning in brain ischemia.
@nl
type
label
NCX1 and NCX3: two new effectors of delayed preconditioning in brain ischemia.
@en
NCX1 and NCX3: two new effectors of delayed preconditioning in brain ischemia.
@nl
prefLabel
NCX1 and NCX3: two new effectors of delayed preconditioning in brain ischemia.
@en
NCX1 and NCX3: two new effectors of delayed preconditioning in brain ischemia.
@nl
P2093
P50
P1476
NCX1 and NCX3: two new effectors of delayed preconditioning in brain ischemia
@en
P2093
Antonio Vinciguerra
Elga Esposito
Gianfranco Di Renzo
Rossana Sirabella
P304
P356
10.1016/J.NBD.2011.10.007
P577
2011-10-17T00:00:00Z