Chemical synthesis and characterization of maurotoxin, a short scorpion toxin with four disulfide bridges that acts on K+ channels.
about
Mechanisms of maurotoxin action on Shaker potassium channels.K+ channels as targets for specific immunomodulationChemical synthesis and 1H-NMR 3D structure determination of AgTx2-MTX chimera, a new potential blocker for Kv1.2 channel, derived from MTX and AgTx2 scorpion toxinsComputational Studies of Venom Peptides Targeting Potassium ChannelsScorpion toxins specific for potassium (K+) channels: a historical overview of peptide bioengineeringStructural and functional consequences of the presence of a fourth disulfide bridge in the scorpion short toxins: Solution structure of the potassium channel inhibitor HsTX1Solution structure of Pi4, a short four-disulfide-bridged scorpion toxin specific of potassium channelsTamapin, a venom peptide from the Indian red scorpion (Mesobuthus tamulus) that targets small conductance Ca2+-activated K+ channels and afterhyperpolarization currents in central neuronsParameters affecting in vitro oxidation/folding of maurotoxin, a four-disulphide-bridged scorpion toxinEvolution of maurotoxin conformation and blocking efficacy towards Shaker B channels during the course of folding and oxidation in vitroDetermination of species-specific components in the venom of Parabuthus scorpions from southern Africa using matrix-assisted laser desorption time-of-flight mass spectrometry.Disulfide bridge reorganization induced by proline mutations in maurotoxin.Effect of Cu2+ on the oxidative folding of synthetic maurotoxin in vitro.Molecular and cellular basis of small--and intermediate-conductance, calcium-activated potassium channel function in the brain.Molecular diversity and functional evolution of scorpion potassium channel toxinsDifferential molecular information of maurotoxin peptide recognizing IK(Ca) and Kv1.2 channels explored by computational simulation.Chemical synthesis and characterization of maurocalcine, a scorpion toxin that activates Ca(2+) release channel/ryanodine receptors.Effect of maurotoxin, a four disulfide-bridged toxin from the chactoid scorpion Scorpio maurus, on Shaker K+ channels.An ERG channel inhibitor from the scorpion Buthus eupeus.Brownian dynamics simulations of the recognition of the scorpion toxin maurotoxin with the voltage-gated potassium ion channels.Diversity of folds in animal toxins acting on ion channels.Structural basis of the selective block of Kv1.2 by maurotoxin from computer simulationsVoltage-gated sodium channel modulation by scorpion alpha-toxins.The Lymphocyte Potassium Channels Kv1.3 and KCa3.1 as Targets for Immunosuppression.Therapeutic potential of KCa3.1 blockers: recent advances and promising trends.Effect of gating modifier toxins on membrane thickness: implications for toxin effect on gramicidin and mechanosensitive channels.K+ channel modulators for the treatment of neurological disorders and autoimmune diseasesIsolation and characterization of a high affinity peptide inhibitor of ClC-2 chloride channels.The K+ channels K(Ca)3.1 and K(v)1.3 as novel targets for asthma therapy.KCa3.1 Channel Modulators as Potential Therapeutic Compounds for Glioblastoma.Recombinant scorpion toxins: focus on four-disulfide peptide blockers of Kv1-channels.Evidence for domain-specific recognition of SK and Kv channels by MTX and HsTx1 scorpion toxins.The 'functional' dyad of scorpion toxin Pi1 is not itself a prerequisite for toxin binding to the voltage-gated Kv1.2 potassium channels.A four-disulphide-bridged toxin, with high affinity towards voltage-gated K+ channels, isolated from Heterometrus spinnifer (Scorpionidae) venom.Hemitoxin, the first potassium channel toxin from the venom of the Iranian scorpion Hemiscorpius lepturus.A maurotoxin with constrained standard disulfide bridging: innovative strategy of chemical synthesis, pharmacology, and docking on K+ channels.First chemical synthesis of a scorpion alpha-toxin affecting sodium channels: the Aah I toxin of Androctonus australis hector.Maurotoxin, a four disulfide bridge toxin from Scorpio maurus venom: purification, structure and action on potassium channels.Genomic organization of three neurotoxins active on small conductance Ca2+-activated potassium channels from the scorpion Buthus martensi Karsch.Chemical synthesis and characterization of Pi1, a scorpion toxin from Pandinus imperator active on K+ channels.
P2860
Q24537375-C58BF3AC-B952-4139-AA57-C475B4D59E61Q24648323-66377BAE-0E72-4B85-B468-810BB5887A1FQ24672213-203B96F6-A429-44E9-81FA-D047A67E562EQ26775013-B269BF9F-9D09-4738-A240-05F8969C3E46Q26853728-E371F0FC-427F-44E9-B4FB-FDCE3549FA2EQ27620963-BC189265-7F45-4B8B-8757-7EE04DB180AFQ27641880-A498E4D3-9793-463A-B901-2DECAD9E4808Q28202606-AF2EDEA7-E761-4523-ACA7-FEAC62BFEC65Q28349037-5C619A42-0DC0-42FF-92DC-7B4FB6FCB29CQ30790130-B748F149-44D4-4644-8751-D8B309E765FBQ30828841-75F03DC5-C858-48BE-9A2D-CCC06DE89587Q31877624-66CB9182-C2AD-462E-AA35-FC8D72F3D7CEQ33340790-CB1ED2F2-663D-4A04-B8AE-559AD9EC00DBQ33560844-4D7CDD5A-EBF7-4527-A884-6C035F9529BAQ33708620-AC8B8083-1A87-4C13-A7F9-763465441468Q33801747-5FAB13FE-EC50-4862-88AB-F12E1D9C1402Q33893060-4B451560-9959-4AD1-881E-84D96DAE2284Q33908835-26296701-E925-4047-95CB-6B7D34A2B812Q33929814-E4E8D724-A328-4B98-AFC7-81D723995F85Q34179045-D94463F4-510B-4FA5-9CD9-E3DB53BDE3BEQ34283547-F17C191F-080D-43D2-98E3-DF5EC169C3B3Q34448127-62204DD3-B0AD-40F2-8101-F55C533DF5E4Q34579624-A8F958E1-4C9D-4BEA-BF50-66F081FBF63FQ35660234-4E1202A7-A8F3-4E3B-81B0-3E5602CB621EQ35944615-D8E0ADA4-223D-4A7A-B798-C6E3D4F51552Q36807208-D56A8955-BF8D-49B9-BAA6-3D68EDF72C06Q37162392-5DB77180-E68E-4B98-94AB-C8EA31ECF37AQ37377743-327F2C4C-E212-4A38-A717-E3BCD32638E8Q37395286-8ABEF80C-C054-4ED7-8318-5FD50A0942EFQ39413648-748C48B8-8643-449B-AF89-50E96A61148DQ40063472-F7B7F9EA-93EE-4EAC-9A95-E75D803C2958Q40501290-563E9463-B677-49E3-BFA9-97E126DC6213Q41822903-D3A819F8-DBAE-48B1-B7BC-7CE778D4C196Q42159545-6CE56A41-A8EE-49DD-B15F-A41F303C6D7AQ42594510-91162FEE-8BC0-4098-88CD-7A916C4BF006Q44463878-F7B76F73-6C08-4F8E-913E-04E6CD340D3CQ45165703-12EAD98D-B12B-4856-8894-5E9697B68354Q46872933-C629B668-A9BE-4A20-9426-F6F7717B5035Q47952012-A1B977C9-4128-47D5-B8CD-C93D160DF862Q48886274-5865AF42-92EB-4880-9584-B45DA470F023
P2860
Chemical synthesis and characterization of maurotoxin, a short scorpion toxin with four disulfide bridges that acts on K+ channels.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh-hant
name
Chemical synthesis and charact ...... dges that acts on K+ channels.
@en
Chemical synthesis and charact ...... dges that acts on K+ channels.
@nl
type
label
Chemical synthesis and charact ...... dges that acts on K+ channels.
@en
Chemical synthesis and charact ...... dges that acts on K+ channels.
@nl
prefLabel
Chemical synthesis and charact ...... dges that acts on K+ channels.
@en
Chemical synthesis and charact ...... dges that acts on K+ channels.
@nl
P2093
P2860
P1433
P1476
Chemical synthesis and charact ...... idges that acts on K+ channels
@en
P2093
J Van Rietschoten
M F Martin-Eauclaire
R Oughideni
P2860
P304
P356
10.1111/J.1432-1033.1996.0491R.X
P407
P577
1996-12-01T00:00:00Z