A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis.
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A20 inhibits LUBAC-mediated NF-κB activation by binding linear polyubiquitin chains via its zinc finger 7Rheumatoid Arthritis: The Stride from Research to Clinical PracticeInterleukin-33 and Mast Cells Bridge Innate and Adaptive Immunity: From the Allergologist's PerspectiveT Cell Migration in Rheumatoid ArthritisRegulation of nuclear factor-κB in autoimmunityDeconstructing innate immune signaling in myelodysplastic syndromesUbiquitin in the immune systemDendritic cells: arbiters of immunity and immunological toleranceThe TLR and IL-1 signalling network at a glanceLessons from mathematically modeling the NF-κB pathway.Linear ubiquitination in immunityThe immunogenetics of Behçet's disease: A comprehensive reviewDoes antigen masking by ubiquitin chains protect from the development of autoimmune diseases?A20 deficiency causes spontaneous neuroinflammation in miceGenetics and epigenetics of rheumatoid arthritisrs10499194 polymorphism in the tumor necrosis factor-α inducible protein 3 (TNFAIP3) gene is associated with type-1 autoimmune hepatitis risk in Chinese Han population.Single nucleotide polymorphisms in TNFAIP3 were associated with the risks of rheumatoid arthritis in northern Chinese Han population.Alternative expression pattern of MALT1-A20-NF-κB in patients with rheumatoid arthritis.The tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20) imposes a brake on antitumor activity of CD8 T cellsNegative regulation of the NLRP3 inflammasome by A20 protects against arthritisA20 (Tnfaip3) deficiency in myeloid cells protects against influenza A virus infection.Dendritic cell maturation: functional specialization through signaling specificity and transcriptional programmingInterleukin-17 (IL-17)-induced microRNA 873 (miR-873) contributes to the pathogenesis of experimental autoimmune encephalomyelitis by targeting A20 ubiquitin-editing enzyme.Genetic association study of TNFAIP3, IFIH1, IRF5 polymorphisms with polymyositis/dermatomyositis in Chinese Han population.Intestinal epithelial expression of TNFAIP3 results in microbial invasion of the inner mucus layer and induces colitis in IL-10-deficient mice.Comprehensive microRNA analysis identifies miR-24 and miR-125a-5p as plasma biomarkers for rheumatoid arthritis.A20 restricts ubiquitination of pro-interleukin-1β protein complexes and suppresses NLRP3 inflammasome activity.Commensal microbiota contributes to chronic endocarditis in TAX1BP1 deficient mice.Measles contributes to rheumatoid arthritis: evidence from pathway and network analyses of genome-wide association studies.Lack of the ubiquitin-editing enzyme A20 results in loss of hematopoietic stem cell quiescenceThe ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosisMeta-analysis of the TNFAIP3 region in psoriasis reveals a risk haplotype that is distinct from other autoimmune diseasesInhibition of A20 expression in tumor microenvironment exerts anti-tumor effect through inducing myeloid-derived suppressor cells apoptosisAltered Methylation Profile of Lymphocytes Is Concordant with Perturbation of Lipids Metabolism and Inflammatory Response in Obesity.Negative regulation of TLR signaling in myeloid cells--implications for autoimmune diseases.Recruitment of A20 by the C-terminal domain of NEMO suppresses NF-κB activation and autoinflammatory disease.The Role of miRNAs in Cartilage Homeostasis.A20: linking a complex regulator of ubiquitylation to immunity and human diseaseLoss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory diseaseIntravenous Immunoglobulin (IVIG) Attenuates TNF-Induced Pathologic Bone Resorption and Suppresses Osteoclastogenesis by Inducing A20 Expression.
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P2860
A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis.
description
2011 nî lūn-bûn
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2011年の論文
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2011年学术文章
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2011年学术文章
@zh
2011年学术文章
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2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
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name
A20 (TNFAIP3) deficiency in my ...... sembling rheumatoid arthritis.
@en
type
label
A20 (TNFAIP3) deficiency in my ...... sembling rheumatoid arthritis.
@en
prefLabel
A20 (TNFAIP3) deficiency in my ...... sembling rheumatoid arthritis.
@en
P2093
P50
P356
P1433
P1476
A20 (TNFAIP3) deficiency in my ...... sembling rheumatoid arthritis.
@en
P2093
Bart N Lambrecht
Conor Mc Guire
Dirk Elewaut
Els Louagie
Eveline Verheugen
Geert van Loo
Lars Vereecke
Lies Geboes
Louis Boon
Marc Schmidt-Supprian
P2888
P304
P356
10.1038/NG.874
P407
P577
2011-08-14T00:00:00Z