Botulinum neurotoxin type C cleaves a single Lys-Ala bond within the carboxyl-terminal region of syntaxins. - Wikidata - wikimedia - TriplyDB

Botulinum neurotoxin type C cleaves a single Lys-Ala bond within the carboxyl-terminal region of syntaxins.

Botulinum neurotoxin type C cleaves a single Lys-Ala bond within the carboxyl-terminal region of syntaxins.

http://www.wikidata.org/entity/Q49164892

about

Novel isoform of syntaxin 1 is expressed in mammalian cells A novel tetanus neurotoxin-insensitive vesicle-associated membrane protein in SNARE complexes of the apical plasma membrane of epithelial cells The synaptic protein syntaxin1 is required for cellularization of Drosophila embryos Differential vesicular sorting of AMPA and GABAA receptors.The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites Syntaxin 13 is a developmentally regulated SNARE involved in neurite outgrowth and endosomal trafficking Protein kinase C and guanosine triphosphate combine to potentiate calcium-dependent membrane fusion driven by annexin 7 SNAREs in native plasma membranes are active and readily form core complexes with endogenous and exogenous SNAREs Proteolysis of SNAP-25 isoforms by botulinum neurotoxin types A, C, and E: domains and amino acid residues controlling the formation of enzyme-substrate complexes and cleavage Docking of secretory vesicles is syntaxin dependent.A mutation in the first intracellular loop of CACNA1A prevents P/Q channel modulation by SNARE proteins and lowers exocytosis.Differential interaction of tomosyn with syntaxin and SNAP25 depends on domains in the WD40 β-propeller core and determines its inhibitory activity.Botulinum neurotoxin D uses synaptic vesicle protein SV2 and gangliosides as receptors.Development of an in vitro bioassay for Clostridium botulinum type B neurotoxin in foods that is more sensitive than the mouse bioassay Botulinum neurotoxins and botulism: a novel therapeutic approach.Functional and physical coupling of voltage-sensitive calcium channels with exocytotic proteins: ramifications for the secretion mechanism.Syntaxin-3 and syntaxin-1A inhibit L-type calcium channel activity, insulin biosynthesis and exocytosis in beta-cell lines Cytotoxicity of botulinum neurotoxins reveals a direct role of syntaxin 1 and SNAP-25 in neuron survival.Therapeutic use of botulinum toxin in migraine: mechanisms of action.Small-molecule quinolinol inhibitor identified provides protection against BoNT/A in mice.Botulinum toxin: bioweapon & magic drug SNARE-catalyzed fusion events are regulated by Syntaxin1A-lipid interactions.Different substrate recognition requirements for cleavage of synaptobrevin-2 by Clostridium baratii and Clostridium botulinum type F neurotoxins.Type C botulinum toxin causes degeneration of motoneurons in vivo.Subunit vaccine efficacy against Botulinum neurotoxin subtypes.Detection of the HA-33 protein in botulinum neurotoxin type G complex by mass spectrometry.Functional interaction of syntaxin and SNAP-25 with voltage-sensitive L- and N-type Ca2+ channels.Functional characterization of botulinum neurotoxin serotype H as a hybrid of known serotypes F and A (BoNT F/A).SNAP-23 and syntaxin-2 localize to the extracellular surface of the platelet plasma membrane.Mass Spectrometric Identification and Differentiation of Botulinum Neurotoxins through Toxin Proteomics.Enhanced detection of type C botulinum neurotoxin by the Endopep-MS assay through optimization of peptide substrates Apical targeting of syntaxin 3 is essential for epithelial cell polarity.Calcium-regulated exocytosis is required for cell membrane resealing Ablation of S1P3 receptor protects mouse soleus from age-related drop in muscle mass, force, and regenerative capacity.Disruption of syntaxin-mediated protein interactions blocks neurotransmitter secretion.Progress in cell based assays for botulinum neurotoxin detection Block of transmitter release by botulinum C1 action on syntaxin at the squid giant synapse.Botulism diagnostics: from clinical symptoms to in vitro assays.The Caenorhabditis elegans unc-64 locus encodes a syntaxin that interacts genetically with synaptobrevin.Syntaxin is required for cell division

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P2860

Botulinum neurotoxin type C cleaves a single Lys-Ala bond within the carboxyl-terminal region of syntaxins.

http://www.wikidata.org/entity/Q49164892

description

1995 nî lūn-bûn

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1995年の論文

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1995年学术文章

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1995年学术文章

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1995年学术文章

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1995年学术文章

@zh-hans

1995年学术文章

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1995年学术文章

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1995年學術文章

@yue

1995年學術文章

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name

Botulinum neurotoxin type C cl ...... -terminal region of syntaxins.

@en

Botulinum neurotoxin type C cl ...... -terminal region of syntaxins.

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type

label

Botulinum neurotoxin type C cl ...... -terminal region of syntaxins.

@en

Botulinum neurotoxin type C cl ...... -terminal region of syntaxins.

@nl

prefLabel

Botulinum neurotoxin type C cl ...... -terminal region of syntaxins.

@en

Botulinum neurotoxin type C cl ...... -terminal region of syntaxins.

@nl

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Botulinum neurotoxin type C cl ...... -terminal region of syntaxins.

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C C Shone

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C Montecucco

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M K Bennett

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R H Scheller

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P2860

The syntaxin family of vesicular transport receptors

Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation

Structure of the catalytic domain of fibroblast collagenase complexed with an inhibitor

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

SNAP receptors implicated in vesicle targeting and fusion

Eukaryotic proteins expressed in Escherichia coli: an improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase

Syntaxin: a synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones

Protein-protein interactions contributing to the specificity of intracellular vesicular trafficking

Mechanism of action of tetanus and botulinum neurotoxins

Botulinum neurotoxins serotypes A and E cleave SNAP-25 at distinct COOH-terminal peptide bonds

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10566-10570

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18

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270

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Giampietro Schiavo

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1995-05-01T00:00:00Z

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7737992

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