Quaternary ammonium compounds as water channel blockers. Specificity, potency, and site of action. - Wikidata - wikimedia - TriplyDB

Quaternary ammonium compounds as water channel blockers. Specificity, potency, and site of action.

Quaternary ammonium compounds as water channel blockers. Specificity, potency, and site of action.

http://www.wikidata.org/entity/Q50114413

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Crystal structure of human aquaporin 4 at 1.8 A and its mechanism of conductance Detecting Aquaporin Function and Regulation Can Stabilization and Inhibition of Aquaporins Contribute to Future Development of Biomimetic Membranes?Disruption of ion homeostasis in the neurogliovascular unit underlies the pathogenesis of ischemic cerebral edema Aquaporin 1, a potential therapeutic target for migraine with aura A high throughput screen identifies chemical modulators of the laminin-induced clustering of dystroglycan and aquaporin-4 in primary astrocytes Fragment Screening of Human Aquaporin 1 Protonophore- and pH-insensitive glucose and sucrose accumulation detected by FRET nanosensors in Arabidopsis root tips Transgenic expression of AQP1 in the fiber cells of AQP0 knockout mouse: effects on lens transparency.Chondrocyte channel transcriptomics: do microarray data fit with expression and functional data?Automated cell-based assay for screening of aquaporin inhibitors.The potential roles of aquaporin 4 in malignant gliomas Aquaporins: important but elusive drug targets.Aquaporin-9 protein is the primary route of hepatocyte glycerol uptake for glycerol gluconeogenesis in mice The structural basis of water permeation and proton exclusion in aquaporins.Aquaporin water channel AgAQP1 in the malaria vector mosquito Anopheles gambiae during blood feeding and humidity adaptation Neuroprotective effect of aquaporin-4 deficiency in a mouse model of severe global cerebral ischemia produced by transient 4-vessel occlusion.Functional characterization of water transport and cellular localization of three aquaporin paralogs in the salmonid intestine.Rapid Identification of Novel Inhibitors of the Human Aquaporin-1 Water Channel.Experimental Evaluation of Proposed Small-Molecule Inhibitors of Water Channel Aquaporin-1 Comparative functional analysis of aquaporins/glyceroporins in mammals and anurans.Comparative efficacy of HgCl2 with candidate aquaporin-1 inhibitors DMSO, gold, TEA+ and acetazolamide.Aquaporins: a promising target for drug development.Auphen and dibutyryl cAMP suppress growth of hepatocellular carcinoma by regulating expression of aquaporins 3 and 9 in vivo.Cytotoxic edema: mechanisms of pathological cell swelling.Exploring transmembrane diffusion pathways with molecular dynamics Inhibition of AQP1 Hampers Osteosarcoma and Hepatocellular Carcinoma Progression Mediated by Bone Marrow-Derived Mesenchymal Stem Cells.Syntaxin specificity of aquaporins in the inner medullary collecting duct Is TEA an inhibitor for human Aquaporin-1?Cell volume regulation in chondrocytes.Aquaporins: New Targets for Cancer Therapy.Differential Inhibition of Water and Ion Channel Activities of Mammalian Aquaporin-1 by Two Structurally Related Bacopaside Compounds Derived from the Medicinal Plant Bacopa monnieri.Mercury inhibits the L170C mutant of aquaporin Z by making waters clog the water channel.Water permeability is a measure of severity in acute appendicitis.Placental programmed cell death: insights into the role of aquaporins.Inhibition of aquaporin-1 and aquaporin-4 water permeability by a derivative of the loop diuretic bumetanide acting at an internal pore-occluding binding site.Active movements in plants: Mechanism of trap closure by Dionaea muscipula Ellis.Aquaporin inhibition by gold(III) compounds: new insights.AQP4 expression in striatal primary cultures is regulated by dopamine--implications for proliferation of astrocytes.The aquaporin-4 water channel as a potential drug target in neurological disorders.

P2860

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P2860

Quaternary ammonium compounds as water channel blockers. Specificity, potency, and site of action.

http://www.wikidata.org/entity/Q50114413

description

2006 nî lūn-bûn

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2006年の論文

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2006年学术文章

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Quaternary ammonium compounds ...... , potency, and site of action.

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Quaternary ammonium compounds ...... , potency, and site of action.

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Quaternary ammonium compounds ...... , potency, and site of action.

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Quaternary ammonium compounds ...... , potency, and site of action.

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Quaternary ammonium compounds ...... , potency, and site of action.

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P2093

Andrew Hinton

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Bert L de Groot

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E Matthias Müller

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Frank J M Detmers

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Helmut Grubmüller

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Irene B M Konings

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Mozes Sze

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Peter M T Deen

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P2860

The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

Tetraethylammonium block of water flux in Aquaporin-1 channels expressed in kidney thin limbs of Henle's loop and a kidney-derived cell line

The human Aquaporin-5 gene. Molecular characterization and chromosomal localization

An aquaporin-2 water channel mutant which causes autosomal dominant nephrogenic diabetes insipidus is retained in the Golgi complex

Structural determinants of water permeation through aquaporin-1

Structure of a glycerol-conducting channel and the basis for its selectivity

Potassium channel receptor site for the inactivation gate and quaternary amine inhibitors

Structural basis of water-specific transport through the AQP1 water channel

Control of the selectivity of the aquaporin water channel family by global orientational tuning

WHAT IF: a molecular modeling and drug design program

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20

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281

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Sabine L. Flitsch

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2006-03-21T00:00:00Z

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16551622

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