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mutant RAS:GTP:p-RAF:MAP2Ks:MAPKs:scaffold proteinsmutant RAS:GTP:p-RAF:p-2S MAP2Ks:MAPKs:scaffold proteinshigh kinase activity BRAF mutants:scaffold:MAP2K:MAPK complexhigh kinase activity BRAF mutants:scaffold:p-2S MAP2K:MAPK complexRAS:GTP:moderate kinase activity p-RAF:MAP2Ks:MAPKs:scaffold proteinsRAS:GTP:moderate kinase activity p-RAF:p-2S MAP2Ks:MAPKs:scaffold proteinsRAS:GTP:inactive p-RAF:MAP2Ks:MAPKs:scaffold proteinsRAS:GTP: inactive p-RAF:p-2S MAP2Ks:MAPKs:scaffold proteinsp-BRAF/RAF fusion dimers:MAP2Ks:MAPKs:scaffold proteinsp-BRAF/RAF fusion dimers:p-2S MAP2Ks:MAPKs:scaffold proteinsActivated PAR1:Beta-arrestin-1:Src:ERKActivated PAR1:Beta-arrestin-2:Src:ERKActivated PAR1:Beta-arrestin-1:Activated Src:ERKAGER ligands:AGER:ERKactivated RAF:scaffold:MAP2K:MAPK complexactivated RAF:scaffold:p-2S MAP2K:MAPK complexWDR83:LAMTOR2:LAMTOR3:activated RAF:MAP2K:MAPK complexIL17RD:p-2S MAP2Ks:MAPKsMAPK monomers and dimersMutant RAS:p-RAF complexes bind MAP2Ks and MAPKsHigh kinase activity BRAF mutants bind MAP2Ks and MAPKsRAS:GTP:moderate kinase activity p-RAF complexes bind MAP2Ks and MAPKsRAS:GTP:p-RAF complexes paradoxically bind MAP2Ks and MAPKsp-BRAF and RAF fusion dimers bind MAP2Ks and MAPKsBeta-arrestin-1 acts as scaffold for a PAR1 signalling complexBeta-arrestin-2 acts as scaffold for a PAR1 signalling complexAGER binds ERK1/2MAP2Ks and MAPKs bind to the activated RAF complexWDR83:LAMTOR2:LAMTOR3 binds MAPK componentsIL17RD binds p-2S MAP2Ks and MAPKsLyn activates ERK
P527
Hypochoeris radicata attenuates LPS-induced inflammation by suppressing p38, ERK, and JNK phosphorylation in RAW 264.7 macrophages.Protective Effect of Phenolic Compounds Isolated from Mugwort () against Contrast-Induced Apoptosis in Kidney Epithelium Cell Line LLC-PK1Mitogen-Activated Protein Kinase Phosphatases (MKPs) in Fungal Signaling: Conservation, Function, and Regulation
P921
Q50256202-6683556E-A786-40A7-ABB8-8EDE1BE78595Q50256206-8C52387B-F126-419D-A238-1300EA268A8FQ50256223-58DBFB1C-8CC6-451B-98B6-F582BA344D04Q50256224-B2EA0486-62EA-4FE2-A51E-D4998550C471Q50256240-38DFDE02-E20B-4BA8-A17D-00C6E0359B4CQ50256241-D1698D4F-5B6D-421E-B1DC-05561EDBA073Q50256250-94740B3D-6949-4258-BB70-3C162064AEAFQ50256251-F1E5E355-C4FB-4ED8-8B73-7F30301B940DQ50256271-D0012177-71A5-4DCA-80C2-9FD5DD40BBC8Q50256272-87F40CAA-8E47-4B92-8716-7C55246FED3CQ50259034-BF9D2683-8677-4C7B-A4FA-D1EA8E7570E5Q50259036-ABA84D9A-D25C-4D9E-A309-BD846952E7A3Q50259037-0049203C-4119-4402-9B14-B5277F5CFFBDQ50261519-B31F598C-ECFD-4DE4-8C6A-1E907577924CQ50263685-520035F2-DB98-4483-99E7-E92A2EBE3C45Q50263688-695EA1FD-34AE-4B7D-A411-AA8FF091A920Q50263701-8C8D9EED-E037-41BA-9594-64C90D4CE3D1Q50263704-C07B86FF-036A-490D-B773-8338032C4F4DQ50263725-A9E99663-75B4-4A89-9647-4A9640DED22FQ50288914-078CC4C0-F6C2-4466-A43E-866EF2E37413Q50288920-CCB93F1B-D2BF-4F15-9D4A-83EF784F959CQ50288933-133BA647-A99A-413D-ACB4-A4EDA447CC08Q50288942-DD4D97B4-A99F-4789-BA3B-08755463B563Q50288949-05FE2854-44E1-4B6E-98AB-8D6B8F5C6EE9Q50291082-D554EF5C-EA04-415C-9A48-B7E90332B3AEQ50291083-66B1B637-3C53-4B94-83F8-AA7429C962D3Q50292003-37B3E3CD-8550-4016-8F47-A80F9CCD51D9Q50292933-D22A60EA-2A7C-4D62-8B82-67FDDBB42F61Q50292938-4868D27E-C5EB-4117-A901-97D322165A2EQ50292940-FDD7E8ED-32E6-48D5-89C0-1DE4E57932EDQ50293003-D589EEB5-4A88-4D8F-BF89-4E2EB031FA22
P527
description
Defined set from Reactome
@en
name
MAPKs
@en
type
label
MAPKs
@en
prefLabel
MAPKs
@en
P31
P3937
R-HSA-169291