p-BRAF and RAF fusion dimers bind MAP2Ks and MAPKs - Wikidata - wikimedia - TriplyDB

p-BRAF and RAF fusion dimers bind MAP2Ks and MAPKs

p-BRAF and RAF fusion dimers bind MAP2Ks and MAPKs

http://www.wikidata.org/entity/Q50288949

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Signaling by BRAF and RAF fusions

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p-BRAF and RAF fusion dimers bind MAP2Ks and MAPKs

http://www.wikidata.org/entity/Q50288949

description

An instance of the biological ...... P2Ks and MAPKs in Homo sapiens

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biologisch proces

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name

p-BRAF and RAF fusion dimers bind MAP2Ks and MAPKs

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type

label

p-BRAF and RAF fusion dimers bind MAP2Ks and MAPKs

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prefLabel

p-BRAF and RAF fusion dimers bind MAP2Ks and MAPKs

@en

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Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer.

BRAF fusions define a distinct molecular subset of melanomas with potential sensitivity to MEK inhibition

Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas

A novel SND1-BRAF fusion confers resistance to c-Met inhibitor PF-04217903 in GTL16 cells through [corrected] MAPK activation

Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma

The landscape of kinase fusions in cancer

Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas.

Identification of kinase fusion oncogenes in post-Chernobyl radiation-induced thyroid cancers.

Regulation of RAF protein kinases in ERK signalling.

Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma.

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reactome:R-HSA-6802934

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biological process

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Signaling by BRAF and RAF fusions

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R-HSA-6802934

http://www.w3.org/2001/XMLSchema#string

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MAP2K homo/heterodimers

RAF/MAPK scaffolds

p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1

p-BRAF/RAF fusion dimers

p-BRAF/RAF fusion dimers:MAP2Ks:MAPKs:scaffold proteins

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