Stimulation of IL8 transcription in senescent cells - Wikidata - wikimedia - TriplyDB

Stimulation of IL8 transcription in senescent cells

Stimulation of IL8 transcription in senescent cells

http://www.wikidata.org/entity/Q50286965

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Senescence-Associated Secretory Phenotype (SASP)

P527

Q45314181-4F4BF4F9-FB38-4A52-98F9-6D4263BB7FBA

P527

Stimulation of IL8 transcription in senescent cells

http://www.wikidata.org/entity/Q50286965

description

An instance of the biological ...... enescent cells in Homo sapiens

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biologisch proces

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name

Stimulation of IL8 transcription in senescent cells

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type

label

Stimulation of IL8 transcription in senescent cells

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prefLabel

Stimulation of IL8 transcription in senescent cells

@en

P2860

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Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network.

Chemokine signaling via the CXCR2 receptor reinforces senescence

Transcription factors NF-IL6 and NF-kappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8

Interleukin-1 alpha activates an NF-kappaB-like factor in osteoclast-like cells

NF-kappa B subunit-specific regulation of the interleukin-8 promoter

Distinct mechanisms for regulation of the interleukin-8 gene involve synergism and cooperativity between C/EBP and NF-kappa B

Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity

Cell surface-bound IL-1alpha is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network.

Interleukin 1alpha-induced NFkappaB activation and chemokine mRNA stabilization diverge at IRAK1

DNA damage signaling triggers degradation of histone methyltransferases through APC/C(Cdh1) in senescent cells.

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reactome:R-HSA-3790137

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biological process

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Senescence-Associated Secretory Phenotype (SASP)

P3937

R-HSA-3790137

http://www.w3.org/2001/XMLSchema#string

P527

C-X-C motif chemokine ligand 8

Cdh1:phospho-APC/C complex

p-T235;S321-CEBPB:NF-kB:IL8 Gene

P703