FEN1 cleaves displaced ssDNA flaps during MMEJ - Wikidata - wikimedia - TriplyDB

FEN1 cleaves displaced ssDNA flaps during MMEJ

FEN1 cleaves displaced ssDNA flaps during MMEJ

http://www.wikidata.org/entity/Q50287395

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HDR through MMEJ (alt-NHEJ)

P527

Q45314249-0134018F-7B4C-444E-AA7C-EFE97B7A3B98

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FEN1 cleaves displaced ssDNA flaps during MMEJ

http://www.wikidata.org/entity/Q50287395

description

An instance of the biological ...... ps during MMEJ in Homo sapiens

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biologisch proces

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name

FEN1 cleaves displaced ssDNA flaps during MMEJ

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type

label

FEN1 cleaves displaced ssDNA flaps during MMEJ

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prefLabel

FEN1 cleaves displaced ssDNA flaps during MMEJ

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Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ

Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1).

Homology and enzymatic requirements of microhomology-dependent alternative end joining

Modulation of DNA end joining by nuclear proteins

DNA polymerase beta and flap endonuclease 1 enzymatic specificities sustain DNA synthesis for long patch base excision repair.

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reactome:R-HSA-5687664

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biological process

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HDR through MMEJ (alt-NHEJ)

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R-HSA-5687664

http://www.w3.org/2001/XMLSchema#string

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Flap structure-specific endonuclease 1

Extended microhomologous 3'-ssDNA overhangs-flap-DSB:MRN:RBBP8:FEN1

Extended microhomologous 3'-ssDNA overhangs-DSB:MRN:RBBP8

P703