Homology and enzymatic requirements of microhomology-dependent alternative end joining
about
DNA Damage and Pulmonary HypertensionSnaps and mends: DNA breaks and chromosomal translocationsMicrohomology-mediated end joining is activated in irradiated human cells due to phosphorylation-dependent formation of the XRCC1 repair complex.DNA double-strand break repair in Penaeus monodon is predominantly dependent on homologous recombination.Induction of DNA damage and erroneous repair can explain genomic instability caused by endosulfan.Zinc finger nuclease-based double-strand breaks attenuate malaria parasites and reveal rare microhomology-mediated end joining.DNA polymerases δ and λ cooperate in repairing double-strand breaks by microhomology-mediated end-joining in Saccharomyces cerevisiaeMicrohomology-mediated end joining is the principal mediator of double-strand break repair during mitochondrial DNA lesionsLinking DNA polymerase theta structure and function in health and diseaseExpression of an Oncogenic BARD1 Splice Variant Impairs Homologous Recombination and Predicts Response to PARP-1 Inhibitor Therapy in Colon CancerA Novel Resveratrol Based Tubulin Inhibitor Induces Mitotic Arrest and Activates Apoptosis in Cancer Cells.Quantification of in vivo progenitor mutation accrual with ultra-low error rate and minimal input DNA using SIP-HAVA-seqAberrant DNA Double-strand Break Repair Threads in Breast Carcinoma: Orchestrating Genomic Insult Survival.Race-specific molecular alterations correlate with differential outcomes for black and white endometrioid endometrial cancer patients.Identification and characterization of novel ligase I inhibitors.Coordination of DNA single strand break repair.Drug-Driven Synthetic Lethality: Bypassing Tumor Cell Genetics with a Combination of AsiDNA and PARP InhibitorsHIV integrase inhibitor, Elvitegravir, impairs RAG functions and inhibits V(D)J recombination.HDR through MMEJ (alt-NHEJ)Secondary structure forming sequences drive SD-MMEJ repair of DNA double-strand breaks.Homologous recombination-mediated repair of DNA double-strand breaks operates in mammalian mitochondria.PARP1 or PARP2; FEN1 and POLQ are recruited to MMEJ siteFEN1 cleaves displaced ssDNA flaps during MMEJLIG3 ligates remaining SSBs in MMEJTargeting the MALAT1/PARP1/LIG3 complex induces DNA damage and apoptosis in multiple myeloma.The MRE11-RAD50-NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair.Kinetics and Fidelity of the Repair of Cas9-Induced Double-Strand DNA Breaks.PAM-OBG: A monoamine oxidase B specific prodrug that inhibits MGMT and generates DNA interstrand crosslinks, potentiating temozolomide and chemoradiation therapy in intracranial glioblastoma.Robust activation of microhomology-mediated end joining for precision gene editing applications
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P2860
Homology and enzymatic requirements of microhomology-dependent alternative end joining
description
2015 nî lūn-bûn
@nan
2015 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի մարտին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Homology and enzymatic requirements of microhomology-dependent alternative end joining
@ast
Homology and enzymatic requirements of microhomology-dependent alternative end joining
@en
Homology and enzymatic requirements of microhomology-dependent alternative end joining
@nl
type
label
Homology and enzymatic requirements of microhomology-dependent alternative end joining
@ast
Homology and enzymatic requirements of microhomology-dependent alternative end joining
@en
Homology and enzymatic requirements of microhomology-dependent alternative end joining
@nl
prefLabel
Homology and enzymatic requirements of microhomology-dependent alternative end joining
@ast
Homology and enzymatic requirements of microhomology-dependent alternative end joining
@en
Homology and enzymatic requirements of microhomology-dependent alternative end joining
@nl
P2093
P2860
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P356
P1476
Homology and enzymatic requirements of microhomology-dependent alternative end joining
@en
P2093
M Srivastava
S C Raghavan
S M Javadekar
P2860
P3181
P356
10.1038/CDDIS.2015.58
P407
P577
2015-03-19T00:00:00Z