Caspase-8 processing within TLR3 complex - Wikidata - wikimedia - TriplyDB

Caspase-8 processing within TLR3 complex

Caspase-8 processing within TLR3 complex

http://www.wikidata.org/entity/Q50291745

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TLR3-mediated TICAM1-dependent programmed cell death

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Caspase-8 processing within TLR3 complex

http://www.wikidata.org/entity/Q50291745

description

An instance of the biological ...... n TLR3 complex in Homo sapiens

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biologisch proces

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name

Caspase-8 processing within TLR3 complex

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type

label

Caspase-8 processing within TLR3 complex

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prefLabel

Caspase-8 processing within TLR3 complex

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cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms

Structural and biochemical studies on procaspase-8: new insights on initiator caspase activation

Insights into the regulatory mechanism for caspase-8 activation

Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif

Inducible dimerization and inducible cleavage reveal a requirement for both processes in caspase-8 activation.

dsRNA induces apoptosis through an atypical death complex associating TLR3 to caspase-8.

Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA.

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reactome:R-HSA-9013895

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apoptotic signaling pathway

biological process

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TLR3-mediated TICAM1-dependent programmed cell death

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R-HSA-9013895

http://www.w3.org/2001/XMLSchema#string

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activated TLR3:TRIF:RIP1:FADD:pro-caspase-8

activated TLR3:TRIF:RIP1:FADD

active caspase-8

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