SPOP:CUL3:RBX1 ubiquitinates GLI2;3 - Wikidata - wikimedia - TriplyDB

SPOP:CUL3:RBX1 ubiquitinates GLI2;3

SPOP:CUL3:RBX1 ubiquitinates GLI2;3

http://www.wikidata.org/entity/Q50298982

about

Hedgehog 'on' state

P527

Q45318278-79ABB63C-AABF-4A9A-BBCF-D18C299B706E

P527

SPOP:CUL3:RBX1 ubiquitinates GLI2;3

http://www.wikidata.org/entity/Q50298982

description

An instance of the biological ...... tinates GLI2;3 in Homo sapiens

@en

biologisch proces

@nl

name

SPOP:CUL3:RBX1 ubiquitinates GLI2;3

@en

type

label

SPOP:CUL3:RBX1 ubiquitinates GLI2;3

@en

prefLabel

SPOP:CUL3:RBX1 ubiquitinates GLI2;3

@en

P2860

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P2888

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P31

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P361

Q50298982-A4FDC7C8-EAB7-424E-B3E5-CE2621B25C22

P3937

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P527

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P703

Q50298982-72BF009C-4FF6-4BE3-B6A7-4BF17B3D3348

P2860

The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins

Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved

Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase

Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation.

A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes.

Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator.

Roadkill attenuates Hedgehog responses through degradation of Cubitus interruptus.

A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor.

P2888

reactome:R-HSA-5635856

P31

biological process

P361

Hedgehog 'on' state

P3937

R-HSA-5635856

http://www.w3.org/2001/XMLSchema#string

P527

2p-GLI:SPOP:CUL3:RBX1

ub-2p-GLI2;3:SPOP:CUL3:RBX1

P703