Operational definition of intrinsically unstructured protein sequences based on susceptibility to the 20S proteasome.
about
Improved disorder prediction by combination of orthogonal approachesClassification of intrinsically disordered regions and proteinsIdentification, analysis, and prediction of protein ubiquitination sitesPhysicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs)Wrecked regulation of intrinsically disordered proteins in diseases: pathogenicity of deregulated regulatorsDisordered proteinaceous machinesA decade and a half of protein intrinsic disorder: biology still waits for physicsReciprocal regulation of metabolic and signaling pathways.Time, space, and disorder in the expanding proteome universe.What's in a name? Why these proteins are intrinsically disordered: Why these proteins are intrinsically disordered.Describing sequence-ensemble relationships for intrinsically disordered proteins.Conserved RNA helicase FRH acts nonenzymatically to support the intrinsically disordered neurospora clock protein FRQ.Intrinsically disordered segments affect protein half-life in the cell and during evolution.Determinants of translation efficiency and accuracy.Proteasomes and protein conjugation across domains of life.Down-regulation of Cdx2 in colorectal carcinoma cells by the Raf-MEK-ERK 1/2 pathwayRegulation of cell division by intrinsically unstructured proteins: intrinsic flexibility, modularity, and signaling conduits.Nucleolar aggresomes as counterparts of cytoplasmic aggresomes in proteotoxic stress. Proteasome inhibitors induce nuclear ribonucleoprotein inclusions that accumulate several key factors of neurodegenerative diseases and cancer.Context-dependent resistance to proteolysis of intrinsically disordered proteins.Protein intrinsic disorder as a flexible armor and a weapon of HIV-1.Structural disorder and the loss of RNA homeostasis in aging and neurodegenerative disease.Functional properties and structural requirements of the plasmid pMV158-encoded MobM relaxase domain.Designing disorder: Tales of the unexpected tails.Rapid proteasomal degradation of posttranscriptional regulators of the TIS11/tristetraprolin family is induced by an intrinsically unstructured region independently of ubiquitination.The protein level of PGC-1α, a key metabolic regulator, is controlled by NADH-NQO1.S-palmitoylation of gamma-secretase subunits nicastrin and APH-1Biophysical characterization of the unstructured cytoplasmic domain of the human neuronal adhesion protein neuroligin 3.At the Interface of Three Nucleic Acids: The Role of RNA-Binding Proteins and Poly(ADP-ribose) in DNA Repair.Nonspecific yet decisive: Ubiquitination can affect the native-state dynamics of the modified protein.A mammalian nervous-system-specific plasma membrane proteasome complex that modulates neuronal function.The stability of the small nucleolar ribonucleoprotein (snoRNP) assembly protein Pih1 in Saccharomyces cerevisiae is modulated by its C terminus.Paradoxes and wonders of intrinsic disorder: Complexity of simplicity.c-Fos proteasomal degradation is activated by a default mechanism, and its regulation by NAD(P)H:quinone oxidoreductase 1 determines c-Fos serum response kinetics.Susceptibility of p53 unstructured N terminus to 20 S proteasomal degradation programs the stress response.The N-terminal cytoplasmic region of NCBE displays features of an intrinsic disordered structure and represents a novel target for specific drug screening.The nanny model for IDPs.Functional Analysis of Human Hub Proteins and Their Interactors Involved in the Intrinsic Disorder-Enriched Interactions.The roles of intrinsic disorder-based liquid-liquid phase transitions in the "Dr. Jekyll-Mr. Hyde" behavior of proteins involved in amyotrophic lateral sclerosis and frontotemporal lobar degeneration.Regulatory evolution through divergence of a phosphoswitch in the transcription factor CEBPB.Thermo-resistant intrinsically disordered proteins are efficient 20S proteasome substrates
P2860
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P2860
Operational definition of intrinsically unstructured protein sequences based on susceptibility to the 20S proteasome.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Operational definition of intr ...... ibility to the 20S proteasome.
@en
Operational definition of intr ...... ibility to the 20S proteasome.
@nl
type
label
Operational definition of intr ...... ibility to the 20S proteasome.
@en
Operational definition of intr ...... ibility to the 20S proteasome.
@nl
prefLabel
Operational definition of intr ...... ibility to the 20S proteasome.
@en
Operational definition of intr ...... ibility to the 20S proteasome.
@nl
P2093
P50
P356
P1433
P1476
Operational definition of intr ...... tibility to the 20S proteasome
@en
P2093
Israel Silman
Nina Reuven
Yosef Shaul
P304
P356
10.1002/PROT.21614
P407
P577
2008-03-01T00:00:00Z