Antisense Reduction of Mutant COMP Reduces Growth Plate Chondrocyte Pathology.

about

Novel therapeutic interventions for pseudoachondroplasia.Legionella Pneumophila and Dendrimers-Mediated Antisense Therapy.Mutant cartilage oligomeric matrix cartilage (COMP) compromises bone integrity, joint function and the balance between adipogenesis and osteogenesis.

P2860

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P2860

Antisense Reduction of Mutant COMP Reduces Growth Plate Chondrocyte Pathology.

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http://www.wikidata.org/entity/Q50322999

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2017 nî lūn-bûn

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2017年の論文

@ja

2017年学术文章

@wuu

2017年学术文章

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2017年学术文章

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2017年学术文章

@zh-hans

2017年学术文章

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2017年学术文章

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2017年學術文章

@yue

2017年學術文章

@zh-hant

name

Antisense Reduction of Mutant COMP Reduces Growth Plate Chondrocyte Pathology.

@en

Antisense Reduction of Mutant COMP Reduces Growth Plate Chondrocyte Pathology.

@nl

type

Item

label

Antisense Reduction of Mutant COMP Reduces Growth Plate Chondrocyte Pathology.

@en

Antisense Reduction of Mutant COMP Reduces Growth Plate Chondrocyte Pathology.

@nl

prefLabel

Antisense Reduction of Mutant COMP Reduces Growth Plate Chondrocyte Pathology.

@en

Antisense Reduction of Mutant COMP Reduces Growth Plate Chondrocyte Pathology.

@nl

P1476

Antisense Reduction of Mutant COMP Reduces Growth Plate Chondrocyte Pathology.

@en

P2093

Alka C Veerisetty

http://www.w3.org/2001/XMLSchema#string

Danielle Gattis

http://www.w3.org/2001/XMLSchema#string

Francoise Coustry

http://www.w3.org/2001/XMLSchema#string

Jacqueline T Hecht

http://www.w3.org/2001/XMLSchema#string

Joseph L Alcorn

http://www.w3.org/2001/XMLSchema#string

Karen L Posey

http://www.w3.org/2001/XMLSchema#string

Mohammad Hossain

http://www.w3.org/2001/XMLSchema#string

Punit P Seth

http://www.w3.org/2001/XMLSchema#string

Sheri Booten

http://www.w3.org/2001/XMLSchema#string

P2860

Cartilage oligomeric matrix protein is a calcium-binding protein, and a mutation in its type 3 repeats causes conformational changes

Mutations in cartilage oligomeric matrix protein causing pseudoachondroplasia and multiple epiphyseal dysplasia affect binding of calcium and collagen I, II, and IX

Interactions between the cartilage oligomeric matrix protein and matrilins. Implications for matrix assembly and the pathogenesis of chondrodysplasias

Pseudoachondroplasia and multiple epiphyseal dysplasia due to mutations in the cartilage oligomeric matrix protein gene

Cartilage oligomeric matrix protein-deficient mice have normal skeletal development.

Endoplasmic reticulum stress and the inflammatory basis of metabolic disease

A mouse model offers novel insights into the myopathy and tendinopathy often associated with pseudoachondroplasia and multiple epiphyseal dysplasia

Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C-terminal domain of COMP

Pseudoachondroplasia and multiple epiphyseal dysplasia: New etiologic developments

Characterization of cartilage oligomeric matrix protein (COMP) in human normal and pseudoachondroplasia musculoskeletal tissues

P304

705-714

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P31

scholarly article

P356

10.1016/J.YMTHE.2016.12.024

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P577

2017-02-03T00:00:00Z

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P698

28162960

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P932

5363192

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Antisense Reduction of Mutant COMP Reduces Growth Plate Chondrocyte Pathology.

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P2860

P2860

Antisense Reduction of Mutant COMP Reduces Growth Plate Chondrocyte Pathology.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P932