Mechanical stress activates xanthine oxidoreductase through MAP kinase-dependent pathways. - Wikidata - wikimedia - TriplyDB

Mechanical stress activates xanthine oxidoreductase through MAP kinase-dependent pathways.

Mechanical stress activates xanthine oxidoreductase through MAP kinase-dependent pathways.

http://www.wikidata.org/entity/Q50479892

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Mitogen-activated protein kinases regulate susceptibility to ventilator-induced lung injury Novel regulators of endothelial barrier function Uniaxial stretch-induced regulation of mitogen-activated protein kinase, Akt and p70 S6 kinase in the ageing Fischer 344 x Brown Norway rat aorta Induction of cellular antioxidant defense by amifostine improves ventilator-induced lung injury.Mitogen activated protein kinase activated protein kinase 2 regulates actin polymerization and vascular leak in ventilator associated lung injury Apocynin attenuates ventilator-induced lung injury in an isolated and perfused rat lung model.Myostatin augments muscle-specific ring finger protein-1 expression through an NF-kB independent mechanism in SMAD3 null muscle.Cyclic stretch, reactive oxygen species, and vascular remodeling.Paxillin mediates stretch-induced Rho signaling and endothelial permeability via assembly of paxillin-p42/44MAPK-GEF-H1 complex.Untargeted LC-MS metabolomics of bronchoalveolar lavage fluid differentiates acute respiratory distress syndrome from health.Inhaled activated protein C protects mice from ventilator-induced lung injury.Nitric oxide synthase 3 contributes to ventilator-induced lung injury.Using the one-lung method to link p38 to pro-inflammatory gene expression during overventilation in C57BL/6 and BALB/c mice Pre-treatment with allopurinol or uricase attenuates barrier dysfunction but not inflammation during murine ventilator-induced lung injury.Nox2-dependent glutathionylation of endothelial NOS leads to uncoupled superoxide production and endothelial barrier dysfunction in acute lung injury.Increased oxidative stress and cardiomyocyte myofibrillar degeneration in patients with chronic isolated mitral regurgitation and ejection fraction >60%.Mechanical ventilation enhances HMGB1 expression in an LPS-induced lung injury model.Role of shear stress and stretch in vascular mechanobiology.Cyclin-dependent kinase five mediates activation of lung xanthine oxidoreductase in response to hypoxia.Novel insights into interactions between mitochondria and xanthine oxidase in acute cardiac volume overload.Mitogen-activated protein kinase phosphatase-1 modulates regional effects of injurious mechanical ventilation in rodent lungs.The tyrosine kinase inhibitor imatinib prevents lung injury and death after intravenous LPS in mice.Activation of Vascular Endothelial Growth Factor (VEGF) Receptor 2 Mediates Endothelial Permeability Caused by Cyclic Stretch.Alveolar cell apoptosis is dependent on p38 MAP kinase-mediated activation of xanthine oxidoreductase in ventilator-induced lung injury Soluble guanylyl cyclase contributes to ventilator-induced lung injury in mice Chronic high-magnitude cyclic stretch stimulates EC inflammatory response via VEGF receptor 2-dependent mechanism.Perfusion-related stimuli for compensatory lung growth following pneumonectomy Activated protein C protects against ventilator-induced pulmonary capillary leak Defining a stimuli-response relationship in compensatory lung growth following major resection.Protective role of PI3-kinase/Akt/eNOS signaling in mechanical stress through inhibition of p38 mitogen-activated protein kinase in mouse lung Negative pressure pulmonary edema revisited: Pathophysiology and review of management.Dynamics of pulmonary endothelial barrier function in acute inflammation: mechanisms and therapeutic perspectives.Dispelling dogma and misconceptions regarding the most pharmacologically targetable source of reactive species in inflammatory disease, xanthine oxidoreductase.Alcohol Abuse is Associated with Enhanced Pulmonary and Systemic Xanthine Oxidoreductase Activity.Endothelial cell signaling and ventilator-induced lung injury: molecular mechanisms, genomic analyses, and therapeutic targets.Kinetic profiling of in vivo lung cellular inflammatory responses to mechanical ventilation.Xanthine oxidase and mitochondria contribute to vascular superoxide anion generation in DOCA-salt hypertensive rats.Ventilation with "clinically relevant" high tidal volumes does not promote stretch-induced injury in the lungs of healthy mice.XOR inhibition with febuxostat accelerates pulmonary endothelial barrier recovery and improves survival in lipopolysaccharide-induced murine sepsis.Increased p38 mitogen-activated protein kinase signaling is involved in the oxidative stress associated with oxygen and glucose deprivation in neonatal hippocampal slice cultures.

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Mechanical stress activates xanthine oxidoreductase through MAP kinase-dependent pathways.

http://www.wikidata.org/entity/Q50479892

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Mechanical stress activates xa ...... MAP kinase-dependent pathways.

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Mechanical stress activates xa ...... MAP kinase-dependent pathways.

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Mechanical stress activates xa ...... MAP kinase-dependent pathways.

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Mechanical stress activates xa ...... MAP kinase-dependent pathways.

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American Journal of Physiology - Lung Cellular and Molecular Physiology

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Mechanical stress activates xa ...... MAP kinase-dependent pathways.

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Emile J Hasan

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Eugenia J Han

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James E Watkins

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Jay H Finigan

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Joe G N Garcia

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Konstantin G Birukov

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Paul M Hassoun

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Raja-Elie E Abdulnour

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Rubin M Tuder

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Sekhar P Reddy

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P2860

The regulation of rat liver xanthine oxidase. Involvement of thiol groups in the conversion of the enzyme activity from dehydrogenase (type D) into oxidase (type O) and purification of the enzyme

Science review: mechanisms of ventilator-induced injury

Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network

Xanthine oxidoreductase is central to the evolution and function of the innate immune system

The acute respiratory distress syndrome

An increase in apparent affinity for sucrose of mung bean sucrose synthase is caused by in vitro phosphorylation or directed mutagenesis of Ser11.

Acute lung injury and acute respiratory distress syndrome. The clinical syndrome.

Structure and function of xanthine oxidoreductase: where are we now?

Role of the BMK1/ERK5 signaling pathway: lessons from knockout mice.

Oxygen-derived free radicals in postischemic tissue injury.

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