Irregular RNA splicing curtails postsynaptic gephyrin in the cornu ammonis of patients with epilepsy. - Wikidata - wikimedia - TriplyDB

Irregular RNA splicing curtails postsynaptic gephyrin in the cornu ammonis of patients with epilepsy.

Irregular RNA splicing curtails postsynaptic gephyrin in the cornu ammonis of patients with epilepsy.

http://www.wikidata.org/entity/Q50535323

about

Gephyrin, the enigmatic organizer at GABAergic synapses Identification of a new genomic hot spot of evolutionary diversification of protein function Human gephyrin is encompassed within giant functional noncoding yin-yang sequences Downregulation of gephyrin in temporal lobe epilepsy neurons in humans and a rat model Epilepsy caused by an abnormal alternative splicing with dosage effect of the SV2A gene in a chicken model Palmitoylation of gephyrin controls receptor clustering and plasticity of GABAergic synapses Simultaneous impairment of neuronal and metabolic function of mutated gephyrin in a patient with epileptic encephalopathy Gephyrin Cleavage in In Vitro Brain Ischemia Decreases GABAA Receptor Clustering and Contributes to Neuronal Death.The possible role of GABAA receptors and gephyrin in epileptogenesis.The relationship between genes affecting the development of epilepsy and approaches to epilepsy therapy.Presynaptic mechanisms of neuronal plasticity and their role in epilepsy.Gephyrin: a central GABAergic synapse organizer.Shutdown of achaete-scute homolog-1 expression by heterogeneous nuclear ribonucleoprotein (hnRNP)-A2/B1 in hypoxia.Electrophysiological Signature of Homomeric and Heteromeric Glycine Receptor Channels.Changes in neural network homeostasis trigger neuropsychiatric symptoms.Direct binding of GABAA receptor β2 and β3 subunits to gephyrin.Functional hallmarks of GABAergic synapse maturation and the diverse roles of neurotrophins.Experimental early-life febrile seizures induce changes in GABA(A) R-mediated neurotransmission in the dentate gyrus.Rare exonic deletions implicate the synaptic organizer Gephyrin (GPHN) in risk for autism, schizophrenia and seizures.Chloride transporter KCC2-dependent neuroprotection depends on the N-terminal protein domain.S-sulfocysteine/NMDA receptor-dependent signaling underlies neurodegeneration in molybdenum cofactor deficiency.Presence of ethanol-sensitive glycine receptors in medium spiny neurons in the mouse nucleus accumbens.

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P2860

Irregular RNA splicing curtails postsynaptic gephyrin in the cornu ammonis of patients with epilepsy.

http://www.wikidata.org/entity/Q50535323

description

2010 nî lūn-bûn

@nan

2010年の論文

@ja

2010年学术文章

@wuu

2010年学术文章

@zh

2010年学术文章

@zh-cn

2010年学术文章

@zh-hans

2010年学术文章

@zh-my

2010年学术文章

@zh-sg

2010年學術文章

@yue

2010年學術文章

@zh-hant

name

Irregular RNA splicing curtail ...... nis of patients with epilepsy.

@en

Irregular RNA splicing curtail ...... nis of patients with epilepsy.

@nl

type

label

Irregular RNA splicing curtail ...... nis of patients with epilepsy.

@en

Irregular RNA splicing curtail ...... nis of patients with epilepsy.

@nl

prefLabel

Irregular RNA splicing curtail ...... nis of patients with epilepsy.

@en

Irregular RNA splicing curtail ...... nis of patients with epilepsy.

@nl

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Irregular RNA splicing curtail ...... onis of patients with epilepsy

@en

P2093

Benjamin Förstera

http://www.w3.org/2001/XMLSchema#string

Carola Bernert

http://www.w3.org/2001/XMLSchema#string

Christoph Dehnicke

http://www.w3.org/2001/XMLSchema#string

Günter Schwarz

http://www.w3.org/2001/XMLSchema#string

Michael Tsokos

http://www.w3.org/2001/XMLSchema#string

Peter Horn

http://www.w3.org/2001/XMLSchema#string

Thomas-N Lehmann

http://www.w3.org/2001/XMLSchema#string

P2860

Mice with a targeted disruption of the Cl-/HCO3- exchanger AE3 display a reduced seizure threshold

A mutation in the gene for the neurotransmitter receptor-clustering protein gephyrin causes a novel form of molybdenum cofactor deficiency

The ubiquitin proteasome system in neuropathology

Identification of neuronal nuclei (NeuN) as Fox-3, a new member of the Fox-1 gene family of splicing factors

X-ray crystal structure of the trimeric N-terminal domain of gephyrin

Crystal structures of human gephyrin and plant Cnx1 G domains: comparative analysis and functional implications

Primary structure and alternative splice variants of gephyrin, a putative glycine receptor-tubulin linker protein

GABA: a pioneer transmitter that excites immature neurons and generates primitive oscillations

Gephyrin: where do we stand, where do we go?

Identification of a gephyrin binding motif on the glycine receptor beta subunit

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3778-3794

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scholarly article

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10.1093/BRAIN/AWQ298

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P407

P433

Pt 12

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133

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Jochen C. Meier

Abdel A. Belaidi

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2010-11-10T00:00:00Z

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47755331

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21071388

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