The anaphase-promoting complex/cyclosome inhibitor Emi2 is essential for meiotic but not mitotic cell cycles.
about
How eggs arrest at metaphase II: MPF stabilisation plus APC/C inhibition equals Cytostatic FactorTransmembrane signal transduction in oocyte maturation and fertilization: focusing on Xenopus laevis as a model animalFunctional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesisModulation of cell cycle control during oocyte-to-embryo transitionsThe zinc-binding region (ZBR) fragment of Emi2 can inhibit APC/C by targeting its association with the coactivator Cdc20 and UBE2C-mediated ubiquitylationStructural basis for recognition of Emi2 by Polo-like kinase 1 and development of peptidomimetics blocking oocyte maturation and fertilization.A dynamical model of oocyte maturation unveils precisely orchestrated meiotic decisions.The roles of Ca2+, downstream protein kinases, and oscillatory signaling in regulating fertilization and the activation of development.Mos in the oocyte: how to use MAPK independently of growth factors and transcription to control meiotic divisions.A zinc-dependent mechanism regulates meiotic progression in mammalian oocytesControl of Emi2 activity and stability through Mos-mediated recruitment of PP2A.New insight into metaphase arrest by cytostatic factor: from establishment to release.Cdc2 and Mos regulate Emi2 stability to promote the meiosis I-meiosis II transitionEmi2 inhibition of the anaphase-promoting complex/cyclosome absolutely requires Emi2 binding via the C-terminal RL tail.Delayed APC/C activation extends the first mitosis of mouse embryos.Aven is dynamically regulated during Xenopus oocyte maturation and is required for oocyte survival.Regulation of the action of early mitotic inhibitor 1 on the anaphase-promoting complex/cyclosome by cyclin-dependent kinases.Canonical and Alternative Pathways in Cyclin-Dependent Kinase 1/Cyclin B Inactivation upon M-Phase Exit in Xenopus laevis Cell-Free Extracts.The APC/C inhibitor XErp1/Emi2 is essential for Xenopus early embryonic divisions.
P2860
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P2860
The anaphase-promoting complex/cyclosome inhibitor Emi2 is essential for meiotic but not mitotic cell cycles.
description
2006 nî lūn-bûn
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2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
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2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
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2006年學術文章
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2006年學術文章
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name
The anaphase-promoting complex ...... c but not mitotic cell cycles.
@en
The anaphase-promoting complex ...... c but not mitotic cell cycles.
@nl
type
label
The anaphase-promoting complex ...... c but not mitotic cell cycles.
@en
The anaphase-promoting complex ...... c but not mitotic cell cycles.
@nl
prefLabel
The anaphase-promoting complex ...... c but not mitotic cell cycles.
@en
The anaphase-promoting complex ...... c but not mitotic cell cycles.
@nl
P2093
P2860
P356
P1476
The anaphase-promoting complex ...... c but not mitotic cell cycles.
@en
P2093
Andrea L Lewellyn
Bryn Grimison
James L Maller
Junjun Liu
P2860
P304
34736-34741
P356
10.1074/JBC.M606607200
P407
P577
2006-09-18T00:00:00Z