Conversion of the low affinity ouabain-binding site of non-gastric H,K-ATPase into a high affinity binding site by substitution of only five amino acids.
about
Analysis of the gastric H,K ATPase for ion pathways and inhibitor binding sites.Role of homologous ASP334 and GLU319 in human non-gastric H,K- and Na,K-ATPases in cardiac glycoside binding.Community-wide convergent evolution in insect adaptation to toxic cardenolides by substitutions in the Na,K-ATPase.A structural view on the functional importance of the sugar moiety and steroid hydroxyls of cardiotonic steroids in binding to Na,K-ATPase.Stepwise evolution of resistance to toxic cardenolides via genetic substitutions in the Na+/K+ -ATPase of milkweed butterflies (lepidoptera: Danaini).The fourth extracellular loop of the alpha subunit of Na,K-ATPase. Functional evidence for close proximity with the second extracellular loop.Gene duplications circumvent trade-offs in enzyme function: Insect adaptation to toxic host plants.Amphibian myiasis. Blowfly larvae (Lucilia bufonivora, Diptera: Calliphoridae) coping with the poisonous skin secretion of the common toad (Bufo bufo)
P2860
Q33723249-1500900E-4275-4CE3-945F-F59340495FCCQ36004623-76410AA7-091F-41C7-A847-73FDA7E2F965Q36167699-524549DE-4467-4147-9523-F09964166BB5Q41983671-E34B58DD-888A-4D2A-9459-1F93EFCD26A3Q42006681-F25620B2-9C08-4E1A-ABBF-ABE1A05CF54FQ46435887-5DB99E79-DF62-4A16-87DB-72F6D08C1A49Q51450873-7335E4EE-D6C2-41DA-8E57-FFE76383A786Q58836387-8D272660-F008-4AFB-8DBD-4687CEA77C6D
P2860
Conversion of the low affinity ouabain-binding site of non-gastric H,K-ATPase into a high affinity binding site by substitution of only five amino acids.
description
2006 nî lūn-bûn
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2006年の論文
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name
Conversion of the low affinity ...... tion of only five amino acids.
@en
Conversion of the low affinity ...... tion of only five amino acids.
@nl
type
label
Conversion of the low affinity ...... tion of only five amino acids.
@en
Conversion of the low affinity ...... tion of only five amino acids.
@nl
prefLabel
Conversion of the low affinity ...... tion of only five amino acids.
@en
Conversion of the low affinity ...... tion of only five amino acids.
@nl
P2093
P2860
P356
P1476
Conversion of the low affinity ...... tion of only five amino acids.
@en
P2093
Elisa C M Tonk
Herman G P Swarts
Jan B Koenderink
Jan Joep H H M De Pont
Li Yan Qiu
Peter H G M Willems
P2860
P304
13533-13539
P356
10.1074/JBC.M600551200
P407
P577
2006-03-10T00:00:00Z