Furin cleavage activates the epithelial Na+ channel by relieving Na+ self-inhibition. - Wikidata - wikimedia - TriplyDB

Furin cleavage activates the epithelial Na+ channel by relieving Na+ self-inhibition.

Furin cleavage activates the epithelial Na+ channel by relieving Na+ self-inhibition.

http://www.wikidata.org/entity/Q50653054

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Lipopolysaccharide hyperpolarizes guinea pig airway epithelium by increasing the activities of the epithelial Na+ channel and the Na+ - K+ pump Mutations in SPINT2 cause a syndromic form of congenital sodium diarrhea The Epithelial Sodium Channel and the Processes of Wound Healing CPT-cGMP Is A New Ligand of Epithelial Sodium Channels Epithelial Na(+) channel regulation by cytoplasmic and extracellular factors Regulation of αENaC transcription A long isoform of the epithelial sodium channel alpha subunit forms a highly active channel Epithelial sodium channel (ENaC) family: Phylogeny, structure-function, tissue distribution, and associated inherited diseases Identification of the roles of conserved charged residues in the extracellular domain of an epithelial sodium channel (ENaC) subunit by alanine mutagenesis Conserved charged residues at the surface and interface of epithelial sodium channel subunits--roles in cell surface expression and the sodium self-inhibition response Expression and purification of the alpha subunit of the epithelial sodium channel, ENaC.Plasmin activates epithelial Na+ channels by cleaving the gamma subunit.Constraint-based, homology model of the extracellular domain of the epithelial Na+ channel α subunit reveals a mechanism of channel activation by proteases.A segment of gamma ENaC mediates elastase activation of Na+ transport Cysteine palmitoylation of the γ subunit has a dominant role in modulating activity of the epithelial sodium channel Inhibition of lung fluid clearance and epithelial Na+ channels by chlorine, hypochlorous acid, and chloramines.New role for plasmin in sodium homeostasis.Extracellular allosteric regulatory subdomain within the gamma subunit of the epithelial Na+ channel.Role of epithelial sodium channels and their regulators in hypertension.Cys palmitoylation of the beta subunit modulates gating of the epithelial sodium channel Defining an inhibitory domain in the gamma subunit of the epithelial sodium channel Proteolytic activation of the epithelial sodium channel and therapeutic application of a serine protease inhibitor for the treatment of salt-sensitive hypertension.Allosteric inhibition of the epithelial Na+ channel through peptide binding at peripheral finger and thumb domains.Prostasin interacts with the epithelial Na+ channel and facilitates cleavage of the γ-subunit by a second protease Na+ inhibits the epithelial Na+ channel by binding to a site in an extracellular acidic cleft Base of the thumb domain modulates epithelial sodium channel gating.Second transmembrane domain modulates epithelial sodium channel gating in response to shear stress External Cu2+ inhibits human epithelial Na+ channels by binding at a subunit interface of extracellular domains.ENaC structure and function in the wake of a resolved structure of a family member.Sodium retention and volume expansion in nephrotic syndrome: implications for hypertension.TMPRSS4-dependent activation of the epithelial sodium channel requires cleavage of the γ-subunit distal to the furin cleavage site 8-(4-chlorophenylthio)-guanosine-3',5'-cyclic monophosphate-Na stimulates human alveolar fluid clearance by releasing external Na+ self-inhibition of epithelial Na+ channels Pendrin gene ablation alters ENaC subcellular distribution and open probability Extracellular finger domain modulates the response of the epithelial sodium channel to shear stress Functional Roles of Clusters of Hydrophobic and Polar Residues in the Epithelial Na+ Channel Knuckle Domain.Tissue kallikrein activation of the epithelial Na channel Acute downregulation of ENaC by EGF involves the PY motif and putative ERK phosphorylation site.Probing the structural basis of Zn2+ regulation of the epithelial Na+ channel.Role of epithelial sodium channels in the regulation of lung fluid homeostasis Regulation of transport in the connecting tubule and cortical collecting duct

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P2860

Furin cleavage activates the epithelial Na+ channel by relieving Na+ self-inhibition.

http://www.wikidata.org/entity/Q50653054

description

2006 nî lūn-bûn

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2006年の論文

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年學術文章

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2006年學術文章

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name

Furin cleavage activates the epithelial Na+ channel by relieving Na+ self-inhibition.

@en

Furin cleavage activates the epithelial Na+ channel by relieving Na+ self-inhibition.

@nl

type

label

Furin cleavage activates the epithelial Na+ channel by relieving Na+ self-inhibition.

@en

Furin cleavage activates the epithelial Na+ channel by relieving Na+ self-inhibition.

@nl

prefLabel

Furin cleavage activates the epithelial Na+ channel by relieving Na+ self-inhibition.

@en

Furin cleavage activates the epithelial Na+ channel by relieving Na+ self-inhibition.

@nl

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AJPRENAL.00439.2005

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American Journal of Physiology - Renal Physiology

P1476

Furin cleavage activates the epithelial Na+ channel by relieving Na+ self-inhibition.

@en

P2093

James B Bruns

http://www.w3.org/2001/XMLSchema#string

Marcelo D Carattino

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Rebecca P Hughey

http://www.w3.org/2001/XMLSchema#string

Thomas R Kleyman

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P2860

Epithelial sodium channel and the control of sodium balance: interaction between genetic and environmental factors

Epithelial sodium channel: a ligand-gated channel?

Epithelial Na+ channel subunit stoichiometry

Location of a ligand recognition site of FMRFamide-gated Na(+) channels.

The heterotetrameric architecture of the epithelial sodium channel (ENaC).

The epithelial Na+ channel: cell surface insertion and retrieval in Na+ homeostasis and hypertension.

Protons at the gate: DEG/ENaC ion channels help us feel and remember.

Epithelial sodium channel, salt intake, and hypertension.

New insights into epithelial sodium channel function in the kidney: site of action, regulation by ubiquitin ligases, serum- and glucocorticoid-inducible kinase and proteolysis.

Na self inhibition of human epithelial Na channel: temperature dependence and effect of extracellular proteases.

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F1488-96

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10.1152/AJPRENAL.00439.2005

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6

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290

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