Genome-wide DNA methylation analysis of articular chondrocytes identifies TRAF1, CTGF, and CX3CL1 genes as hypomethylated in osteoarthritis.

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CX3CL1 promotes MMP-3 production via the CX3CR1, c-Raf, MEK, ERK, and NF-κB signaling pathway in osteoarthritis synovial fibroblasts.

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Genome-wide DNA methylation analysis of articular chondrocytes identifies TRAF1, CTGF, and CX3CL1 genes as hypomethylated in osteoarthritis.

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Genome-wide DNA methylation an ...... omethylated in osteoarthritis.

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Genome-wide DNA methylation an ...... omethylated in osteoarthritis.

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Genome-wide DNA methylation an ...... omethylated in osteoarthritis.

@en

Genome-wide DNA methylation an ...... omethylated in osteoarthritis.

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Genome-wide DNA methylation an ...... omethylated in osteoarthritis.

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Genome-wide DNA methylation an ...... omethylated in osteoarthritis.

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Genome-wide DNA methylation an ...... omethylated in osteoarthritis.

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Chunmei Zhang

http://www.w3.org/2001/XMLSchema#string

Cibo Huang

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Like Zhao

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Qian Wang

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P2860

The role of CCN2 in cartilage and bone development

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Identification and initial characterization of 5000 expressed sequenced tags (ESTs) each from adult human normal and osteoarthritic cartilage cDNA libraries

The TNF-receptor-associated factor family: scaffold molecules for cytokine receptors, kinases and their regulators

CpG methylation regulates allelic expression of GDF5 by modulating binding of SP1 and SP3 repressor proteins to the osteoarthritis susceptibility SNP rs143383.

Connective tissue growth factor promotes articular damage by increased osteoclastogenesis in patients with rheumatoid arthritis.

Cartilage-specific over-expression of CCN family member 2/connective tissue growth factor (CCN2/CTGF) stimulates insulin-like growth factor expression and bone growth.

Characterization of the cartilage DNA methylome in knee and hip osteoarthritis

Epigenetic regulation of leptin affects MMP-13 expression in osteoarthritic chondrocytes: possible molecular target for osteoarthritis therapeutic intervention.

Regulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1β (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites.

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2335-2342

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scholarly article

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10.1007/S10067-017-3667-9

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2017-05-03T00:00:00Z

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28470428

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DNA methylation

Genome-wide DNA methylation analysis of articular chondrocytes identifies TRAF1, CTGF, and CX3CL1 genes as hypomethylated in osteoarthritis.

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P2860

P2860

Genome-wide DNA methylation analysis of articular chondrocytes identifies TRAF1, CTGF, and CX3CL1 genes as hypomethylated in osteoarthritis.

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P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P921

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P921