Lineage tracing evidence for in vitro dedifferentiation but rare proliferation of mouse pancreatic beta-cells.
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Epithelial-mesenchymal transition in cells expanded in vitro from lineage-traced adult human pancreatic beta cellsFrom Beta cell replacement to beta cell regeneration: implications for antidiabetic therapyConcise review: pancreas regeneration: recent advances and perspectivesAdult tissue sources for new β cells.Incomplete Re-Expression of Neuroendocrine Progenitor/Stem Cell Markers is a Key Feature of β-Cell Dedifferentiation.Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation.Analysis of beta-cell gene expression reveals inflammatory signaling and evidence of dedifferentiation following human islet isolation and cultureAdult stem cells as a renewable source of insulin-producing cellsReprogramming of pancreatic beta cells into induced pluripotent stem cellsHuman islet-derived precursor cells can cycle between epithelial clusters and mesenchymal phenotypes.Slow and steady is the key to beta-cell replication.Nkx6.1 is essential for maintaining the functional state of pancreatic beta cells.Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway.Why are levels of maternal microchimerism higher in type 1 diabetes pancreas?Enhanced rat islet function and survival in vitro using a biomimetic self-assembled nanomatrix gelOne process for pancreatic beta-cell coalescence into islets involves an epithelial-mesenchymal transition.β-Cell differentiation of human pancreatic duct-derived cells after in vitro expansionGlucose regulates cyclin D2 expression in quiescent and replicating pancreatic β-cells through glycolysis and calcium channelsDifferentiation of COPAS-sorted non-endocrine pancreatic cells into insulin-positive cells in the mouseTransplantation of heterospheroids of islet cells and mesenchymal stem cells for effective angiogenesis and antiapoptosis.Connective tissue growth factor modulates adult β-cell maturity and proliferation to promote β-cell regeneration in miceβ-Cell Generation: Can Rodent Studies Be Translated to Humans?Krüppel-Like Factor 4 Overexpression Initiates a Mesenchymal-to-Epithelial Transition and Redifferentiation of Human Pancreatic Cells following Expansion in Long Term Adherent Culture.Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure.PNA lectin for purifying mouse acinar cells from the inflamed pancreas.ActivinB Is Induced in Insulinoma To Promote Tumor Plasticity through a β-Cell-Induced Dedifferentiationβ-Cells are not generated in pancreatic duct ligation-induced injury in adult mice.Enhanced function of pancreatic islets co-encapsulated with ECM proteins and mesenchymal stromal cells in a silk hydrogel.Suppression of epithelial-to-mesenchymal transitioning enhances ex vivo reprogramming of human exocrine pancreatic tissue toward functional insulin-producing β-like cells.Neurogenin3 activation is not sufficient to direct duct-to-beta cell transdifferentiation in the adult pancreas.Beta-catenin signalling in mesenchymal islet-derived precursor cellsEx-vivo Expansion of Adult Human Pancreatic Beta-Cells.Beta Cell Regeneration in Adult Mice: Controversy Over the Involvement of Stem Cells.The use of stem cells for pancreatic regeneration in diabetes mellitus.Meta-analysis of gene expression in human pancreatic islets after in vitro expansion.A2A adenosine receptors control pancreatic dysfunction in high-fat-diet induced obesity.Insulin-positive, Glut2-low cells present within mouse pancreas exhibit lineage plasticity and are enriched within extra-islet endocrine cell clusters.Pancreatic β-cell identity in diabetes.A regulatory sequence from the retinoid X receptor γ gene directs expression to horizontal cells and photoreceptors in the embryonic chicken retina.Tracing phenotypic reversibility of pancreatic β-cells in vitro.
P2860
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P2860
Lineage tracing evidence for in vitro dedifferentiation but rare proliferation of mouse pancreatic beta-cells.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
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2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
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2007年學術文章
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name
Lineage tracing evidence for i ...... f mouse pancreatic beta-cells.
@en
Lineage tracing evidence for i ...... f mouse pancreatic beta-cells.
@nl
type
label
Lineage tracing evidence for i ...... f mouse pancreatic beta-cells.
@en
Lineage tracing evidence for i ...... f mouse pancreatic beta-cells.
@nl
prefLabel
Lineage tracing evidence for i ...... f mouse pancreatic beta-cells.
@en
Lineage tracing evidence for i ...... f mouse pancreatic beta-cells.
@nl
P2093
P356
P1433
P1476
Lineage tracing evidence for i ...... f mouse pancreatic beta-cells.
@en
P2093
Limor Ouziel-Yahalom
Noa Weinberg
Sarah Knoller
Shimon Efrat
P304
P356
10.2337/DB06-1654
P407
P577
2007-02-15T00:00:00Z