Histone H2A phosphorylation and H3 methylation are required for a novel Rad9 DSB repair function following checkpoint activation.
about
Epigenetic modifications in double-strand break DNA damage signaling and repairThe Dot1 histone methyltransferase and the Rad9 checkpoint adaptor contribute to cohesin-dependent double-strand break repair by sister chromatid recombination in Saccharomyces cerevisiaeMechanisms and regulation of mitotic recombination in Saccharomyces cerevisiaeDot1-dependent histone H3K79 methylation promotes activation of the Mek1 meiotic checkpoint effector kinase by regulating the Hop1 adaptorStructural and functional analysis of the Crb2-BRCT2 domain reveals distinct roles in checkpoint signaling and DNA damage repairRad9 BRCT domain interaction with phosphorylated H2AX regulates the G1 checkpoint in budding yeast.Saccharomyces cerevisiae Rif1 cooperates with MRX-Sae2 in promoting DNA-end resection.Phosphorylation of the budding yeast 9-1-1 complex is required for Dpb11 function in the full activation of the UV-induced DNA damage checkpoint.The Fun30 nucleosome remodeller promotes resection of DNA double-strand break ends.Yeast G1 DNA damage checkpoint regulation by H2A phosphorylation is independent of chromatin remodelingAssembly of Slx4 signaling complexes behind DNA replication forksSite-specific phosphorylation of the DNA damage response mediator rad9 by cyclin-dependent kinases regulates activation of checkpoint kinase 1Anc1, a protein associated with multiple transcription complexes, is involved in postreplication repair pathway in S. cerevisiae.Histone H3 K79 methylation states play distinct roles in UV-induced sister chromatid exchange and cell cycle checkpoint arrest in Saccharomyces cerevisiae.Colocalization of sensors is sufficient to activate the DNA damage checkpoint in the absence of damageDynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle-regulated by CDK1 activityProficient repair in chromatin remodeling defective ino80 mutants of Saccharomyces cerevisiae highlights replication defects as the main contributor to DNA damage sensitivityMaintenance of the DNA-damage checkpoint requires DNA-damage-induced mediator protein oligomerization.Rad9 interacts with Aft1 to facilitate genome surveillance in fragile genomic sites under non-DNA damage-inducing conditions in S. cerevisiaeHistone methyltransferase DOT1L drives recovery of gene expression after a genotoxic attack.A Rad53 independent function of Rad9 becomes crucial for genome maintenance in the absence of the Recq helicase Sgs1Mec1/ATR regulates the generation of single-stranded DNA that attenuates Tel1/ATM signaling at DNA ends.Ddc2 mediates Mec1 activation through a Ddc1- or Dpb11-independent mechanismCell biology of mitotic recombination.Interplay between histone H3 lysine 56 deacetylation and chromatin modifiers in response to DNA damage.Chromatin structure following UV-induced DNA damage-repair or death?Sae2 Function at DNA Double-Strand Breaks Is Bypassed by Dampening Tel1 or Rad53 ActivityIdentification of mutations that decrease the stability of a fragment of Saccharomyces cerevisiae chromosome III lacking efficient replicatorsTermination of Replication Stress Signaling via Concerted Action of the Slx4 Scaffold and the PP4 PhosphataseGammaH2AX and its role in DNA double-strand break repair.Dynamics of histone H2A, H4 and HS1ph during spermatogenesis with a focus on chromatin condensation and maturity of spermatozoa.An oligomerized 53BP1 tudor domain suffices for recognition of DNA double-strand breaks.Choreography of recombination proteins during the DNA damage response.Analysis of chromatin remodeling during formation of a DNA double-strand break at the yeast mating type locus.The histone methyltransferase Dot1/DOT1L as a critical regulator of the cell cycle.The diverse functions of Dot1 and H3K79 methylation.Biology of telomeres: lessons from budding yeast.Chromatin modifications and DNA repair: beyond double-strand breaks.Slx4 scaffolding in homologous recombination and checkpoint control: lessons from yeast.Biological function and regulation of histone and non-histone lysine methylation in response to DNA damage.
P2860
Q24607287-B0B2D2EC-8F39-4393-A3FB-FE7CD92A58A5Q24650576-2EC24CA1-4DEE-410E-8696-CD4C511887FFQ26864428-169F18C4-CDCA-400F-8ED8-7F08380C5064Q27324663-5CE6F754-B11E-4F90-A03D-0C2071891224Q27651403-10609815-BDF3-4CF4-BAC9-9B04217243A9Q27930415-702B5DDA-B205-4EA9-89D3-AD7AD3E6C63CQ27931587-6F2DC981-EA6C-4F9B-92F7-E0149103B45DQ27935850-E1C73FA8-DDD4-4A59-A277-DF970175D2D5Q27937088-9A5DD277-41FB-4723-BBA8-269A5721F550Q27938440-FECAD334-6836-41E9-B9FD-8818FE447454Q28608151-52BCFE15-DE18-40EA-8BA3-9ECAD1DCB975Q30419946-5B9F3A1C-789D-45FC-A8DF-78065C2B1ECFQ33384119-21623F90-6D4B-4330-AE06-913995BC453AQ33698485-29B9B74A-1DD6-4E91-A225-C10F17E969F8Q33888520-9FA33ACD-E791-4550-8F70-5BECE5343E5EQ34047330-85718BF2-AEF5-4760-B977-EF924439081AQ34088495-B1C4CBFB-E421-4B1F-B4F6-F555F4AB9959Q34369429-99626FD7-91EF-4CDE-8922-A27BBA14D4BEQ34489676-274DB5C0-81E9-48F4-B717-CD62017C64CAQ34825059-421466EC-8D0B-44AC-B429-CE2C08C32851Q35053821-E22E48BA-3394-47CA-8AB1-6A42AE796BABQ35072400-1515B8A8-82FE-48B6-9443-27F8F25A69CEQ35105714-FE04327F-067A-49A9-A904-270703A8AD47Q35164329-0C8D44EC-4650-46C5-9DB0-49F9E0E45E2CQ35579790-B2F28A65-9696-4952-A31B-249DBE559F98Q35600207-A88EFF61-C8D7-4100-9A0B-820C086F2776Q35846212-65CEB3DB-75BC-466D-BBAC-C55C8A27D9E2Q36287883-2B45B2FA-F52B-44FE-B657-B560EA286590Q36291440-45F91090-CE3B-4B19-86B6-159333C7E1E9Q36579390-C9744E8E-292B-499D-B2C4-A983BF98A1B7Q36845861-CB47F9AB-B000-415A-8216-27B03AF10C2CQ37099895-1118109F-E4B8-423B-96E8-2553AC65D767Q37310881-CF44CB16-B70E-4275-8290-212E0DF9A40DQ37401963-D49D53A6-CAF3-4D79-B827-E50A8C00B5D9Q37692579-35C21780-D98F-4ACA-9AFA-1207B8D3A081Q37897061-E88BA2D5-F722-4E39-894D-39E4F0218B63Q38206208-49545E38-FA53-4594-8A94-9870A1A59FDAQ38253643-EBC9EF4F-19E8-45E0-BD1D-DDEBC9FAD206Q38831197-1231DFDE-8041-4A56-9E7E-368DCE737B16Q38842748-EC1DEF83-7568-4B9F-B2B0-C37B0569F412
P2860
Histone H2A phosphorylation and H3 methylation are required for a novel Rad9 DSB repair function following checkpoint activation.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Histone H2A phosphorylation an ...... llowing checkpoint activation.
@en
Histone H2A phosphorylation an ...... llowing checkpoint activation.
@nl
type
label
Histone H2A phosphorylation an ...... llowing checkpoint activation.
@en
Histone H2A phosphorylation an ...... llowing checkpoint activation.
@nl
prefLabel
Histone H2A phosphorylation an ...... llowing checkpoint activation.
@en
Histone H2A phosphorylation an ...... llowing checkpoint activation.
@nl
P2093
P50
P1433
P1476
Histone H2A phosphorylation an ...... llowing checkpoint activation.
@en
P2093
Aisling M O'Shaughnessy
Anne O'Rorke
Geraldine W-L Toh
Stefano Maffini
P304
P356
10.1016/J.DNAREP.2006.03.005
P577
2006-05-02T00:00:00Z