Modulation of biogenesis of the Francisella tularensis subsp. novicida-containing phagosome in quiescent human macrophages and its maturation into a phagolysosome upon activation by IFN-gamma.
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Modulation of Host miRNAs by Intracellular Bacterial PathogensSubversion of host recognition and defense systems by Francisella sppMicroarray analysis of human monocytes infected with Francisella tularensis identifies new targets of host response subversionEvasion of IFN-γ signaling by Francisella novicida is dependent upon Francisella outer membrane protein CStructure-Function Analysis of DipA, a Francisella tularensis Virulence Factor Required for Intracellular ReplicationIdentification of an essential Francisella tularensis subsp. tularensis virulence factor.Francisella tularensis subsp. tularensis Schu S4 disulfide bond formation protein B, but not an RND-type efflux pump, is required for virulenceIdentification of transposon insertion mutants of Francisella tularensis tularensis strain Schu S4 deficient in intracellular replication in the hepatic cell line HepG2.Identification of an immune-regulated phagosomal Rab cascade in macrophages.Akt and SHIP modulate Francisella escape from the phagosome and induction of the Fas-mediated death pathway.Macrophage pro-inflammatory response to Francisella novicida infection is regulated by SHIP.A comprehensive transposon mutant library of Francisella novicida, a bioweapon surrogateThe Francisella pathogenicity island protein IglA localizes to the bacterial cytoplasm and is needed for intracellular growthIdentification of fevR, a novel regulator of virulence gene expression in Francisella novicida.The Fischer 344 rat reflects human susceptibility to francisella pulmonary challenge and provides a new platform for virulence and protection studiesAcid phosphatases do not contribute to the pathogenesis of type A Francisella tularensis.Molecular bases of proliferation of Francisella tularensis in arthropod vectors.Molecular complexity orchestrates modulation of phagosome biogenesis and escape to the cytosol of macrophages by Francisella tularensisHost factors required for modulation of phagosome biogenesis and proliferation of Francisella tularensis within the cytosol.Francisella tularensis T-cell antigen identification using humanized HLA-DR4 transgenic mice.Isolation of F. novicida-Containing Phagosome from Infected Human Monocyte Derived Macrophages.EmrA1 membrane fusion protein of Francisella tularensis LVS is required for resistance to oxidative stress, intramacrophage survival and virulence in mice.A Francisella novicida pdpA mutant exhibits limited intracellular replication and remains associated with the lysosomal marker LAMP-1Restricted cytosolic growth of Francisella tularensis subsp. tularensis by IFN-gamma activation of macrophagesIglC and PdpA are important for promoting Francisella invasion and intracellular growth in epithelial cellsGenome-wide RNAi screen in IFN-γ-treated human macrophages identifies genes mediating resistance to the intracellular pathogen Francisella tularensis.Francisella acid phosphatases inactivate the NADPH oxidase in human phagocytes.Generation of a convalescent model of virulent Francisella tularensis infection for assessment of host requirements for survival of tularemiaIdentification of mechanisms for attenuation of the FSC043 mutant of Francisella tularensis SCHU S4.Unique substrates secreted by the type VI secretion system of Francisella tularensis during intramacrophage infection.Intranasal vaccination with a defined attenuated Francisella novicida strain induces gamma interferon-dependent antibody-mediated protection against tularemia.Glycogen synthase kinase-3beta (GSK3beta) inhibition suppresses the inflammatory response to Francisella infection and protects against tularemia in miceType A Francisella tularensis acid phosphatases contribute to pathogenesis.Nitric oxide-mediated intracellular growth restriction of pathogenic Rhodococcus equi can be prevented by iron.Use of a capture-based pathogen transcript enrichment strategy for RNA-Seq analysis of the Francisella tularensis LVS transcriptome during infection of murine macrophages.Innate immune recognition of francisella tularensis: activation of type-I interferons and the inflammasomeFrancisella-arthropod vector interaction and its role in patho-adaptation to infect mammalsThe francisella intracellular life cycle: toward molecular mechanisms of intracellular survival and proliferation.Phagocytic receptors dictate phagosomal escape and intracellular proliferation of Francisella tularensis.Autophagy-mediated reentry of Francisella tularensis into the endocytic compartment after cytoplasmic replication.
P2860
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P2860
Modulation of biogenesis of the Francisella tularensis subsp. novicida-containing phagosome in quiescent human macrophages and its maturation into a phagolysosome upon activation by IFN-gamma.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Modulation of biogenesis of th ...... upon activation by IFN-gamma.
@en
Modulation of biogenesis of th ...... upon activation by IFN-gamma.
@nl
type
label
Modulation of biogenesis of th ...... upon activation by IFN-gamma.
@en
Modulation of biogenesis of th ...... upon activation by IFN-gamma.
@nl
prefLabel
Modulation of biogenesis of th ...... upon activation by IFN-gamma.
@en
Modulation of biogenesis of th ...... upon activation by IFN-gamma.
@nl
P2093
P1476
Modulation of biogenesis of th ...... upon activation by IFN-gamma.
@en
P2093
Maelle Molmeret
Marina Santic
Yousef Abu Kwaik
P304
P356
10.1111/J.1462-5822.2005.00529.X
P577
2005-07-01T00:00:00Z