BH3 domains other than Bim and Bid can directly activate Bax/Bak
about
Noxa/Bcl-2 protein interactions contribute to bortezomib resistance in human lymphoid cellsBID-induced structural changes in BAK promote apoptosisMitochondrial apoptosis and BH3 mimeticsBuilding blocks of the apoptotic pore: how Bax and Bak are activated and oligomerize during apoptosisBax activation initiates the assembly of a multimeric catalyst that facilitates Bax pore formation in mitochondrial outer membranesHypoxia-induced modulation of apoptosis and BCL-2 family proteins in different cancer cell typesBmf upregulation through the AMP-activated protein kinase pathway may protect the brain from seizure-induced cell death.Virtual screening for potential inhibitors of Mcl-1 conformations sampled by normal modes, molecular dynamics, and nuclear magnetic resonance.The rheostat in the membrane: BCL-2 family proteins and apoptosisMutual regulation of Bcl-2 proteins independent of the BH3 domain as shown by the BH3-lacking protein Bcl-x(AK).Enhancement of auranofin-induced apoptosis in MCF-7 human breast cells by selenocystine, a synergistic inhibitor of thioredoxin reductase.Simultaneous knock-down of Bcl-xL and Mcl-1 induces apoptosis through Bax activation in pancreatic cancer cellsVariola virus F1L is a Bcl-2-like protein that unlike its vaccinia virus counterpart inhibits apoptosis independent of Bim.Mitochondria and apoptosis: emerging concepts.ERK2 phosphorylation of serine 77 regulates Bmf pro-apoptotic activityBak Conformational Changes Induced by Ligand Binding: Insight into BH3 Domain Binding and Bak Homo-OligomerizationBH3-only proteins in apoptosis at a glanceAn interconnected hierarchical model of cell death regulation by the BCL-2 familyConstitutive BAK activation as a determinant of drug sensitivity in malignant lymphohematopoietic cells.γ-Secretase inhibition promotes cell death, Noxa upregulation, and sensitization to BH3 mimetic ABT-737 in human breast cancer cells.Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax.BCR-signaling-induced cell death demonstrates dependency on multiple BH3-only proteins in a murine model of B-cell lymphoma.Mitochondrial ATF2 translocation contributes to apoptosis induction and BRAF inhibitor resistance in melanoma through the interaction of Bim with VDAC1.Direct activation of full-length proapoptotic BAKInactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane.BAK/BAX activation and cytochrome c release assays using isolated mitochondria.Identification of an activation site in Bak and mitochondrial Bax triggered by antibodies.Multimodal interaction with BCL-2 family proteins underlies the proapoptotic activity of PUMA BH3Ouabain-induced apoptosis in cochlear hair cells and spiral ganglion neurons in vitro.(ADP-ribose) polymerase 1 and AMP-activated protein kinase mediate progressive dopaminergic neuronal degeneration in a mouse model of Parkinson's disease.Interrogating the relevance of mitochondrial apoptosis for vertebrate development and postnatal tissue homeostasisEvaluation of the BH3-only protein Puma as a direct Bak activatorBax/Bak activation in the absence of Bid, Bim, Puma, and p53.Death upon a kiss: mitochondrial outer membrane composition and organelle communication govern sensitivity to BAK/BAX-dependent apoptosis.Regulation of pancreatic β-cell survival by nitric oxide: clinical relevance.The fourth dimension in immunological space: how the struggle for nutrients selects high-affinity lymphocytes.Apoptosis regulation at the mitochondrial outer membrane.Many players in BCL-2 family affairs.Mitochondrial channels: ion fluxes and more.The Bcl-2 family: structures, interactions and targets for drug discovery.
P2860
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P248
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P2860
BH3 domains other than Bim and Bid can directly activate Bax/Bak
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
BH3 domains other than Bim and Bid can directly activate Bax/Bak
@ast
BH3 domains other than Bim and Bid can directly activate Bax/Bak
@en
BH3 domains other than Bim and Bid can directly activate Bax/Bak
@en-gb
BH3 domains other than Bim and Bid can directly activate Bax/Bak
@nl
type
label
BH3 domains other than Bim and Bid can directly activate Bax/Bak
@ast
BH3 domains other than Bim and Bid can directly activate Bax/Bak
@en
BH3 domains other than Bim and Bid can directly activate Bax/Bak
@en-gb
BH3 domains other than Bim and Bid can directly activate Bax/Bak
@nl
prefLabel
BH3 domains other than Bim and Bid can directly activate Bax/Bak
@ast
BH3 domains other than Bim and Bid can directly activate Bax/Bak
@en
BH3 domains other than Bim and Bid can directly activate Bax/Bak
@en-gb
BH3 domains other than Bim and Bid can directly activate Bax/Bak
@nl
P2093
P2860
P921
P3181
P356
P1476
BH3 domains other than Bim and Bid can directly activate Bax/Bak
@en
P2093
Blanca Schafer
Jacob Wolf
Tomomi Kuwana
P2860
P304
P3181
P356
10.1074/JBC.M110.167148
P407
P577
2011-01-07T00:00:00Z