Bordetella pertussis infection induces a mucosal IL-17 response and long-lived Th17 and Th1 immune memory cells in nonhuman primates.
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Mechanisms of Bacterial Colonization of the Respiratory TractRoads to the development of improved pertussis vaccines paved by immunologyNonhuman primate and human challenge models of pertussisProteomics-identified Bvg-activated autotransporters protect against bordetella pertussis in a mouse model.Review of the neutrophil response to Bordetella pertussis infection.Different effects of whole-cell and acellular vaccines on Bordetella transmission.Maternal and neonatal vaccination protects newborn baboons from pertussis infectionMolecular signatures of the evolving immune response in mice following a Bordetella pertussis infection.Bordetella pertussis pathogenesis: current and future challenges.Acellular pertussis vaccines protect against disease but fail to prevent infection and transmission in a nonhuman primate model.The hierarchical process of differentiation of long-lived antibody-secreting cells is dependent on integrated signals derived from antigen and IL-17A.The contribution of non-human primate models to the development of human vaccinesImmunological Signatures after Bordetella pertussis Infection Demonstrate Importance of Pulmonary Innate Immune CellsComparison of Three Whole-Cell Pertussis Vaccines in the Baboon Model of PertussisTranscriptome signature for dampened Th2 dominance in acellular pertussis vaccine-induced CD4(+) T cell responses through TLR4 ligation.Development of improved pertussis vaccine.Clinical consequences of targeting IL-17 and TH17 in autoimmune and allergic disordersBordetella pertussis outer membrane vesicle vaccine confers equal efficacy in mice with milder inflammatory responses compared to a whole-cell vaccine.Prior exposure to Bordetella species as an exclusion criterion in the baboon model of pertussis.Attenuated Bordetella pertussis vaccine protects against respiratory syncytial virus disease via an IL-17-dependent mechanism.Th17 memory cells: live long and proliferate.Dysregulation in lung immunity - the protective and pathologic Th17 response in infection.A tale of two cytokines: IL-17 and IL-22 in asthma and infection.Adult pertussis in the pre- and post-vaccine eras: lifelong vaccine-induced immunity?Pathogenesis and histopathology of pertussis: implications for immunization.Improved pertussis vaccines based on adjuvants that induce cell-mediated immunity.Bordetella pertussis fimbriae (Fim): relevance for vaccines.The baboon model of pertussis: effective use and lessons for pertussis vaccines.Genetically detoxified pertussis toxin (PT-9K/129G): implications for immunization and vaccines.Filamentous hemagglutinin of Bordetella pertussis: a key adhesin with immunomodulatory properties?Investigating pertussis toxin and its impact on vaccination.T-cell immune responses to Bordetella pertussis infection and vaccination.CD71+ erythroid suppressor cells impair adaptive immunity against Bordetella pertussis.Yin and yang of interleukin-17 in host immunity to infection.The Pertussis resurgence: putting together the pieces of the puzzle.What Is Wrong with Pertussis Vaccine Immunity? Inducing and Recalling Vaccine-Specific Immunity.MV140, a sublingual polyvalent bacterial preparation to treat recurrent urinary tract infections, licenses human dendritic cells for generating Th1, Th17, and IL-10 responses via Syk and MyD88.Vaccine-induced Th17 cells are established as resident memory cells in the lung and promote local IgA responses.Plasmacytoid dendritic cell-derived IFNα modulates Th17 differentiation during early Bordetella pertussis infection in mice.The relationship between mucosal immunity, nasopharyngeal carriage, asymptomatic transmission and the resurgence of Bordetella pertussis.
P2860
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P2860
Bordetella pertussis infection induces a mucosal IL-17 response and long-lived Th17 and Th1 immune memory cells in nonhuman primates.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh-hant
name
Bordetella pertussis infection ...... ry cells in nonhuman primates.
@en
Bordetella pertussis infection ...... ry cells in nonhuman primates.
@nl
type
label
Bordetella pertussis infection ...... ry cells in nonhuman primates.
@en
Bordetella pertussis infection ...... ry cells in nonhuman primates.
@nl
prefLabel
Bordetella pertussis infection ...... ry cells in nonhuman primates.
@en
Bordetella pertussis infection ...... ry cells in nonhuman primates.
@nl
P2860
P356
P1433
P1476
Bordetella pertussis infection ...... ry cells in nonhuman primates.
@en
P2093
J M Warfel
T J Merkel
P2860
P2888
P304
P356
10.1038/MI.2012.117
P577
2012-11-28T00:00:00Z