Discovery and optimization of selective inhibitors of protein arginine methyltransferase 5 by docking-based virtual screening.

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Epigenetic control via allosteric regulation of mammalian protein arginine methyltransferases.Computer-Aided Drug Design in Epigenetics.The Methylation Status of the Epigenome: Its Emerging Role in the Regulation of Tumor Angiogenesis and Tumor Growth, and Potential for Drug Targeting

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P2860

Discovery and optimization of selective inhibitors of protein arginine methyltransferase 5 by docking-based virtual screening.

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Bing Zhou

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Cheng Luo

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Chenhua Zhang

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Hong Ding

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Hualiang Jiang

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Kaixian Chen

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Ruifeng Mao

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Xiaomin Luo

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Yan Ye

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P2860

Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase

Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes

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PRMT9 is a type II methyltransferase that methylates the splicing factor SAP145

Discovery of inhibitors of Schistosoma mansoni HDAC8 by combining homology modeling, virtual screening, and in vitro validation.

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scholarly article

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Jing Xing

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Discovery and optimization of selective inhibitors of protein arginine methyltransferase 5 by docking-based virtual screening.

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P2860

P2860

Discovery and optimization of selective inhibitors of protein arginine methyltransferase 5 by docking-based virtual screening.

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