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Purified salograviolide A isolated from centaurea ainetensis causes growth inhibition and apoptosis in neoplastic epidermal cells.What made sesquiterpene lactones reach cancer clinical trials?Copper chelation selectively kills colon cancer cells through redox cycling and generation of reactive oxygen speciesThymoquinone: a promising anti-cancer drug from natural sources.Thymoquinone triggers inactivation of the stress response pathway sensor CHEK1 and contributes to apoptosis in colorectal cancer cells.Modulating cell cycle: current applications and prospects for future drug development.Radiosensitization by 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide under oxia and hypoxia in human colon cancer cells.Overview of major classes of plant-derived anticancer drugsThe radiosensitizer 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide induces DNA damage in EMT-6 mammary carcinoma cells.Thymoquinone reduces mouse colon tumor cell invasion and inhibits tumor growth in murine colon cancer models.The quinoxaline di-N-oxide DCQ blocks breast cancer metastasis in vitro and in vivo by targeting the hypoxia inducible factor-1 pathway.Cell cycle modulatory and apoptotic effects of plant-derived anticancer drugs in clinical use or development.Targeting hypoxia for sensitization of tumors to radio- and chemotherapy.The photoprotective effects of 2-benzoyl-3-phenylquinoxaline 1,4-dioxide against UVB-induced damage in HaCaT cells.Overview of the Formulations and Analogs in the Taxanes' Story.Thymoquinone-induced conformational changes of PAK1 interrupt prosurvival MEK-ERK signaling in colorectal cancer.Gallotannin is a DNA damaging compound that induces senescence independently of p53 and p21 in human colon cancer cells.Emerging Cytotoxic Alkaloids in the Battle against Cancer: Overview of Molecular Mechanisms.Synthesis, properties, and antitumor effects of a new mixed phosphine gold(I) compound in human colon cancer cells.DAPK plays an important role in panobinostat-induced autophagy and commits cells to apoptosis under autophagy deficient conditions.Gallotannin inhibits NFĸB signaling and growth of human colon cancer xenografts.Cell death by the quinoxaline dioxide DCQ in human colon cancer cells is enhanced under hypoxia and is independent of p53 and p21Cutting edge: Chk1 directs senescence and mitotic catastrophe in recovery from G₂ checkpoint arrest.Alpha terpineol: a potential anticancer agent which acts through suppressing NF-kappaB signalling.Reactive oxygen species mediate thymoquinone-induced apoptosis and activate ERK and JNK signaling.Radiosensitization of EMT6 mammary carcinoma cells by 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide.Onopordum cynarocephalum induces apoptosis and protects against 1,2 dimethylhydrazine-induced colon cancer.Lack of p53 augments thymoquinone-induced apoptosis and caspase activation in human osteosarcoma cells.Regulation of ultraviolet B radiation-mediated activation of AP1 signaling by retinoids in primary keratinocytes.5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45- and p53-dependent mechanisms.Thymoquinone extracted from black seed triggers apoptotic cell death in human colorectal cancer cells via a p53-dependent mechanism.Inhibition of proliferation and induction of apoptosis by 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide in adult T-cell leukemia cells.Protective effect of vitamin E on ultraviolet B light-induced damage in keratinocytes.Quinoxaline 1,4-dioxides are novel angiogenesis inhibitors that potentiate antitumor effects of ionizing radiation.Synthesis of Novel Hybrids of Thymoquinone and Artemisinin with High Activity and Selectivity Against Colon Cancer.Retraction notice to Inhibition of proliferation and induction of apoptosis by 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide in adult T-cell leukemia cells.Mechanism of action of the atypical retinoid ST1926 in colorectal cancer: DNA damage and DNA polymerase α.Hsp90 inhibition by AUY922 as an effective treatment strategy against myxoid liposarcoma.The Cytotoxic and Apoptotic Effects of the Brown Algae Colpomenia sinuosa are Mediated by the Generation of Reactive Oxygen Species
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description
researcher
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wetenschapper
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հետազոտող
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Hala Gali-Muhtasib
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Hala Gali-Muhtasib
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Hala Gali-Muhtasib
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Hala Gali-Muhtasib
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Hala Gali-Muhtasib
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Hala Gali-Muhtasib
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Hala Gali-Muhtasib
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Hala Gali-Muhtasib
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Hala Gali-Muhtasib
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Hala Gali-Muhtasib
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Hala Gali-Muhtasib
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Hala Gali-Muhtasib
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Hala Gali-Muhtasib
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Hala Gali-Muhtasib
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P106
P31
P496
0000-0001-6840-3015