Reactive oxygen species mediate thymoquinone-induced apoptosis and activate ERK and JNK signaling.
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Recent advances on the anti-cancer properties of Nigella sativa, a widely used food additiveAnticancer activity of Nigella sativa (black seed) - a reviewThymoquinone inhibits tumor growth and induces apoptosis in a breast cancer xenograft mouse model: the role of p38 MAPK and ROSThymoquinone inhibits autophagy and induces cathepsin-mediated, caspase-independent cell death in glioblastoma cellsThymoquinone inhibits murine leukemia WEHI-3 cells in vivo and in vitroPotentiation of epithelial innate host responses by intercellular communication.Essential oils and their constituents as anticancer agents: a mechanistic view.Effects of thymoquinone in the expression of mucin 4 in pancreatic cancer cells: implications for the development of novel cancer therapiesERKs and mitochondria-related pathways are essential for glycyrrhizic acid-mediated neuroprotection against glutamate-induced toxicity in differentiated PC12 cells.Differential effects of arsenic trioxide on chemosensitization in human hepatic tumor and stellate cell linesAntineoplastic and apoptotic potential of traditional medicines thymoquinone and diosgenin in squamous cell carcinoma.Cardio-protective and anti-cancer therapeutic potential of Nigella sativa.Anticancer activity of essential oils and their chemical components - a review.Compound K, a metabolite of ginseng saponin, induces mitochondria-dependent and caspase-dependent apoptosis via the generation of reactive oxygen species in human colon cancer cellsDown-regulation of nicotinamide N-methyltransferase induces apoptosis in human breast cancer cells via the mitochondria-mediated pathwayLicochalcone A-induced human gastric cancer BGC-823 cells apoptosis by regulating ROS-mediated MAPKs and PI3K/AKT signaling pathwaysEffect of FK506 in reducing scar formation by inducing fibroblast apoptosis after sciatic nerve injury in rats.Effect of Thymoquinone on P53 Gene Expression and Consequence Apoptosis in Breast Cancer Cell LineGalangin inhibits cell invasion by suppressing the epithelial-mesenchymal transition and inducing apoptosis in renal cell carcinoma.Redox cycling of endogenous copper by thymoquinone leads to ROS-mediated DNA breakage and consequent cell death: putative anticancer mechanism of antioxidants.Compound K induces apoptosis of bladder cancer T24 cells via reactive oxygen species-mediated p38 MAPK pathway.Thymoquinone chemosensitizes colon cancer cells through inhibition of NF-κB.Liquiritigenin induces tumor cell death through mitogen-activated protein kinase- (MPAKs-) mediated pathway in hepatocellular carcinoma cellsThymoquinone potentiates chemoprotective effect of Vitamin D3 against colon cancer: a pre-clinical finding.Genetic determinants of oxidative stress-mediated sensitization of drug-resistant cancer cells.A CD13 inhibitor, ubenimex, synergistically enhances the effects of anticancer drugs in hepatocellular carcinoma.Inhibition of NF-κB and metastasis in irinotecan (CPT-11)-resistant LoVo colon cancer cells by thymoquinone via JNK and p38.Inhibition of heme oxygenase-1 enhances the chemosensitivity of laryngeal squamous cell cancer Hep-2 cells to cisplatin.Cinobufagin exerts anti-proliferative and pro-apoptotic effects through the modulation ROS-mediated MAPKs signaling pathway.Curcumin induced human gastric cancer BGC-823 cells apoptosis by ROS-mediated ASK1-MKK4-JNK stress signaling pathway.Thymoquinone-induced conformational changes of PAK1 interrupt prosurvival MEK-ERK signaling in colorectal cancer.Dual cell protective mechanisms activated by differing levels of oxidative stress in HT22 murine hippocampal cells.6-Shogaol exerts anti-proliferative and pro-apoptotic effects through the modulation of STAT3 and MAPKs signaling pathways.Thymoquinone, a bioactive component of black caraway seeds, causes G1 phase cell cycle arrest and apoptosis in triple-negative breast cancer cells with mutant p53.Apoptosis of bladder transitional cell carcinoma T24 cells induced by adenovirus-mediated inducible nitric oxide synthase gene transfection.18beta-glycyrrhetinic acid induces apoptosis in pituitary adenoma cells via ROS/MAPKs-mediated pathway.Neferine, an alkaloid from lotus seed embryo, inhibits human lung cancer cell growth by MAPK activation and cell cycle arrest.Pronounced transcriptional regulation of apoptotic and TNF-NF-kappa-B signaling genes during the course of thymoquinone mediated apoptosis in HeLa cells.Anti-cancer properties and mechanisms of action of thymoquinone, the major active ingredient of Nigella sativa.Involvement of MAPK activation and ROS generation in human leukemia U937 cells undergoing apoptosis in response to sonodynamic therapy.
P2860
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P2860
Reactive oxygen species mediate thymoquinone-induced apoptosis and activate ERK and JNK signaling.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Reactive oxygen species mediat ...... ctivate ERK and JNK signaling.
@en
Reactive oxygen species mediat ...... ctivate ERK and JNK signaling.
@nl
type
label
Reactive oxygen species mediat ...... ctivate ERK and JNK signaling.
@en
Reactive oxygen species mediat ...... ctivate ERK and JNK signaling.
@nl
prefLabel
Reactive oxygen species mediat ...... ctivate ERK and JNK signaling.
@en
Reactive oxygen species mediat ...... ctivate ERK and JNK signaling.
@nl
P2093
P2860
P50
P1433
P1476
Reactive oxygen species mediat ...... ctivate ERK and JNK signaling.
@en
P2093
Hala Gali-Muhtasib
Heikki Vuorela
Hiba Moukadem
Manal Chatila
Muktheshwar Gandesiri
Nahed El-Najjar
Regine Schneider-Stock
P2860
P2888
P304
P356
10.1007/S10495-009-0421-Z
P577
2010-02-01T00:00:00Z