about
Seven new mutations in hMSH2, an HNPCC gene, identified by denaturing gradient-gel electrophoresisFamilial endometrial cancer in female carriers of MSH6 germline mutationsEXO1 variants occur commonly in normal population: evidence against a role in hereditary nonpolyposis colorectal cancerRisks of Lynch syndrome cancers for MSH6 mutation carriers.Cost-utility analysis of genetic screening in families of patients with germline MUTYH mutationsColorectal carcinomas in MUTYH-associated polyposis display histopathological similarities to microsatellite unstable carcinomasDecision analysis in the management of duodenal adenomatosis in familial adenomatous polyposis.Treatment of mesenteric desmoid tumours with the anti-oestrogenic agent toremifene: case histories and an overview of the literature.Familial adenomatous polyposis: from bedside to bench and vice versa. A tribute to the somatic cell geneticist P. Meera Khan.The CHEK2 1100delC mutation identifies families with a hereditary breast and colorectal cancer phenotype.Targeted prostate cancer screening in BRCA1 and BRCA2 mutation carriers: results from the initial screening round of the IMPACT studyColorectal cancer and family history.Survival of MUTYH-associated polyposis patients with colorectal cancer and matched control colorectal cancer patientsAttitudes toward genetic testing in childhood and reproductive decision-making for familial adenomatous polyposis.Clinical heterogeneity of familial colorectal cancer and its influence on screening protocols.Evaluation of management of desmoid tumours associated with familial adenomatous polyposis in Dutch patients.Detection of pancreatic cancer using serum protein profiling.Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis.Effectiveness and causes for failure of surveillance of CDKN2A-mutated melanoma families.Germline variants in POLE are associated with early onset mismatch repair deficient colorectal cancerSerum peptide signatures for pancreatic cancer based on mass spectrometry: a comparison to CA19-9 levels and routine imaging techniques.Risk of colorectal and endometrial cancer for carriers of mutations of the hMLH1 and hMSH2 gene: correction for ascertainmentProspective risk of cancer and the influence of tobacco use in carriers of the p16-Leiden germline variant.Bannayan-Riley-Ruvalcaba syndrome: further delineation of the phenotype and management of PTEN mutation-positive cases.Quality of colonoscopy in Lynch syndromeDuodenal adenomatosis in familial adenomatous polyposis.High-resolution melting (HRM) re-analysis of a polyposis patients cohort reveals previously undetected heterozygous and mosaic APC gene mutations.Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trialSurveillance for familial pancreatic cancer.Pancreatic cancer-associated gene polymorphisms in a nation-wide cohort of p16-Leiden germline mutation carriers; a case-control study.Conventional and tissue microarray immunohistochemical expression analysis of mismatch repair in hereditary colorectal tumors.Majority of hMLH1 mutations responsible for hereditary nonpolyposis colorectal cancer cluster at the exonic region 15-16Identification of HNPCC by molecular analysis of colorectal and endometrial tumors.Mutations associated with HNPCC predisposition -- Update of ICG-HNPCC/INSiGHT mutation database.Increased risk of colorectal neoplasia in asymptomatic liver-transplant recipients.Is surveillance of the small bowel indicated for Lynch syndrome families?Application of a Serum Protein Signature for Pancreatic Cancer to Separate Cases from Controls in a Pancreatic Surveillance Cohort.Whole Gene Capture Analysis of 15 CRC Susceptibility Genes in Suspected Lynch Syndrome Patients.Loss-of-Function Mutations in the Cell-Cycle Control Gene CDKN2A Impact on Glucose Homeostasis in Humans.Diagnostic approach and management of Lynch syndrome (hereditary nonpolyposis colorectal carcinoma): a guide for clinicians.
P50
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P50
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P108
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0000-0003-2682-2603