Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems.
about
Engineering Plant Immunity: Using CRISPR/Cas9 to Generate Virus ResistanceDNA editing in DNA/RNA hybrids by adenosine deaminases that act on RNA.Genome engineering of stem cell organoids for disease modeling.pKAMA-ITACHI Vectors for Highly Efficient CRISPR/Cas9-Mediated Gene Knockout in Arabidopsis thaliana.Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery.Mutations in human AID differentially affect its ability to deaminate cytidine and 5-methylcytidine in ssDNA substrates in vitroAptazyme-embedded guide RNAs enable ligand-responsive genome editing and transcriptional activation.Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells.Rapid generation of drug-resistance alleles at endogenous loci using CRISPR-Cas9 indel mutagenesis.Functional interrogation of non-coding DNA through CRISPR genome editing.CRISPR Editing in Biological and Biomedical Investigation.Progress and prospects in plant genome editing.Developmental history and application of CRISPR in human disease.CRISPR Editing Technology in Biological and Biomedical Investigation.Plant genome editing with TALEN and CRISPR.Editing the genome of hiPSC with CRISPR/Cas9: disease models.CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes.Cornerstones of CRISPR-Cas in drug discovery and therapy.Genome editing of crops: A renewed opportunity for food security.Functional variomics and network perturbation: connecting genotype to phenotype in cancer.New variants of CRISPR RNA-guided genome editing enzymes.CRISPR/Cas system for yeast genome engineering: advances and applications.Treatment of Dyslipidemia Using CRISPR/Cas9 Genome Editing.Cellular Reprogramming, Genome Editing, and Alternative CRISPR Cas9 Technologies for Precise Gene Therapy of Duchenne Muscular Dystrophy.Programmable base editing of zebrafish genome using a modified CRISPR-Cas9 system.Editing base in mouse model.Optimised metrics for CRISPR-KO screens with second-generation gRNA libraries.Development of a comprehensive set of tools for genome engineering in a cold- and thermo-tolerant Kluyveromyces marxianus yeast strainImproved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity.Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusionsEffective gene editing by high-fidelity base editor 2 in mouse zygotes.Highly efficient base editing in human tripronuclear zygotes.Development of a genetic sensor that eliminates p53 deficient cells.In Vivo Base Editing of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) as a Therapeutic Alternative to Genome Editing.Immunity to CRISPR Cas9 and Cas12a therapeutics.Genome Editing: The Recent History and Perspective in Cardiovascular Diseases.Editing the Genome Without Double-Stranded DNA Breaks.Genome Modification Technologies and Their Applications in Avian Species.CRISPR-Mediated Base Editing Enables Efficient Disruption of Eukaryotic Genes through Induction of STOP Codons.Targeted Base Editing via RNA-Guided Cytidine Deaminases in Xenopus laevis Embryos.
P2860
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P2860
Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
Targeted nucleotide editing us ...... brate adaptive immune systems.
@en
Targeted nucleotide editing us ...... brate adaptive immune systems.
@nl
type
label
Targeted nucleotide editing us ...... brate adaptive immune systems.
@en
Targeted nucleotide editing us ...... brate adaptive immune systems.
@nl
prefLabel
Targeted nucleotide editing us ...... brate adaptive immune systems.
@en
Targeted nucleotide editing us ...... brate adaptive immune systems.
@nl
P2093
P2860
P356
P1433
P1476
Targeted nucleotide editing us ...... brate adaptive immune systems.
@en
P2093
Akihiko Kondo
Aya Miyabe
Keiji Nishida
Kiyotaka Y Hara
Masao Mochizuki
Mayura Tabata
Michihiro Araki
Mika Kakimoto
Nozomu Yachie
Takayuki Arazoe
P2860
P356
10.1126/SCIENCE.AAF8729
P407
P50
P577
2016-08-04T00:00:00Z