Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems. - Wikidata - wikimedia - TriplyDB

Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems.

Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems.

http://www.wikidata.org/entity/Q51215555

about

Engineering Plant Immunity: Using CRISPR/Cas9 to Generate Virus Resistance DNA editing in DNA/RNA hybrids by adenosine deaminases that act on RNA.Genome engineering of stem cell organoids for disease modeling.pKAMA-ITACHI Vectors for Highly Efficient CRISPR/Cas9-Mediated Gene Knockout in Arabidopsis thaliana.Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery.Mutations in human AID differentially affect its ability to deaminate cytidine and 5-methylcytidine in ssDNA substrates in vitro Aptazyme-embedded guide RNAs enable ligand-responsive genome editing and transcriptional activation.Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells.Rapid generation of drug-resistance alleles at endogenous loci using CRISPR-Cas9 indel mutagenesis.Functional interrogation of non-coding DNA through CRISPR genome editing.CRISPR Editing in Biological and Biomedical Investigation.Progress and prospects in plant genome editing.Developmental history and application of CRISPR in human disease.CRISPR Editing Technology in Biological and Biomedical Investigation.Plant genome editing with TALEN and CRISPR.Editing the genome of hiPSC with CRISPR/Cas9: disease models.CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes.Cornerstones of CRISPR-Cas in drug discovery and therapy.Genome editing of crops: A renewed opportunity for food security.Functional variomics and network perturbation: connecting genotype to phenotype in cancer.New variants of CRISPR RNA-guided genome editing enzymes.CRISPR/Cas system for yeast genome engineering: advances and applications.Treatment of Dyslipidemia Using CRISPR/Cas9 Genome Editing.Cellular Reprogramming, Genome Editing, and Alternative CRISPR Cas9 Technologies for Precise Gene Therapy of Duchenne Muscular Dystrophy.Programmable base editing of zebrafish genome using a modified CRISPR-Cas9 system.Editing base in mouse model.Optimised metrics for CRISPR-KO screens with second-generation gRNA libraries.Development of a comprehensive set of tools for genome engineering in a cold- and thermo-tolerant Kluyveromyces marxianus yeast strain Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity.Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions Effective gene editing by high-fidelity base editor 2 in mouse zygotes.Highly efficient base editing in human tripronuclear zygotes.Development of a genetic sensor that eliminates p53 deficient cells.In Vivo Base Editing of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) as a Therapeutic Alternative to Genome Editing.Immunity to CRISPR Cas9 and Cas12a therapeutics.Genome Editing: The Recent History and Perspective in Cardiovascular Diseases.Editing the Genome Without Double-Stranded DNA Breaks.Genome Modification Technologies and Their Applications in Avian Species.CRISPR-Mediated Base Editing Enables Efficient Disruption of Eukaryotic Genes through Induction of STOP Codons.Targeted Base Editing via RNA-Guided Cytidine Deaminases in Xenopus laevis Embryos.

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P2860

Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems.

http://www.wikidata.org/entity/Q51215555

description

2016 nî lūn-bûn

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2016年の論文

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年學術文章

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2016年學術文章

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2016年學術文章

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name

Targeted nucleotide editing us ...... brate adaptive immune systems.

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Targeted nucleotide editing us ...... brate adaptive immune systems.

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type

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Targeted nucleotide editing us ...... brate adaptive immune systems.

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Targeted nucleotide editing us ...... brate adaptive immune systems.

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prefLabel

Targeted nucleotide editing us ...... brate adaptive immune systems.

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Targeted nucleotide editing us ...... brate adaptive immune systems.

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SCIENCE.AAF8729

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Targeted nucleotide editing us ...... brate adaptive immune systems.

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Akihiko Kondo

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Aya Miyabe

http://www.w3.org/2001/XMLSchema#string

Keiji Nishida

http://www.w3.org/2001/XMLSchema#string

Kiyotaka Y Hara

http://www.w3.org/2001/XMLSchema#string

Masao Mochizuki

http://www.w3.org/2001/XMLSchema#string

Mayura Tabata

http://www.w3.org/2001/XMLSchema#string

Michihiro Araki

http://www.w3.org/2001/XMLSchema#string

Mika Kakimoto

http://www.w3.org/2001/XMLSchema#string

Nozomu Yachie

http://www.w3.org/2001/XMLSchema#string

Takayuki Arazoe

http://www.w3.org/2001/XMLSchema#string

P2860

CCTop: An Intuitive, Flexible and Reliable CRISPR/Cas9 Target Prediction Tool

Cas9 as a versatile tool for engineering biology

RNA-guided editing of bacterial genomes using CRISPR-Cas systems

Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

Development and applications of CRISPR-Cas9 for genome engineering.

Genome-wide mutation avalanches induced in diploid yeast cells by a base analog or an APOBEC deaminase

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

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10.1126/SCIENCE.AAF8729

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353

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2016-08-04T00:00:00Z

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27492474

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