Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors.

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The small molecule MERTK inhibitor UNC2025 decreases platelet activation and prevents thrombosis.

P2860

Q45873319-4734900B-CE4C-4F16-827F-705D9FD45BE7

P2860

Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors.

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http://www.wikidata.org/entity/Q51229257

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2016 nî lūn-bûn

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2016年の論文

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2016年学术文章

@wuu

2016年学术文章

@zh-cn

2016年学术文章

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2016年学术文章

@zh-my

2016年学术文章

@zh-sg

2016年學術文章

@yue

2016年學術文章

@zh

2016年學術文章

@zh-hant

name

Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors.

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Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors.

@nl

type

Item

label

Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors.

@en

Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors.

@nl

prefLabel

Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors.

@en

Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors.

@nl

P1476

Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors.

@en

P2093

Andrew L McIver

http://www.w3.org/2001/XMLSchema#string

Deborah DeRyckere

http://www.w3.org/2001/XMLSchema#string

Dmitri Kireev

http://www.w3.org/2001/XMLSchema#string

Douglas K Graham

http://www.w3.org/2001/XMLSchema#string

Edgar Wood

http://www.w3.org/2001/XMLSchema#string

H Shelton Earp

http://www.w3.org/2001/XMLSchema#string

Jacqueline Norris-Drouin

http://www.w3.org/2001/XMLSchema#string

James Nichols

http://www.w3.org/2001/XMLSchema#string

Michael A Stashko

http://www.w3.org/2001/XMLSchema#string

Michael J Miley

http://www.w3.org/2001/XMLSchema#string

P2860

Cloning and mRNA expression analysis of a novel human protooncogene, c-mer

Discovery of Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia

Pseudo-Cyclization through Intramolecular Hydrogen Bond Enables Discovery of Pyridine Substituted Pyrimidines as New Mer Kinase Inhibitors

Discovery of Mer Specific Tyrosine Kinase Inhibitors for the Treatment and Prevention of Thrombosis

Synthesis of P1'-functionalized macrocyclic transition-state mimicking HIV-1 protease inhibitors encompassing a tertiary alcohol

UNC1062, a new and potent Mer inhibitor.

Two simple and generic antibody-independent kinase assays: comparison of a bioluminescent and a microfluidic assay format.

A chemogenomic analysis of the human proteome: application to enzyme families.

UNC2025, a potent and orally bioavailable MER/FLT3 dual inhibitor.

A phase 2 trial of the FLT3 inhibitor lestaurtinib (CEP701) as first-line treatment for older patients with acute myeloid leukemia not considered fit for intensive chemotherapy.

P304

207-213

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P31

scholarly article

P356

10.1002/CMDC.201600589

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Mischa Machius

P577

2016-12-28T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

28032464

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P932

5336325

http://www.w3.org/2001/XMLSchema#string

Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors.

about

P2860

P2860

Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors.

description

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type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932