Macrocyclic MEK1/2 inhibitor with efficacy in a mouse model of cardiomyopathy caused by lamin A/C gene mutation.
about
Cell signaling abnormalities in cardiomyopathy caused by lamin A/C gene mutations.Elevated dual specificity protein phosphatase 4 in cardiomyopathy caused by lamin A/C gene mutation is primarily ERK1/2-dependent and its depletion improves cardiac function and survival.Cofilin-1 phosphorylation catalyzed by ERK1/2 alters cardiac actin dynamics in dilated cardiomyopathy caused by lamin A/C gene mutation.Mechanotransduction, nuclear architecture and epigenetics in Emery Dreifuss Muscular Dystrophy: tous pour un, un pour tous.Role of Lamin A/C Gene Mutations in the Signaling Defects Leading to CardiomyopathiesThe Pathogenesis and Therapies of Striated Muscle Laminopathies
P2860
Macrocyclic MEK1/2 inhibitor with efficacy in a mouse model of cardiomyopathy caused by lamin A/C gene mutation.
description
2016 nî lūn-bûn
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2016年の論文
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2016年学术文章
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2016年学术文章
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2016年学术文章
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2016年学术文章
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2016年学术文章
@zh-my
2016年学术文章
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2016年學術文章
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2016年學術文章
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name
Macrocyclic MEK1/2 inhibitor w ...... ed by lamin A/C gene mutation.
@en
Macrocyclic MEK1/2 inhibitor w ...... ed by lamin A/C gene mutation.
@nl
type
label
Macrocyclic MEK1/2 inhibitor w ...... ed by lamin A/C gene mutation.
@en
Macrocyclic MEK1/2 inhibitor w ...... ed by lamin A/C gene mutation.
@nl
prefLabel
Macrocyclic MEK1/2 inhibitor w ...... ed by lamin A/C gene mutation.
@en
Macrocyclic MEK1/2 inhibitor w ...... ed by lamin A/C gene mutation.
@nl
P2093
P2860
P1476
Macrocyclic MEK1/2 inhibitor w ...... ed by lamin A/C gene mutation.
@en
P2093
Ajay Bhargava
Barry P Hart
E Sathyajith Kumarasinghe
Fusako Sera
Howard J Worman
Ji-Yeon Shin
Michael W Lawlor
Shunichi Homma
Uday R Khire
P2860
P304
P356
10.1016/J.BMC.2016.12.014
P407
P577
2016-12-09T00:00:00Z