Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice.
about
Role of bile acids in the regulation of the metabolic pathwaysBile Acid Metabolism and Signaling in Cholestasis, Inflammation, and CancerRecent advances in gut nutrient chemosensingBile acid metabolism and signalingBile acids, obesity, and the metabolic syndromeA Novel TGR5 Activator WB403 Promotes GLP-1 Secretion and Preserves Pancreatic β-Cells in Type 2 Diabetic MiceRole of bile acids in carcinogenesis of pancreatic cancer: An old topic with new perspective.Bile acid signaling in metabolic disease and drug therapyIdentification of miR-26a as a target gene of bile acid receptor GPBAR-1/TGR5Bile acid sequestrants for lipid and glucose control.Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitisGenetic variation in GPBAR1 predisposes to quantitative changes in colonic transit and bile acid excretion.Plasma bile acids are not associated with energy metabolism in humans.Nutritional regulation of bile acid metabolism is associated with improved pathological characteristics of the metabolic syndrome.Bile acid signaling and liver regeneration.The G protein-coupled bile acid receptor, TGR5, stimulates gallbladder fillingThe bile acid membrane receptor TGR5: a valuable metabolic target.TGR5: a novel target for weight maintenance and glucose metabolism.GPBAR1/TGR5 mediates bile acid-induced cytokine expression in murine Kupffer cells.Emerging science of the human microbiome.The G-protein-coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor κ light-chain enhancer of activated B cells (NF-κB) in miceOstα-/- mice are not protected from western diet-induced weight gainMetabolic effects of cholecystectomy: gallbladder ablation increases basal metabolic rate through G-protein coupled bile acid receptor Gpbar1-dependent mechanisms in mice.Bile acid metabolism and the pathogenesis of type 2 diabetes.TGR5 potentiates GLP-1 secretion in response to anionic exchange resins.Bile acid receptors as targets for the treatment of dyslipidemia and cardiovascular disease.Bile Acid Receptors and Liver Cancer.The TGR5 receptor mediates bile acid-induced itch and analgesiaTGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's diseaseThe bile acid membrane receptor TGR5 as an emerging target in metabolism and inflammation.Pleiotropic roles of bile acids in metabolism.Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling.The bile acid receptor TGR5 does not interact with β-arrestins or traffic to endosomes but transmits sustained signals from plasma membrane rafts.Deficiency of G-protein-coupled bile acid receptor Gpbar1 (TGR5) enhances chemically induced liver carcinogenesisThe Gut Microbiota as a Therapeutic Target in IBD and Metabolic Disease: A Role for the Bile Acid Receptors FXR and TGR5.TGR5 signaling reduces neuroinflammation during hepatic encephalopathy.Endocrine and paracrine role of bile acidsBile acids as regulatory molecules.Cholesteryl ester transfer protein protects against insulin resistance in obese female mice.Intercellular Lipid Mediators and GPCR Drug Discovery
P2860
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P2860
Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice.
description
2006 nî lūn-bûn
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2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
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2006年学术文章
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2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice.
@en
Targeted disruption of G protein-coupled bile acid receptor 1
@nl
type
label
Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice.
@en
Targeted disruption of G protein-coupled bile acid receptor 1
@nl
prefLabel
Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice.
@en
Targeted disruption of G protein-coupled bile acid receptor 1
@nl
P2093
P356
P1476
Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice
@en
P2093
Akio Kanatani
Jun Suzuki
Kenichi Tanaka
Naomoto Harada
Takaharu Maruyama
Takao Nakamura
Yasuhisa Miyamoto
Yoshitaka Tamai
P304
P356
10.1677/JOE.1.06546
P407
P577
2006-10-01T00:00:00Z