A mutation in Ihh that causes digit abnormalities alters its signalling capacity and range.
about
Indian hedgehog mutations causing brachydactyly type A1 impair Hedgehog signal transduction at multiple levelsThe structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signalingThe Hedgehog signalling pathway in bone formationReceptor tyrosine kinase-like orphan receptor 2 (ROR2) and Indian hedgehog regulate digit outgrowth mediated by the phalanx-forming regionMolecular development of fibular reduction in birds and its evolution from dinosaursLoss of function mutation in the palmitoyl-transferase HHAT leads to syndromic 46,XY disorder of sex development by impeding Hedgehog protein palmitoylation and signalingChronic obstructive pulmonary disease: towards pharmacogenetics.Mouse limb skeletal growth and synovial joint development are coordinately enhanced by Kartogenin.Identification of duplication downstream of BMP2 in a Chinese family with brachydactyly type A2 (BDA2).Signaling domain of Sonic Hedgehog as cannibalistic calcium-regulated zinc-peptidaseUse of a Conditional Ubr5 Mutant Allele to Investigate the Role of an N-End Rule Ubiquitin-Protein Ligase in Hedgehog Signalling and Embryonic Limb Development.Closely related bird species demonstrate flexibility between beak morphology and underlying developmental programs.Two novel disease-causing variants in BMPR1B are associated with brachydactyly type A1.Deletion of Indian hedgehog gene causes dominant semi-lethal Creeper trait in chickenPseudo-active sites of protease domains: HGF/Met and Sonic hedgehog signaling in cancer.Interactions between Hedgehog proteins and their binding partners come into view.Mechanisms of digit formation: Human malformation syndromes tell the story.Rising Strengths Hong Kong SAR in Bioinformatics.Missense mutations in IHH impair Indian Hedgehog signaling in C3H10T1/2 cells: Implications for brachydactyly type A1, and new targets for Hedgehog signaling.A cis-regulatory site downregulates PTHLH in translocation t(8;12)(q13;p11.2) and leads to Brachydactyly Type E.Glypican-6 promotes the growth of developing long bones by stimulating Hedgehog signaling.Identification of p.Glu131Lys Mutation in the IHH Gene in a Korean Patient With Brachydactyly Type A1.Mechanobiological modeling of endochondral ossification: an experimental and computational analysis.IHH gene polymorphism among three horse breeds and its application for association test in horses with osteochondrosis.Sufu and Kif7 in limb patterning and development.Inactivation of patched1 in murine chondrocytes causes spinal fusion without inflammation.Cooperation of BMP and IHH signaling in interdigital cell fate determination.
P2860
Q24301248-1B552A2F-B9D5-4EE3-86CC-DDC55B0F593EQ24308827-9A6C079C-F280-45D4-9F5B-504AA6693093Q28081609-7ED690CC-B202-46B6-B50D-7B66FE38A030Q28592556-A6CB4B9D-F0A1-4FED-B053-E80AAF67BBD1Q28597226-32D969AE-AF47-4FA7-9C55-F95E3D930147Q33553088-E1AEC712-4DD7-4358-A4DD-4E8908820721Q33600138-CE71F932-DB1B-4B10-B168-86E9383FF434Q34617259-8841868B-EB6D-4F81-BA0B-FD7D50796F96Q35142101-65556385-6A5B-4112-AC6B-03684460B23BQ35208287-984C51DB-4AAD-40EA-B2EB-8A71D0007D2BQ36051665-1DFC2B5D-468E-4888-9EFB-1A934368AAF1Q36342972-0C3C9577-52E8-44E2-B556-142D32C0E6E6Q36695753-B9E1D954-38D2-4275-9245-9A5056708D9EQ37112760-4FF4E11A-FAE0-427A-9AAD-46FA9C24E627Q37763945-CB001974-714E-4E7A-9BD5-52D58D8AB4BFQ37789106-5DA114F0-AB1B-4112-AD49-B4EBB2B03D4CQ37845326-FE058421-EC12-4183-92AB-3FC2106294B8Q38767580-B198DE9F-4EC7-4C73-B95A-77A981E18BD4Q39760924-49F71AF3-D9B6-4C94-9659-A02533F2700EQ42005057-98983DBE-372A-465F-B619-3EBE81AB4679Q42799207-4B161B43-13F5-43A6-9C9B-3BE43D23DEA2Q43225092-908D811E-81A6-49F0-8FBC-3CE926984A4BQ47565564-13F99103-F469-4FF1-B69B-02863258A01CQ47985113-C2FDB4DE-875A-4E35-BB36-048FF2EFFD8AQ50607969-C7711E10-3D7B-4BBB-A2B7-006324821027Q54570497-4F36AEE4-2990-43A2-AEF3-0596DE2A3AAFQ55021452-CDCAA52E-30D6-4512-A416-D8C9FF9F4F15
P2860
A mutation in Ihh that causes digit abnormalities alters its signalling capacity and range.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
A mutation in Ihh that causes ...... signalling capacity and range.
@en
A mutation in Ihh that causes ...... signalling capacity and range.
@nl
type
label
A mutation in Ihh that causes ...... signalling capacity and range.
@en
A mutation in Ihh that causes ...... signalling capacity and range.
@nl
prefLabel
A mutation in Ihh that causes ...... signalling capacity and range.
@en
A mutation in Ihh that causes ...... signalling capacity and range.
@nl
P2093
P50
P356
P1433
P1476
A mutation in Ihh that causes ...... signalling capacity and range.
@en
P2093
Danny Chan
Florian Witte
Jianxin Hu
Kathryn S E Cheah
Kit Fong Law
Martin Cheung
Stefan Mundlos
P2888
P304
P356
10.1038/NATURE07862
P407
P577
2009-03-01T00:00:00Z
P5875
P6179
1007615628